Highly Enantioselective Synthesis of γ-Hydroxy-α,β-acetylenic Esters by Asymmetric Alkyne Addition to Aldehydes
作者:Ge Gao、Qin Wang、Xiao-Qi Yu、Ru-Gang Xie、Lin Pu
DOI:10.1002/anie.200500469
日期:2006.1
Highly enantioselective catalytic methyl propiolate addition to both aromatic and aliphatic aldehydes
作者:Jian Huang、Siping Wei、Li Wang、Chun Zhang、Shuangxun Li、Pingxian Liu、Xi Du、Qin Wang
DOI:10.1016/j.tetasy.2016.03.009
日期:2016.6
The excellent catalytic effect on methyl propiolate addition to a wide range of aromatic and aliphatic aldehydes promoted by inexpensive and commercially available BINOL-based ligand is reported. The catalyst systems showed high yields and excellent enantioselectivities for aromatic aldehydes, and excellent yields and high enantioselectivities for aliphatic aldehydes. (C) 2016 Elsevier Ltd. All rights reserved.