spirodioxole-2,1'-adamantane> | 77377-08-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并间二氧杂环戊烯类
• 英文名称: spirodioxole-2,1'-adamantane>
• 英文别名: adamantylidenecatechol；spiro[benzo[1,3]dioxole-2,1'-adamantane]；Spiro[1,3-benzodioxole-2,2a(2)-tricyclo[3.3.1.13,7]decane]；spiro[1,3-benzodioxole-2,2'-adamantane]
• CAS: 77377-08-3
• 化学式: C₁₆H₁₈O₂
• 分子量: 242.318
• InChiKey: YHVFTCXOFOYLEO-UHFFFAOYSA-N

物化性质

• 沸点：
  355.9±17.0 °C(Predicted)
• 密度：
  1.24±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.9
• 重原子数：
  18
• 可旋转键数：
  0
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.62
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  spirodioxole-2,1'-adamantane> 在 溴 作用下， 以 四氯化碳 为溶剂， 反应 0.5h， 以48%的产率得到4,5-dibromo-(adamantylidene)catechol
  参考文献：
  名称：

  Cyclodextrin Dimers as Cleavable Carriers of Photodynamic Sensitizers

  摘要：

  Several phthalocyanines carrying hydrophobic components have been synthesized and shown to bind to a group of cyclodextrin dimers with a carbon-carbon double bond in the linker. The complexes are soluble in water. On irradiation in the presence of oxygen, the singlet oxygen produced cleaves the olefinic linkers in the complexes, resulting in precipitation of the sensitizers. This process concentrates the sensitizers in the light beam, a process that has useful potential in photodynamic therapy.

  DOI：

  10.1021/ja011709o
• 作为产物：
  描述：

  金刚烷酮 、 邻苯二酚 在 对甲苯磺酸 作用下， 以 苯 为溶剂， 反应 22.0h， 以84%的产率得到spirodioxole-2,1'-adamantane>
  参考文献：
  名称：

  Cyclodextrin Dimers as Cleavable Carriers of Photodynamic Sensitizers

  摘要：

  Several phthalocyanines carrying hydrophobic components have been synthesized and shown to bind to a group of cyclodextrin dimers with a carbon-carbon double bond in the linker. The complexes are soluble in water. On irradiation in the presence of oxygen, the singlet oxygen produced cleaves the olefinic linkers in the complexes, resulting in precipitation of the sensitizers. This process concentrates the sensitizers in the light beam, a process that has useful potential in photodynamic therapy.

  DOI：

  10.1021/ja011709o

文献信息

• Takakis, Ioannis M.; Hadjimihalakis, Phaedon M.; Tsantali, Georgia G., Journal of Heterocyclic Chemistry, 1992, vol. 29, # 1, p. 123 - 128
  作者：Takakis, Ioannis M.、Hadjimihalakis, Phaedon M.、Tsantali, Georgia G.、Pilini, Helena

  DOI：——

  日期：——
• Takakis Ioannis M., Hadjimihalakis Phaedon M., Tsantali Georgia G., Pilin+, J. Heterocycl. Chem., 29 (1992) N 1, S 123-128
  作者：Takakis Ioannis M., Hadjimihalakis Phaedon M., Tsantali Georgia G., Pilin+

  DOI：——

  日期：——
• RESIN, RESIST COMPOSITION AND METHOD FOR PRODUCING RESIST PATTERN, AND COMPOUND
  申请人：SUMITOMO CHEMICAL COMPANY, LIMITED

  公开号：US20210191266A1

  公开（公告）日：2021-06-24

  Disclosed are a resin comprising a structural unit represented by formula (I), and a structural unit represented by formula (a1-1) and/or a structural unit represented by formula (a1-2), and a resist composition including this resin:
• Cyclodextrin Dimers as Cleavable Carriers of Photodynamic Sensitizers
  作者：Simon D. P. Baugh、Zhiwei Yang、David K. Leung、David M. Wilson、Ronald Breslow

  DOI：10.1021/ja011709o

  日期：2001.12.19

  Several phthalocyanines carrying hydrophobic components have been synthesized and shown to bind to a group of cyclodextrin dimers with a carbon-carbon double bond in the linker. The complexes are soluble in water. On irradiation in the presence of oxygen, the singlet oxygen produced cleaves the olefinic linkers in the complexes, resulting in precipitation of the sensitizers. This process concentrates the sensitizers in the light beam, a process that has useful potential in photodynamic therapy.