trans-β-styrenesulphonyl azide | 80639-78-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: trans-β-styrenesulphonyl azide
• 英文别名: trans-β-styrenesulfonyl azide；(E)-N-diazo-2-phenylethenesulfonamide
• CAS: 80639-78-7
• 化学式: C₈H₇N₃O₂S
• 分子量: 209.228
• InChiKey: MIYNPRURCJJVIG-VOTSOKGWSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  14
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  56.9
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  trans-β-styrenesulphonyl azide 690.0 ℃ 、199.98 Pa 条件下， 以66.6%的产率得到苯乙腈
  参考文献：
  名称：

  苯烷基磺酰基叠氮化物和叠氮基2-苯乙基酯的热解。磺酰基硝烯的选择性以及磺酰基-和羰基-硝烯之间的对比

  摘要：

  Ph [CH 2 ] n SO 2 N 3的快速真空热解和溶液热解表明，在溶液中分子内加成苯基是优选的，条件是形成最多八元的杜马环，否则会产生侧链插入，在气相中，当n = 4,5而不是3时，则优先采用后者。当n = 3在990°C时可获得一些5,6,7,8-四氢喹啉，但叠氮基甲酸2-苯乙酯生成了单体四氢-1、3-恶嗪基[3,4- a ] azepin-2-one和4-苯基-恶唑烷酮，即使在990°C时也没有二氢环戊[ b ]吡啶。

  DOI：

  10.1039/c39810001087
• 作为产物：
  描述：

  反-β-苯乙烯磺酰氯 在 sodium azide 作用下， 以 水 、 丙酮 为溶剂， 生成 trans-β-styrenesulphonyl azide
  参考文献：
  名称：

  通过铱催化的N-吡咯烷基吲哚与有机叠氮化物的轻度C–H酰胺化反应直接获得7-氨基吲哚

  摘要：

  已经开发了Ir（III）催化的吲哚与有机叠氮化物反应的区域选择性直接C-7酰胺化反应。尽管其效率因N-导向基团的选择而变化，但N-吡咯烷醇在室温下在广泛的底物上最有效地进行所需的酰胺化反应。该反应是可扩展的，并且螯合基团的脱保护也很容易。

  DOI：

  10.1021/acs.orglett.6b00662

文献信息

• Synthesis and micro-/nanostructuring of surface-attached crosslinked antimicrobial and/or antibiofouling polymer networks
  申请人：Universitätsklinikum Freiburg

  公开号：EP2636693A1

  公开（公告）日：2013-09-11

  The present invention relates to substrates comprising a crosslinked network of covalently attached antimicrobial and/or antibiofouling polymers. The crosslinked network of antimicrobial and/or antibiofouling polymers acts highly efficiently against pathogens, e.g. bacteria and fungi. Both the antimicrobial and the antibiofouling cross-linked polymer networks are preferably better resistant to mechanical damage than simple surface-immobilized polymer monolayers. The antimicrobial and/or antibiofouling polymers of the crosslinked network are preferably obtained by ring opening metathesis polymerization (ROMP) and exhibit a molecular weight of more than 1,000 g mol-1, preferably of more than 10,000 or even 100,000 g mol-1. The crosslinked network of antimicrobial and/or antibiofouling polymers is preferably covalently attached to the surface of a substrate, e.g. an implant, a medical device, medical equipment or a (tissue-supporting) biomaterial, etc. The present invention is also directed to uses of crosslinked networks of antimicrobial and/or antibiofouling polymers as defined herein, e.g. for coating a surface of a substrate, and to methods therefore.

  本发明涉及由共价连接的抗菌和/或防污聚合物交联网络组成的基材。交联的抗菌和/或防污聚合物网络可高效对抗细菌和真菌等病原体。与简单的表面固定聚合物单层相比，抗菌和抗生物污染交联聚合物网络具有更好的抗机械损伤能力。交联网络中的抗菌和/或防污聚合物最好是通过开环偏析聚合（ROMP）获得，分子量大于 1,000 g mol-1，最好大于 10,000 或甚至 100,000 g mol-1。抗微生物和/或抗生物污染聚合物的交联网络最好共价连接到基质表面，例如植入物、医疗器械、医疗设备或（组织支撑）生物材料等。本发明还涉及本文定义的抗微生物和/或抗生物污垢聚合物交联网络的用途，例如用于基底表面涂层，以及相关方法。
• SURFACE MODIFIED SUBSTRATE
  申请人：Celgard LLC

  公开号：EP3858900A1

  公开（公告）日：2021-08-04

  The present invention relates to a surface modified substrate comprising: a surface modifying agent chemically bound to a substrate, the substrate is a textile substrate or a battery separator, the surface modifying agent comprising a substrate coupling component being a nitrene and/or a carbene precursor. A surface modified substrate comprising: a surface modifying agent chemically bound to a substrate, the substrate is a textile substrate, the surface modifying agent comprising a substrate coupling component being a nitrene and/or a carbene precursor. Furthermore, the present invention is possibly preferably directed to a surface modifying agent which comprises a styrene sulfonated nitrene monomer, polymer or polymer containing one or more nitrene functional groups, which are capable of chemically reacting via an insertion reaction into one or more carbon-hydrogen bonds on the surface of a polymeric or textile material in order to chemically attach a specific or desired chemical functionality to the surface of a polymeric or textile material.

  本发明涉及一种表面改性基材，包括：一种与基材化学结合的表面改性剂，基材为纺织基材或电池隔膜，表面改性剂包括基材偶联组分，该组分为腈和/或碳烯前体。 一种表面改性基材，包括：与基材化学结合的表面改性剂，基材为纺织基材，表面改性剂包括基材偶联组分，该组分为腈和/或碳烯前体。 此外，本发明可能优选涉及一种表面改性剂，它包括苯乙烯磺化的腈单体、聚合物或含有一个或多个腈官能团的聚合物，它们能够通过插入反应与聚合物或纺织材料表面的一个或多个碳-氢键发生化学反应，以便将特定或所需的化学官能团化学地附着在聚合物或纺织材料的表面上。
• Surface modifying agents, modified materials and methods
  申请人：Celgard, LLC

  公开号：US10240031B2

  公开（公告）日：2019-03-26

  The present invention relates to surface modifying agents for polymeric and/or textile materials, methods of making and/or using a surface modifying agent to modify and functionalize polymeric and/or textile materials, and/or methods of using surface modified or functionalized polymeric and textile materials, and/or products using or incorporating surface modified or functionalized polymeric and textile materials. For example, the surface modifying agent in precursor form can be styrene sulfonyl azide monomer, polymer or copolymer capable of undergoing a chemical reaction in the presence of heat or light to form one or more styrene sulfonated nitrene monomers, polymers or copolymers, which are capable of chemically reacting with the surface of a polymeric or textile material to endow a specific or desired chemical surface functionality to the surface of a polymeric or textile material. Furthermore, the present invention is possibly preferably directed to a surface modifying agent which comprises a styrene sulfonated nitrene monomer, polymer or polymer containing one or more nitrene functional groups, which are capable of chemically reacting via an insertion reaction into one or more carbon-hydrogen bonds on the surface of a polymeric or textile material in order to chemically attach a specific or desired chemical functionality to the surface of a polymeric or textile material.

  本发明涉及聚合物和/或纺织材料的表面改性剂，制造和/或使用表面改性剂对聚合物和/或纺织材料进行改性和功能化的方法，和/或使用表面改性或功能化聚合物和纺织材料的方法，和/或使用或结合表面改性或功能化聚合物和纺织材料的产品。例如，前体形式的表面改性剂可以是苯乙烯磺酰叠氮单体、聚合物或共聚物，能够在热或光的存在下发生化学反应，形成一种或多种苯乙烯磺化腈单体、聚合物或共聚物，它们能够与聚合物或纺织材料的表面发生化学反应，从而赋予聚合物或纺织材料的表面特定或所需的化学表面功能。此外，本发明最好还涉及一种表面改性剂，它包括苯乙烯磺化腈单体、聚合物或含有一个或多个腈官能团的聚合物，它们能够通过插入反应与聚合物或纺织材料表面的一个或多个碳-氢键发生化学反应，从而在聚合物或纺织材料表面附着特定或所需的化学官能团。
• Iridium-Catalyzed Intermolecular Amidation of sp³ C–H Bonds: Late-Stage Functionalization of an Unactivated Methyl Group
  作者：Taek Kang、Youngchan Kim、Donggun Lee、Zhen Wang、Sukbok Chang

  DOI：10.1021/ja501014b

  日期：2014.3.19

  Reported herein is the iridium-catalyzed direct amidation of unactivated sp(3) C-H bonds. With sulfonyl and acyl azides as the amino source, the amidation occurs efficiently under mild conditions over a wide range of unactivated methyl groups with high functional group tolerance. This procedure can be successfully applied for the direct introduction of an amino group into complex compounds and thus can serve as a powerful synthetic tool for late-stage C-H functionalization.
• Solution and flash vacuum pyrolysis of some 2,6-disubstituted .beta.-phenethylsulfonyl azides and of .beta.-styrenesulfonyl azide
  作者：Rudolph A. Abramovitch、Albert O. Kress、Kutten S. Pillay、W. Marshall Thompson

  DOI：10.1021/jo00212a013

  日期：1985.6