Methyl (3-hydroxypropyldisulfanyl)formate | 1176834-43-7

• 分子结构分类: 有机化合物 - 有机硫化合物 - 硫代羰基化合物
• 英文名称: Methyl (3-hydroxypropyldisulfanyl)formate
• 英文别名: methyl (3-hydroxypropyldisulfanyl)formate
• CAS: 1176834-43-7
• 化学式: C₅H₁₀O₃S₂
• 分子量: 182.265
• InChiKey: LECGJJROBCEMHA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.8
• 重原子数：
  10
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  97.1
• 氢给体数：
  1
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  三光气 、 Methyl (3-hydroxypropyldisulfanyl)formate 以 二氯甲烷 为溶剂， 生成 3-[(methoxycarbonyl)disulfanyl]-1-propanyl chloroformate
  参考文献：
  名称：

  An improved synthesis of releasable luciferin–CPP conjugates

  摘要：

  We have improved the synthesis of a previously published luciferin-linker, used in an assay enabling rapid real-time quantification of luciferin-CPP conjugate uptake and cytosolic cargo release. We also present the synthesis of a new luciferin-linker with the same conjugation ability. Both luciferin-linkers are now available via an efficient one-pot procedure. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2009.06.038
• 作为产物：
  描述：

  3-巯基-1-丙醇 、 氯化甲氧羰基硫 以 二氯甲烷 为溶剂， 生成 Methyl (3-hydroxypropyldisulfanyl)formate
  参考文献：
  名称：

  An improved synthesis of releasable luciferin–CPP conjugates

  摘要：

  We have improved the synthesis of a previously published luciferin-linker, used in an assay enabling rapid real-time quantification of luciferin-CPP conjugate uptake and cytosolic cargo release. We also present the synthesis of a new luciferin-linker with the same conjugation ability. Both luciferin-linkers are now available via an efficient one-pot procedure. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2009.06.038

文献信息

• An improved synthesis of releasable luciferin–CPP conjugates
  作者：Emelía Eiríksdóttir、Ülo Langel、Katri Rosenthal-Aizman

  DOI：10.1016/j.tetlet.2009.06.038

  日期：2009.8

  We have improved the synthesis of a previously published luciferin-linker, used in an assay enabling rapid real-time quantification of luciferin-CPP conjugate uptake and cytosolic cargo release. We also present the synthesis of a new luciferin-linker with the same conjugation ability. Both luciferin-linkers are now available via an efficient one-pot procedure. (C) 2009 Elsevier Ltd. All rights reserved.