N-cyclohexylpyrrolidine-1-carbothioamide | 15260-45-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯烷类
• 英文名称: N-cyclohexylpyrrolidine-1-carbothioamide
• CAS: 15260-45-4
• 化学式: C₁₁H₂₀N₂S
• mdl: MFCD03992051
• 分子量: 212.359
• InChiKey: FDXJZLFRULSTDC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  14
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.909
• 拓扑面积：
  47.4
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  N-cyclohexylpyrrolidine-1-carbothioamide 在 盐酸 作用下， 以 氯仿 、 异丙醇 为溶剂， 生成 1-Cyclohexyl-2-pyrrolidin-1-yl-1H-imidazole
  参考文献：
  名称：

  Nagarajan, K.; Arya, V. P.; George, T., Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 1982, vol. 21, # 10, p. 949 - 952

  摘要：

  DOI：
• 作为产物：
  描述：

  四氢吡咯 、 环己基异硫氰酸脂 以 乙腈 为溶剂， 反应 2.0h， 生成 N-cyclohexylpyrrolidine-1-carbothioamide
  参考文献：
  名称：

  A novel atom-efficient, one-pot synthesis of sulfonylguanidines and sulfamoylguanidines

  摘要：

  An expedient one-pot procedure for the atom-efficient production of a variety of sulfonylguanidines and sulfamoylguanidines under mild conditions is described. The route constitutes an important alternative to current methods. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2011.04.031

文献信息

• THIOUREA GROUP IV TRANSITION METAL CATALYSTS AND POLYMERIZATION SYSTEMS
  申请人：Dow Global Technologies LLC

  公开号：US20190202950A1

  公开（公告）日：2019-07-04

  Catalyst compositions and polymerization systems include at least one thiourea complex according to Formula (I): MQ a X 4-a (I) in which M is Ti, Zr, or Hf; a is 1 or 2; each group Q of the thiourea complex is a bidentate thiourea ligand bound to the metal center and having Formula (Ia), Formula (Ib), or Formula (Ic): (Formulas should be inserted here). In Formulas (Ia), (Ib), and (Ic), each group R 1 , R 2 , and R 3 is independently chosen from alkyl groups or aryl groups; each group Z 1 or Z 2 is independently chosen from alkylene groups. If a=2, groups R 1 of the two groups Q are optionally linked, or groups R 3 of the two groups Q are optionally linked. Each X is covalently bonded or coordinated to the metal center and is independently chosen from alkyl groups or halides. The polymerization systems may be configured to copolymerize ethylene and α-olefins.

  催化剂组合物和聚合体系包括至少一种符合以下公式(I)的硫脲配合物：MQaX4-a(I)，其中M为钛、锆或铪；a为1或2；硫脲配合物的每个Q基是与金属中心结合的双齿硫脲配体，具有公式(Ia)、公式(Ib)或公式(Ic)：（公式应在此处插入）。在公式(Ia)、(Ib)和(Ic)中，每个基团R1、R2和R3独立地选择自烷基或芳基；每个基团Z1或Z2独立地选择自亚烷基基团。如果a=2，则两个Q基团的R1基团可选择性地连接，或者两个Q基团的R3基团可选择性地连接。每个X与金属中心共价键合或配位，并且独立地选择自烷基或卤化物。聚合体系可能被配置为共聚合乙烯和α-烯烃。
• Thiourea group IV transition metal catalysts and polymerization systems
  申请人：Dow Global Technologies LLC

  公开号：US10968297B2

  公开（公告）日：2021-04-06

  Catalyst compositions and polymerization systems include at least one thiourea complex according to Formula (I): MQaX4-a (I) in which M is Ti, Zr, or Hf; a is 1 or 2; each group Q of the thiourea complex is a bidentate thiourea ligand bound to the metal center and having Formula (Ia), Formula (Ib), or Formula (Ic): (Formulas should be inserted here). In Formulas (Ia), (Ib), and (Ic), each group R1, R2, and R3 is independently chosen from alkyl groups or aryl groups; each group Z1 or Z2 is independently chosen from alkylene groups. If a=2, groups R1 of the two groups Q are optionally linked, or groups R3 of the two groups Q are optionally linked. Each X is covalently bonded or coordinated to the metal center and is independently chosen from alkyl groups or halides. The polymerization systems may be configured to copolymerize ethylene and α-olefins.

  催化剂组合物和聚合体系包括至少一种符合式(I)的硫脲络合物：MQaX4-a (I) 其中 M 是 Ti、Zr 或 Hf；a 是 1 或 2；硫脲络合物的每个基团 Q 是与金属中心结合的双齿硫脲配体，具有式 (Ia)、式 (Ib) 或式 (Ic)：(此处应插入公式）。在式(Ia)、(Ib)和(Ic)中，每个基团 R1、R2 和 R3 独立选自烷基或芳基；每个基团 Z1 或 Z2 独立选自亚烷基。如果 a=2，则两个基团 Q 的基团 R1 有选择地相连，或两个基团 Q 的基团 R3 有选择地相连。每个 X 都与金属中心共价键合或配位，并独立地选自烷基或卤化物。聚合系统可配置为乙烯和 α-烯烃的共聚物。
• NAGARAJAN, K.;ARYA, V. P.;GEORGE, T.;BHAT, G. A.;KULKARNI, Y. S.;SHENOY, +, INDIAN J. CHEM., 1982, 21, N 10, 949-952
  作者：NAGARAJAN, K.、ARYA, V. P.、GEORGE, T.、BHAT, G. A.、KULKARNI, Y. S.、SHENOY, +

  DOI：——

  日期：——
• [EN] THIOUREA GROUP IV TRANSITION METAL CATALYSTS AND POLYMERIZATION SYSTEMS<br/>[FR] CATALYSEURS THIOURÉE-MÉTAL DE TRANSITION DU GROUPE IV, ET SYSTÈMES DE POLYMÉRISATION
  申请人：DOW GLOBAL TECHNOLOGIES LLC

  公开号：WO2018063799A1

  公开（公告）日：2018-04-05

  Catalyst compositions and polymerization systems include at least one thiourea complex according to Formula (I): MQaX4-a (I) in which M is Ti, Zr, or Hf; a is 1 or 2; each group Q of the thiourea complex is a bidentate thiourea ligand bound to the metal center and having Formula (Ia), Formula (Ib), or Formula (Ic): (Formulas should be inserted here). In Formulas (Ia), (Ib), and (Ic), each group R1, R2, and R3 is independently chosen from alkyl groups or aryl groups; each group Z1or Z2 is independently chosen from alkylene groups. If a = 2, groups R1 of the two groups Q are optionally linked, or groups R3 of the two groups Q are optionally linked. Each X is covalently bonded or coordinated to the metal center and is independently chosen from alkyl groups or halides. The polymerization systems may be configured to copolymerize ethylene and α-olefins.
• A novel atom-efficient, one-pot synthesis of sulfonylguanidines and sulfamoylguanidines
  作者：Jos H.M. Lange、Stefan Verhoog、Hans J. Sanders、Arnold van Loevezijn、Chris G. Kruse

  DOI：10.1016/j.tetlet.2011.04.031

  日期：2011.6

  An expedient one-pot procedure for the atom-efficient production of a variety of sulfonylguanidines and sulfamoylguanidines under mild conditions is described. The route constitutes an important alternative to current methods. (C) 2011 Elsevier Ltd. All rights reserved.

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