cyclohexyl-H-phosphinate | 676329-47-8

• 分子结构分类: 有机化合物 - 有机氧化合物 - 有机含氧阴离子化合物
• 英文名称: cyclohexyl-H-phosphinate
• 英文别名: Phosphorosooxycyclohexane
• CAS: 676329-47-8
• 化学式: C₆H₁₁O₂P
• 分子量: 146.126
• InChiKey: OMORXSCROSLLDY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  9
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  烯丙苯 、 cyclohexyl-H-phosphinate 在 nickel dichloride 、 1,2-双(二苯基膦)乙烷 作用下， 以 甲苯 为溶剂， 反应 2.5h， 以40%的产率得到cyclohexyl-3-phenylpropyl-H-phosphinate
  参考文献：
  名称：

  锰催化和介导的芳基次膦酸酯及相关化合物的合成

  摘要：

  检查了H-次膦酸酯和相关化合物的自由基芳基化。找不到以空气为氧化剂的实际催化方法。但是，开发了一种廉价而稳健的方法，使用了催化性的Mn（II）作为自由基引发剂，而过量的Mn（IV）作为化学计量的氧化剂。使用这些条件，次膦基化合物的分子间和分子内芳基化具有广泛的范围，包括应用于合成P-杂环。完整介绍了该方法，并讨论了其局限性。

  DOI：

  10.1021/acs.joc.9b01239

文献信息

• METHOD FOR PRODUCING ALKENYL PHOSPHORUS COMPOUND
  申请人：MARUZEN PETROCHEMICAL CO., LTD.

  公开号：US20190263847A1

  公开（公告）日：2019-08-29

  Provided is a method for producing an alkenyl phosphorus compound which can produce an alkenyl phosphorus compound efficiently even with a smaller amount of a catalyst used than that used conventionally, and further which can maintain catalytic activity to produce an alkenyl phosphorus compound in high yield even at a larger reaction scale, and which can also be applied to quantity synthesis at an industrial scale using a conventional batch reactor or continuous reactor. A method for producing an alkenyl phosphorus compound, comprising: a step of reacting a compound represented by the following formula (1): [In formula (1), R 1 represents OR 3 or R 3 , R 2 represents OR 4 or R 4 , and R 3 and R 4 represent, for example, each independently a substituted or unsubstituted alkyl group.] with a compound represented by the following formula (2): R 5 —C≡CH  (2) [In formula (2), R 5 represents, for example, a hydrogen atom, or a substituted or unsubstituted alkyl group.] to produce the phosphorus alkenyl compound presented by at least any of the following formulas (3a) or (3b): [In formulas (3a) and (3b), R 1 and R 2 have the same meaning as defined in formula (1), and R 5 has the same meaning as defined in formula (2).], In which the compound represented by formula (1) is reacted with the compound represented by formula (2) using a transition metal catalyst, and a phosphorus oxo acid compound having an intramolecular P—H bond.

  提供的是一种生产烯基磷化合物的方法，该方法即使使用的催化剂量比传统方法少，也能高效地生产烯基磷化合物，而且能够在更大的反应规模下保持催化活性，以高收率生产烯基磷化合物，并且还可以在传统的批量反应器或连续反应器中进行工业规模的量产合成。 生产烯基磷化合物的方法包括以下步骤： 将以下式（1）所表示的化合物与以下式（2）所表示的化合物反应： 式（1）中，R1代表OR3或R3，R2代表OR4或R4，R3和R4例如各自独立地代表取代或未取代的烷基基团。 式（2）中，R5例如代表氢原子，或代表取代或未取代的烷基基团。 从而产生至少以下任一式（3a）或（3b）所表示的磷烯烃化合物： 式（3a）和（3b）中，R1和R2的含义与式（1）中定义的相同，R5的含义与式（2）中定义的相同。 其中，使用过渡金属催化剂和具有分子内P-H键的磷氧酸化合物使式（1）所表示的化合物与式（2）所表示的化合物反应。
• Extraction process for the selective removal of cobalt (II) from aqueous solutions
  申请人：CYANAMID CANADA INC.

  公开号：EP0046933A2

  公开（公告）日：1982-03-10

  Cobalt(II)-, nickel(II)-bearing aqueous solutions may be treated with an extractant comprising an organic-soluble phosphinic acid, or a salt thereof, to separate the cobalt(II) from the aqueous solution. Typical extraction techniques compatible with the instant process include liquid- liquid extraction employing either mixer settlers or columns, packed beds of supported extractants as in ion exchange, liquid membrane extraction and selective supported membrane extraction.

  含钴（II）、镍（II）的水溶液可以用萃取剂处理，萃取剂包括有机溶解的膦酸或其盐，以便从水溶液中分离出钴（II）。与本工艺兼容的典型萃取技术包括采用混合沉淀器或柱的液-液萃取、离子交换中的支撑萃取剂填料床、液膜萃取和选择性支撑膜萃取。
• Composite material
  申请人：AKZO N.V.

  公开号：EP0213681A1

  公开（公告）日：1987-03-11

  Composite consisting of a thermoplastic or thermosetting polymer or a vul­canized or non-vulcanized rubber containing yarns, cords and/or fabrics provided with a polyester-ester urethane as adhesive and which polyester-­ester urethane contains 30 to 80% by weight of blocks of ester units of a high-melting polyester and 70 to 20% by weight of blocks of ester units of a low-melting polyester which are linked together through ester groups and/or urethane groups. The melting-point of the polyester-ester urethane is at least 160°C and the melting-point of the low-melting polyester is not higher than 100°C.

  由热塑性或热固性聚合物或硫化橡胶或非硫化橡胶组成的复合材料，其中含有作为粘合剂的聚酯酯聚氨酯的纱线、绳索和/或织物，聚酯酯聚氨酯含有 30%至 80%（按重量计）的高熔点聚酯的酯单元块和 70%至 20%（按重量计）的低熔点聚酯的酯单元块，它们通过酯基和/或聚氨酯基团连接在一起。聚酯酯聚氨酯的熔点至少为 160°C，低熔点聚酯的熔点不高于 100°C。
• Novel organic phosphinic acid compounds
  申请人：CYANAMID CANADA INC.

  公开号：EP0236542A2

  公开（公告）日：1987-09-16

  The invention relates to novel organic phosphinic acid compounds of the formula wherein R₁ is 2,4,4-trimethylpentyl and R₂ is 2,4,4-tri­methylpentyl or cyclohexyl, and their use for the extraction of metals.

  本发明涉及式如下的新型有机膦酸化合物 其中 R₁ 是 2，4，4-三甲基戊基，R₂ 是 2，4，4-三甲基戊基或环己基，以及它们在金属萃取中的用途。
• Method for producing alkenyl phosphorus compound
  申请人：MARUZEN PETROCHEMICAL CO., LTD.

  公开号：US10479809B2

  公开（公告）日：2019-11-19

  Provided is a method for producing an alkenyl phosphorus compound which can produce an alkenyl phosphorus compound efficiently even with a smaller amount of a catalyst used than that used conventionally, and further which can maintain catalytic activity to produce an alkenyl phosphorus compound in high yield even at a larger reaction scale, and which can also be applied to quantity synthesis at an industrial scale using a conventional batch reactor or continuous reactor. A method for producing an alkenyl phosphorus compound, comprising: a step of reacting a compound represented by the following formula (1): [In formula (1), R1 represents OR3 or R3, R2 represents OR4 or R4, and R3 and R4 represent, for example, each independently a substituted or unsubstituted alkyl group.] with a compound represented by the following formula (2): [In formula (2), R5 represents, for example, a hydrogen atom, or a substituted or unsubstituted alkyl group.] to produce the phosphorus alkenyl compound presented by at least any of the following formulas (3a) or (3b): [In formulas (3a) and (3b), R1 and R2 have the same meaning as defined in formula (1), and R5 has the same meaning as defined in formula (2).], In which the compound represented by formula (1) is reacted with the compound represented by formula (2) using a transition metal catalyst, and a phosphorus oxo acid compound having an intramolecular P—H bond.

  本发明提供了一种生产烯基磷化合物的方法，与传统方法相比，该方法即使使用较少量的催化剂也能高效生产烯基磷化合物，而且即使在较大的反应规模下也能保持催化活性以高产率生产烯基磷化合物，该方法还可用于使用传统的间歇反应器或连续反应器进行工业规模的定量合成。 一种生产烯基磷化合物的方法，包括 使下式（1）代表的化合物反应的步骤： 式（1）中，R1 代表 OR3 或 R3，R2 代表 OR4 或 R4，R3 和 R4 例如各自独立地代表取代或未取代的烷基。 与下式（2）所代表的化合物： 式（2）中，R5 代表氢原子或取代或未取代的烷基。 生成至少由以下任何式子（3a）或（3b）表示的磷烯基化合物： [在式 (3a) 和 (3b) 中，R1 和 R2 与式 (1) 所定义的含义相同，R5 与式 (2) 所定义的含义相同、］ 其中，使用过渡金属催化剂使式（1）代表的化合物与式（2）代表的化合物以及具有分子内 P-H 键的氧化磷化合物反应。