3,3-dichloro-2,2-dimethylpropionyl chloride | 81777-82-4

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 酰卤
• 英文名称: 3,3-dichloro-2,2-dimethylpropionyl chloride
• 英文别名: 3,3-dichloropivaloyl chloride；dichloropivaloyl chloride；3,3-Dichloro-2,2-dimethylpropanoyl chloride
• CAS: 81777-82-4
• 化学式: C₅H₇Cl₃O
• 分子量: 189.469
• InChiKey: ZDHJZOAADBIHAQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  9
• 可旋转键数：
  2
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  3,3-dichloro-2,2-dimethylpropionyl chloride 生成 3,3-Dichloro-2,2-dimethylpropanoyl cyanide
  参考文献：
  名称：

  KRANZ, ECKART;SANTEL, HANS-JOACHIM;LUSSEN, KLAUS;SCHMIDT, ROBERT R.

  摘要：

  DOI：
• 作为产物：
  描述：

  三甲基乙酰氯 生成 3,3-dichloro-2,2-dimethylpropionyl chloride
  参考文献：
  名称：

  MIYAZAWA, KENICHI;FURUSAWA, OSAMU

  摘要：

  DOI：

文献信息

• Herbicidal 3-isoxazolidinones and hydroxamic acids
  申请人：FMC Corporation

  公开号：US04405357A1

  公开（公告）日：1983-09-20

  Novel 3-isoxazolidinone compounds and novel hydroxamic acid intermediates from which they are prepared exhibit herbicidal activity to grassy and broad-leaf plant species while leaving legumes, especially soybeans, unaffected. The preparation and herbicidal activity of the compounds is exemplified.

  新型3-异噁唑烷酮化合物和新型羟羧酸中间体表现出对禾本科和阔叶植物种类的除草活性，同时不影响豆科植物，特别是大豆。这些化合物的制备和除草活性得到了示范。
• Scavenger assisted combinatorial process for preparing libraries of amides, carbamates and sulfonamides
  申请人：ELI LILLY AND COMPANY

  公开号：EP0825164A2

  公开（公告）日：1998-02-25

  This invention relates to a novel solution phase process for the preparation of amide, carbamate, and sulfonamide combinatorial libraries. These libraries have utility for drug discovery and are used to form wellplate components of novel assay kits.

  这项发明涉及一种用于制备酰胺、碳酸酯和磺酰胺组合库的新型溶液相过程。这些库在药物发现中具有实用价值，并用于形成新型检测套件的微孔板组件。
• [EN] LAZOLIDINE DERIVATIVES AS HERBICIDAL AGENTS<br/>[FR] DERIVES D'AZOLIDINE EN TANT QU'AGENTS HERBICIDES
  申请人：BAYER CROPSCIENCE AG

  公开号：WO2005000824A1

  公开（公告）日：2005-01-06

  Novel azolidine derivatives of the formula (I) wherein R1 represents halogen, alkyl, alkoxy, haloalkyl, haloalkoxy, haloalkylthio or haloalkylene-dioxy, m represents 0, 1, 2, 3, 4 or 5, the R1 substituents are identical or different each other, when m represents 2, 3, 4 or 5, R2 represents alkyl, X represents alkylidene, oxygen atom or sulfur atom, and A represents one of the groups described in the specification and their use as herbicides.

  (I)式的新型氮杂环丙烷衍生物，其中R1代表卤素、烷基、烷氧基、卤代烷基、卤代烷氧基、卤代烷硫基或卤代烷二氧基，m代表0、1、2、3、4或5，R1取代基彼此相同或不同，当m代表2、3、4或5时，R2代表烷基，X代表烷基烯、氧原子或硫原子，A代表规范中描述的一种基团，以及它们作为除草剂的用途。
• Preparation of novel selenapenams and selenacephems by nucleophilic and radical chemistry involving benzyl selenides
  作者：Michael W. Carland、Robyn L. Martin、Carl H. Schiesser

  DOI：10.1039/b409242b

  日期：——

  2,2a-Dihydro-1H,8H-azeto[2,1-b][1,3]benzoselenazin-1-one (12), 5-selena-1-azabicyclo[4.2.0]oct-3-en-8-one (13), ethyl 1-aza-7-oxo-4-selenabicyclo[3.2.0]heptane-2-carboxylate (16), and benzoselenopenem (33) can be prepared in 39–85% yield through the intramolecular homolytic substitution of aryl, vinyl or alkyl radicals at the selenium atom in suitably-substituted 4-benzylseleno-β-lactams, or through intramolecular nucleophilic substitution by the benzylseleno moiety in 4-halo-β-lactam precursors. Application of this chemistry to the preparation of optically active selenium-containing analogues of β-lactam antibiotics is also detailed.

  2,2a-二氢-1H,8H-氮杂[2,1-b][1,3]苯硒嗪-1-酮（12）、5-硒-1-氮杂双环[4.2.0]辛-3-烯-8-酮（13）、乙基1-氮杂-7-氧-4-硒双环[3.2.0]庚-2-羧酸酯（16）和苯并硒烯酮（33）可以通过适宜取代的4-苯基硒-β-内酰胺中的硒原子上对芳基、烯基或烷基自由基的分子内均裂替换，或者通过4-卤代-β-内酰胺前体中苄基硒基团的分子内亲核替换，得到39～85%的产率。此外，文中还详细描述了这种化学方法在制备光学活性含硒β-内酰胺抗生素类似物方面的应用。
• Mono- and di-acylphosphine oxides
  申请人：Ciba-Geigy Corporation

  公开号：US05218009A1

  公开（公告）日：1993-06-08

  Compounds of the formula I ##STR1## in which at least one of the radicals R.sub.1, R.sub.2 and R.sub.3 is a substituted alkyl radical or cycloalkyl radical, or R.sub.1 and R.sub.2 together with the phosphorus atom form a monocyclic or tricyclic ring, are effective photoinitiators for the photopolymerization of ethylenically unsaturated compounds.

  公式I的化合物 ##STR1## 其中至少一个基团R.sub.1、R.sub.2和R.sub.3是取代烷基基团或环烷基团，或R.sub.1和R.sub.2与磷原子一起形成单环或三环的环，对于乙烯基不饱和化合物的光聚合是有效的光引发剂。