phenyl tetramethylphosphorodiamidite | 26546-75-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: phenyl tetramethylphosphorodiamidite
• 英文别名: phenyl tetramethyldiamidophosphite；Phenyl-tetramethylphosphorodiamidit；Phosphorodiamidous acid, tetramethyl-, phenyl ester；N-[dimethylamino(phenoxy)phosphanyl]-N-methylmethanamine
• CAS: 26546-75-8
• 化学式: C₁₀H₁₇N₂OP
• 分子量: 212.232
• InChiKey: PQJRTJAQBXWJRR-UHFFFAOYSA-N

物化性质

• 沸点：
  127 °C(Press: 10 Torr)
• 密度：
  1.1324 g/cm3

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  14
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  15.7
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  phenyl tetramethylphosphorodiamidite 在 ammonium sulfate 、 sulfur 作用下， 以 苯 为溶剂， 反应 2.0h， 生成 hexahydro-1,3-bis(trimethylsilyl)-2-phenoxy-1,3,2-diazaphosphorine 2-sulfide
  参考文献：
  名称：

  Kurochkin, V. V.; Zavalishina, A. I.; Orzhekovskaya, E. I., Journal of general chemistry of the USSR, 1987, vol. 57, p. 265 - 274

  摘要：

  DOI：
• 作为产物：
  描述：

  三(二甲胺基)膦 、 苯酚 以 1,4-二氧六环 为溶剂， 反应 36.0h， 以77%的产率得到phenyl tetramethylphosphorodiamidite
  参考文献：
  名称：

  Dismutation of Diamidoarylphosphites

  摘要：

  Some examples of spontaneous dismutation of diamidoarylphosphites in different solvents were studied, and features of the process were revealed.

  DOI：

  10.1080/714040960

文献信息

• Dismutation of arylene phosphorodiamidites: Specific features and aspects of preparative use
  作者：E. N. Rasadkina、P. V. Slitikov、E. E. Nifant’ev

  DOI：10.1134/s1070363206020046

  日期：2006.2

  The dismutation ofarylene phosphorodiamidites derived from the simplest phenols and naphthols and of their dibasic analogs was studied. The main regular trends of this process and the limits of its synthetic applicability were determined.
• Pentacovalent phosphorus. II. Reactions of dione and lactone dimers of dimethylketene with trivalent phosphorous acid amides
  作者：Wesley G. Bentrude、W. Delmar Johnson、Wajid A. Khan

  DOI：10.1021/jo00969a025

  日期：1972.2
• Nifant'ev, E. E.; Zavalishina, A. I.; Kurochkin, V. V., Journal of general chemistry of the USSR, 1985, vol. 55, # 9, p. 1803 - 1808
  作者：Nifant'ev, E. E.、Zavalishina, A. I.、Kurochkin, V. V.、Smirnova, E. I.、Borisenko, A. A.

  DOI：——

  日期：——
• Cyclophosphorylation of polyphenols by diamidoarylphosphites
  作者：Vera I Maslennikova、Roman V Merkulov、Maria V Dyagileva、Larisa K Vasyanina、Konstantin A Lyssenko、Mikhail Yu Antipin、Dirk Weber、Ingmar Bauer、Wolf D Habicher、Eduard E Nifantyev

  DOI：10.1016/s0040-4020(03)00111-x

  日期：2003.3

  It was found that the cyclophosphorylation of polyphenols by diamidoarylphosphites proceeds via the rupture of only one P-N bond and one P-O bond, the second P-N bond remaining intact, It is supposed that the unusual lack of reactivity of the P-N bond is due to the spatial arrangement of the amido group with respect to the reaction site in phosphorylated intermediates 5. (C) 2003 Published by Elsevier Science Ltd.
• NIFANTEV EH. E.; ZAVALISHINA A. I.; KUROCHKIN V. V.; NIKOLAEVA E. V.; VAS+, ZH. OBSHCH. XIMII, 1981, 51, HO 2, 474-475
  作者：NIFANTEV EH. E.、 ZAVALISHINA A. I.、 KUROCHKIN V. V.、 NIKOLAEVA E. V.、 VAS+

  DOI：——

  日期：——