Tetradecanoic acid, ester with 1,2,3-propanetriol | 11140-02-6

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: Tetradecanoic acid, ester with 1,2,3-propanetriol
• 英文别名: propane-1,2,3-triol;tetradecanoic acid
• CAS: 11140-02-6
• 化学式: C17H36O5
• 分子量: 320.5
• InChiKey: DGPCSURYVBYWAT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  22
• 可旋转键数：
  14
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.94
• 拓扑面积：
  98
• 氢给体数：
  4
• 氢受体数：
  5

文献信息

• MEDICINAL PREPARATION
  申请人：TORAY INDUSTRIES, INC.

  公开号：EP1787661A1

  公开（公告）日：2007-05-23

  A pharmaceutical preparation has a ligand structure specifically recognizing a target site and an amphiphilic compound having a hydrophobic or amphiphilic group. The pharmaceutical preparation employs an amphiphilic compound of specific structure obtained by introducing a chained hydrophilic group with an appropriate flexibility, and thus becomes a fine particle suited for drug targeting. The pharmaceutical preparation is expected to give a prolonged pharmacological effect. A particulate preparation exhibiting a remarkable site targeting property can be formed. Further, according to the selection of matrix forming material, the drug releasing property can be controlled.

  一种药物制剂具有特异性识别靶位点的配体结构和具有疏水或两性亲和性基团的两性化合物。该药物制剂采用通过引入具有适当柔韧性的链状亲水基团获得的特定结构的两性化合物，因此成为适用于药物靶向的细颗粒。 预计该药物制剂将产生持久的药理效应。可以形成具有显著靶向性能的颗粒制剂。此外，根据基质形成材料的选择，可以控制药物释放性能。
• Clear antiperspirants and deodorants made with siloxane-based polyamides
  申请人：——

  公开号：US20020051758A1

  公开（公告）日：2002-05-02

  Clear antiperspirant and/or deodorant compositions, especially clear sticks having good structural integrity, can be formed by incorporating at least 8% by weight based on the total weight of the composition of a selected siliconized polyamide into a product formulated with at least one silicone material and at least one non-silicone emollient. The siliconized polyamides have the silicone portion in the acid side of the polyamide and are selected so that: (a) the degree of polymerization in the silicone portion is in the range of 12-18; (b) the average molecular weight of the siliconized polyamide is at least 50,000 daltons with at least 95% of the polyamide having a molecular weight greater than 10,000 as measured by size exclusion chromatography; and (c) the polydispersity is less than 20.

  清透的止汗剂和/或除臭剂配方，尤其是具有良好结构完整性的清透固体产品，可以通过将至少8%的选择性硅化聚酰胺按照配方总重量计入产品中来形成，该产品配方中包含至少一种硅材料和至少一种非硅乳化剂。硅化聚酰胺的硅部分位于聚酰胺的酸侧，并且选择这样的硅化聚酰胺：（a）硅部分的聚合度在12-18范围内；（b）硅化聚酰胺的平均分子量至少为50,000道尔顿，其中至少95%的聚酰胺具有大于10,000的分子量，通过尺寸排除色谱法测量；（c）聚分散度小于20。
• Pharmaceutical composition and its use
  申请人：Takeda Chemical Industries, Ltd.

  公开号：EP0094157A1

  公开（公告）日：1983-11-16

  A pharmaceutical composition containing a hydrophilic drug which is poorly absorbable through the gastrointestinal tract and cyclodextrin brings an increased absorbability of the drug into the mammalian body when administered non-oral or non-injection.

  一种含有亲水性药物的药物组合物，这种药物通过胃肠道的吸收性较差，而环糊精在非口服或非注射给药的情况下，可增加药物在哺乳动物体内的吸收性。
• Lubricating insolubiliser for paper coating compositions
  申请人：SEQUA CHEMICALS INC.

  公开号：EP0361941A2

  公开（公告）日：1990-04-04

  Paper coating compositions contain at least one pigment, at least one binder, and as an insolubiliser for the binder, the product of reacting glyoxal with a polyhydroxyl substituted ester of a fatty acid and then with a polyol.

  纸张涂料组合物含有至少一种颜料、至少一种粘合剂，以及作为粘合剂不溶解剂的乙二醛与脂肪酸的多羟基取代酯再与多元醇反应的产物。
• Process for producing saccharide fatty acid monoesters
  申请人：LION CORPORATION

  公开号：EP0413307A1

  公开（公告）日：1991-02-20

  A process for producing a saccharide fatty acid monoester comprises reacting an immobilized thermostable lipase on a mixture comprising: (A) one or more of acyl donors selected from saturated and unsaturated fatty acids with 6 to 22 carbon atoms, lower alkyl esters of said fatty acids and glycerol esters of said fatty acids, (B) one or more of saccharides selected from monosaccharides with 5 to 7 carbon atoms, disaccharides composed of hexose, sugar alcohols with 4 to 6 carbon atoms, ethers of monosaccharides with 5 to 7 carbon atoms and monohydric alcohols and ethers of disaccharides composed of hexose and monohydric alcohols, and (C) one or more of alcohols selected from secondary alcohols and tertiary alcohols.

  一种生产糖类脂肪酸单酯的工艺包括将固定化的恒温脂肪酶与一种混合物反应，该混合物包括 (A) 一种或多种选自具有 6 至 22 个碳原子的饱和和不饱和脂肪酸、所述脂肪酸的低级烷基酯和所述脂肪酸的甘油酯的酰基供体、 (B) 一种或多种选自 5 至 7 个碳原子的单糖、由己糖组成的二糖、4 至 6 个碳原子的糖醇、5 至 7 个碳原子的单糖和一元醇的醚以及由己糖和一元醇组成的二糖的醚的糖类，以及 (C) 选自仲醇和叔醇的一种或多种醇。