N~3~-Acetyl-N-[2-(1H-imidazol-5-yl)ethyl]-beta-alaninamide | 159329-77-8

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: N~3~-Acetyl-N-[2-(1H-imidazol-5-yl)ethyl]-beta-alaninamide
• 英文别名: 3-acetamido-N-[2-(1H-imidazol-5-yl)ethyl]propanamide
• CAS: 159329-77-8
• 化学式: C₁₀H₁₆N₄O₂
• 分子量: 224.26
• InChiKey: MANGXSNMVUQETR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.1
• 重原子数：
  16
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  86.9
• 氢给体数：
  3
• 氢受体数：
  3

文献信息

• Apparatus for treatment of dermatological conditions
  申请人：Sonovia Limited

  公开号：EP2431075A1

  公开（公告）日：2012-03-21

  Disclosed is a method for treatment of the skin and associated kit. The method comprises applying to the skin a gel pad, gel cartridge or free flowing gel comprising a composition, wherein the composition comprises one or more anti-glycation agent, one or more anti-oxidant, one or more hyaluronan and a dermatologically acceptable excipient. The method further comprises application of ultrasound directly or indirectly to an area of skin where the gel pad, gel cartridge or free flowing gel has been applied, or as a pre-treatment to an area of skin to which the gel pad, gel cartridge or free flowing gel is to be applied.

  本发明公开了一种治疗皮肤的方法和相关试剂盒。该方法包括向皮肤施用凝胶垫、凝胶盒或自由流动凝胶，其中凝胶垫、凝胶盒或自由流动凝胶包含一种组合物，该组合物包含一种或多种抗糖化剂、一种或多种抗氧化剂、一种或多种透明质酸和皮肤病学上可接受的赋形剂。该方法还包括直接或间接对已使用凝胶垫、凝胶盒或自由流动凝胶的皮肤区域使用超声波，或作为对将要使用凝胶垫、凝胶盒或自由流动凝胶的皮肤区域的预处理。
• Organic LED light and ultrasonic transducer device in a flexible layer configuration with electrical stimulation
  申请人：CAREWEAR CORP.

  公开号：US11083619B2

  公开（公告）日：2021-08-10

  A flexible device having a layered structure for delivering electrical stimulation and one or both of light and ultrasound to a skin surface is provided. The device is flexible so as to form a non-planar contact surface against the skin surface, and includes one or both of (a) a flexible light emitter layer positioned between two flexible conductive layers that emits light when driven by a power source and (b) a flexible ultrasound emitter layer positioned between two flexible conductive layers that produces ultrasound when driven by a power source. The device also includes a flexible electrical stimulation layer that functions as an electrode and is configured to provide electrical stimulation when driven by a power source.

  本发明提供了一种具有分层结构的柔性装置，用于向皮肤表面提供电刺激以及光和超声波中的一种或两种刺激。该装置具有柔性，可形成与皮肤表面的非平面接触面，并包括以下两者中的一个或两个：(a) 位于两个柔性导电层之间的柔性光发射器层，在电源驱动下发射光；(b) 位于两个柔性导电层之间的柔性超声波发射器层，在电源驱动下产生超声波。该装置还包括一个柔性电刺激层，该层可用作电极，在电源驱动时可提供电刺激。
• PRODUIT DE COUPLAGE DE L'HISTAMINE ET D'UN ACIDE AMINE
  申请人：EXSYMOL S.A.M.

  公开号：EP0684944B1

  公开（公告）日：2001-07-25
• APPARATUS FOR TREATMENT OF DERMATOLOGICAL CONDITIONS
  申请人：Sonovia Holdings LLC

  公开号：EP1812110B1

  公开（公告）日：2013-06-19
• LIGHT AND ULTRASONIC TRANSDUCER DEVICE
  申请人：Sonovia Holdings LLC

  公开号：EP2968883A1

  公开（公告）日：2016-01-20