2-(3,5-difluorophenyl)-5-propyl-1,3-dioxane | 202476-46-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-(3,5-difluorophenyl)-5-propyl-1,3-dioxane
• CAS: 202476-46-8
• 化学式: C₁₃H₁₆F₂O₂
• 分子量: 242.266
• InChiKey: BOLVIBIHTXZVFX-UHFFFAOYSA-N

物化性质

• 沸点：
  286.9±40.0 °C(Predicted)
• 密度：
  1.125±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  17
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.54
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  2-(3,5-difluorophenyl)-5-propyl-1,3-dioxane 在 正丁基锂 、 碘 作用下， 以 四氢呋喃 为溶剂， 以95.6 %的产率得到2-(3,5-difluoro-4-iodophenyl)-5-propyl-1,3-dioxane
  参考文献：
  名称：

  一类含杂原子六元脂环的含氟铁电液晶分子及其合成方法

  摘要：

  本发明公开了一类含杂原子六元脂环的含氟铁电液晶分子及其合成方法，所述含氟铁电液晶分子合成方法简单，原料易得，并且获得的含氟铁电液晶分子能够呈现出铁电向列相，具有较宽的铁电向列相温度范围、超高的介电常数、超低的驱动电压、强极化程度，超快电场响应，以及强的非线性光学响应。本发明合成的化合物是一种变革性的液晶材料，应用前景广阔。

  公开号：

  CN115960074A
• 作为产物：
  描述：

  1-溴-3,5-二氟苯 在 对甲苯磺酸 、 magnesium 作用下， 以 四氢呋喃 、 甲苯 为溶剂， 反应 7.0h， 生成 2-(3,5-difluorophenyl)-5-propyl-1,3-dioxane
  参考文献：
  名称：

  Enantiotropic ferroelectric nematic phase in a single compound

  摘要：

  报告介绍了高极性铁电向列液晶的设计、合成和物理化学特性。该化合物表现出各向异性的 NF 相，是第一个具有这种特性的实例。

  DOI：

  10.1039/d3cc04296k

文献信息

• Phenyldioxane derivatives, liquid crystal compositions, and liquid crystal display elements
  申请人：Chisso Corporation

  公开号：EP0819685A1

  公开（公告）日：1998-01-21

  There is provided an electrically and chemically stable liquid crystalline compound which exhibits a significantly large value of De and a high voltage holding ratio. The compound is a phenyldioxane derivative represented by formula (1): wherein R represents a C1-C20 alkyl group; each of n1 and n2 represents 0 or 1; each of Q1 through Q6 represents a hydrogen atom, a fluorine atom, or a chlorine atom, provided that Q3 is a fluorine atom or a chlorine atom when n2 is 0, and that at least one of Q1 and Q3 is a fluorine atom or a chlorine atom when n2 is 1; each of Za and Zb represents a single bond, -COO-, or -CF2O-; Zc represents a single bond or -CH2CH2-; Y represents a hydrogen atom, a halogen atom, or a C1-C5 halogenated alkyl group in which one or more non-adjacent methylene groups may be replaced by oxygen atoms or sulfur atoms; and each of the elements that constitute the compound may comprise isotopes of the element. The compound also exhibits excellent compatibility with previously known liquid crystalline compounds, and is advantageously used for low voltage driving of liquid crystal displays for TFTs. There are also provided liquid crystal compositions comprising the compound, as well as liquid crystal display elements constructed of the compositions.

  提供了一种电学和化学稳定的液晶化合物，其具有显着大的De值和高的耐压比。该化合物是一种由式（1）表示的苯二氧杂环丙烷衍生物：其中R代表一个C1-C20烷基基团；n1和n2中的每一个代表0或1；Q1至Q6中的每一个代表氢原子、氟原子或氯原子，条件是当n2为0时，Q3是氟原子或氯原子，当n2为1时，Q1和Q3中至少一个是氟原子或氯原子；Za和Zb中的每一个代表单键，-COO-或-CF2O-；Zc代表单键或-CH2CH2-；Y代表氢原子、卤素原子或一个C1-C5卤代烷基基团，其中一个或多个非相邻亚甲基基团可被氧原子或硫原子替代；构成该化合物的每个元素可能包括该元素的同位素。该化合物还表现出与先前已知的液晶化合物具有良好的兼容性，并且可优势用于TFT液晶显示器的低电压驱动。还提供了包含该化合物的液晶组合物，以及由这些组合物构建的液晶显示元件。
• Phenyldioxane derivatives, liquid crystal compositions, and liquid
  申请人：Chisso Corporation

  公开号：US05858272A1

  公开（公告）日：1999-01-12

  There is provided an electrically and chemically stable liquid crystalline compound which exhibits a significantly large value of De and a high voltage holding ratio. The compound is a phenyldioxane derivative represented by formula (1): ##STR1## wherein R represents a C1-C20 alkyl group; each of n1 and n2 represents 0 or 1; each of Q.sub.1 through Q.sub.6 represents a hydrogen atom, a fluorine atom, or a chlorine atom, provided that Q.sub.3 is a fluorine atom or a chlorine atom when n2 is 0, and that at least one of Q.sub.1 and Q.sub.3 is a fluorine atom or a chlorine atom when n2 is 1; each of Za and Zb represents a single bond, --COO--, or --CF.sub.2 O--; Zc represents a single bond or --CH.sub.2 CH.sub.2 --; Y represents a hydrogen atom, a halogen atom, or a C1-C5 halogenated alkyl group in which one or more non-adjacent methylene groups may be replaced by oxygen atoms or sulfur atoms; and each of the elements that constitute the compound may comprise isotopes of the element. The compound also exhibits excellent compatibility with previously known liquid crystalline compounds, and is advantageously used for low voltage driving of liquid crystal displays for TFTs. There are also provided liquid crystal compositions comprising the compound, as well as liquid crystal display elements constructed of the compositions.

  提供一种电学和化学稳定的液晶化合物，其具有显著的De值和高电压保持比。该化合物是由式（1）表示的苯基二噁烷衍生物：##STR1## 其中R表示C1-C20烷基；n1和n2中的每一个表示0或1；Q.sub.1到Q.sub.6中的每一个表示氢原子、氟原子或氯原子，但当n2为0时，Q.sub.3表示氟原子或氯原子，而当n2为1时，Q.sub.1和Q.sub.3中至少一个表示氟原子或氯原子；Za和Zb中的每一个表示单键，--COO--或--CF.sub.2 O--；Zc表示单键或--CH.sub.2 CH.sub.2 --；Y表示氢原子、卤素原子或C1-C5卤代烷基，其中一个或多个非相邻的亚甲基团可以被氧原子或硫原子取代；化合物的组成元素中的每一个都可以包括元素的同位素。该化合物还与先前已知的液晶化合物具有良好的兼容性，并且可优选用于TFT液晶显示器的低电压驱动。还提供了包含该化合物的液晶组合物，以及由该组合物构建的液晶显示元件。
• Rapid, solvent-minimized and sustainable access to various types of ferroelectric-fluid molecules by harnessing mechano-chemical technology
  作者：Hiroya Nishikawa、Motonobu Kuwayama、Atsuko Nihonyanagi、Barun Dhara、Fumito Araoka

  DOI：10.1039/d3tc02212a

  日期：——

  develop state-of-the-art device applications, effective preparation of various NF molecules is essential. Herein, to expand the NFLC molecular library, we implemented a mechanochemical (MC) technique for the production of LCs, demonstrating its high synthetic compatibility with NF/SmAFLCs. Chemical building blocks with high polarity can be bonded one by one through various ball-milling MC reactions

  近年来，铁电流体，例如铁电向列液晶（N F LC）和铁电近晶A液晶（SmA F LC），由于其优异的极化特性（例如介电常数、极化率和介电常数）而引起了巨大的基础和实际兴趣。非线性光学系数）。为了深入了解这种新兴铁电相的物理基础并开发最先进的器件应用，有效制备各种 NF分子至关重要。在此，为了扩展 NF LC分子库，我们实施了机械化学 (MC) 技术来生产 LC，证明了其与 NF / SmA的高度合成兼容性F LC。高极性的化学构件可以通过各种球磨MC反应逐一键合，从而快速获得NF LC分子、一系列DIO、RM734、UUZU和BIOTN，在2.7-7小时内高产率4-8 个步骤。对于一种新的 DIO 变体，其中末端烷基链被完全去除，我们首次发现了从各向同性液体到 SmA F相的直接相变。此外，使用正向上负向下（PUND）方法评估了SmA F相中的高度双稳态极化记忆（∼5.2 μC cm -2
• Synthesis and Properties of Novel Liquid Crystalline Compounds having a Difluoromethyleneoxy Moiety as a Linkage Group
  作者：Shuichi Matsui、Tomoyuki Kondo、Kouki Sago

  DOI：10.1080/15421400490434919

  日期：2004.1

  Novel liquid crystal compounds having a difluoromethyleneoxy group as a linkage group have been prepared by the new synthetic method using dibromo-difluoromethane in good yield. From. the results of physical property measurements; i.e., transition temperature, dielectric anisotropy (Deltaepsilon), birefringence (Deltan) and viscosity, it becomes obvious that the derivatives having 3,5-Difluorophenyl group at the carbon side of difluoramethyleneoxy group ((1) under bar) have high dielectric anisotropy and low viscosity, and the derivatives having 1, 4-cyclohexylene group at the carbon side of difluoromethyleneoxy group ((2) under bar) have good balance of their physical properties. Moreover, (1) under bar and (2) under bar indicate high voltage holding ratio. Therefore, a novel series of the compounds having a difluoromethyleneoxy linkage group is an eminently suitable material that can lower driving voltage and achieve quicker response time of the AM-LCDs.
• LIQUID CRYSTAL MEDIUM, OPTICAL DEVICE, AND LIQUID CRYSTAL COMPOUND
  申请人：JNC CORPORATION

  公开号：US20160002536A1

  公开（公告）日：2016-01-07

  A liquid crystal medium having stability to heat, light and so forth, a wide liquid crystal phase temperature range, a low driving voltage and a small permittivity and exhibiting an optically isotropic liquid crystal phase is described. An optical device or the like having a short response time, a large contrast ratio, a low driving voltage and a small permittivity is also described. The liquid crystal composition contains an achiral component (T) and a chiral agent, and exhibits an optically isotropic liquid crystal phase. The achiral component (T) includes at least one compound represented by formula (1): wherein, for example, R 1 is alkyl having 1 to 12 carbons, A 1 and A 2 are 1,4-phenylene, Z 1 and Z 2 are single bonds, Z 3 is —COO— or —CF 2 O—, L 11 is hydrogen, fluorine or chlorine, Y 1 is fluorine, chlorine, —CF 3 or —OCF 3 , n1 and n2 are each independently 0 or 1, and n1+n2≧1.