The present invention relates to novel, non-secosteroidal, sulfonate and sulfonamide functional diaryl compounds with vitamin D receptor (VDR) modulating activity that are less hypercalcemic than 1α,25 dihydroxy vitamin D3. These compounds are useful for treating bone disease and psoriasis.
[EN] VITAMIN D RECEPTOR MODULATORS<br/>[FR] MODULATEURS DU RECEPTEUR DE LA VITAMINE D
申请人:LILLY CO ELI
公开号:WO2005051898A3
公开(公告)日:2005-08-11
Vitamin D receptor modulators
申请人:Eli Lilly and Company
公开号:US07750184B2
公开(公告)日:2010-07-06
The present invention relates to novel, non-secosteroidal, sulfonate and sulfonamide functional diaryl compounds with vitamin D receptor (VDR) modulating activity that are less hypercalcemic than 1α,25 dihydroxy vitamin D3. These compounds are useful for treating bone disease and psoriasis.