2-Decyloxy-benzaldehyd | 24083-14-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 2-Decyloxy-benzaldehyd
• 英文别名: decyloxybenzaldehyde；2-(Decyloxy)benzaldehyde；2-decoxybenzaldehyde
• CAS: 24083-14-5
• 化学式: C₁₇H₂₆O₂
• mdl: MFCD00427657
• 分子量: 262.392
• InChiKey: QWYIWOLZHRIGCX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.9
• 重原子数：
  19
• 可旋转键数：
  11
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.588
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2-Decyloxy-benzaldehyd 在 lithium aluminium tetrahydride 作用下， 生成 o-Decyloxy-benzylalkohol
  参考文献：
  名称：

  337.氨基氧基衍生物。第五部分.2-取代的4,6-二氨基-1,2-二氢-1-羟基-1,3,5-三嗪的一些O-醚

  摘要：

  DOI：

  10.1039/jr9650001829

文献信息

• POLYALDIMINE AND CURABLE POLYURETHANE COMPOSITION
  申请人：SIKA TECHNOLOGY AG

  公开号：US20180319922A1

  公开（公告）日：2018-11-08

  A polyaldimine of the formula (I) with advantageous properties in use as latent hardener for compositions including isocyanate groups, and compositions containing the polyaldimine of the formula (I) and at least one polyisocyanate and/or at least one polyurethane polymer containing isocyanate groups. The polyaldimine of the formula (I) is odourless, pH-neutral, liquid at room temperature, has low viscosity, has little sensitivity to heat and moisture, and is stable in storage together with isocyanates. It can provide odourless single-component polyurethane compositions which have good stability in storage and which do not produce bubbles when hardened in the presence of moisture, and which cause no problematic odour emissions, giving a hardened elastic material with good mechanical properties and surprisingly little tendency towards plasticizer migration.

  公式（I）的聚多醛具有优越的性能，在含有异氰酸基的组分中作为潜在的固化剂使用，并且组合物含有公式（I）的聚多醛和至少一种聚异氰酸酯和/或至少一种含有异氰酸基的聚氨酯聚合物。公式（I）的聚多醛在室温下呈液态，无气味，pH中性，粘度低，对热和湿度敏感性小，与异氰酸酯一起储存时稳定。它可以提供无气味的单组分聚氨酯组合物，其在储存中具有良好的稳定性，在存在湿度时硬化时不产生气泡，并且不会产生问题的气味排放，给出具有良好机械性能和惊人的塑化剂迁移倾向的硬化弹性材料。
• Arylethanol amine derivatives, their preparation and use in pharmaceutical compositions
  申请人：BEECHAM GROUP PLC

  公开号：EP0066351A1

  公开（公告）日：1982-12-08

  Compounds of formula (II); or a salt thereof; wherein R' is hydrogen or methyl: R2 is hydrogen or methyl; R3 is hydrogen, C1-12 C1-12 cycloalkyl, or benzyl optionally substituted with C1-6 alkyl, C1-6 alkoxy, or halogen, n is 1 or 2; and A is hydrogen, halogen, hydroxyl, C1-6 alkyl or C1-6 alkoxy; are useful in treating obesity, diabetes, or inflammation, or inhibiting platelet aggregation.

  式（II）化合物或其盐，其中 R' 是氢或甲基：R2 是氢或甲基；R3 是氢、C1-12 C1-12 环烷基或任选被 C1-6 烷基、C1-6 烷氧基或卤素取代的苄基，n 是 1 或 2；以及 A 是氢、卤素、羟基、C1-6 烷基或 C1-6 烷氧基；这些化合物可用于治疗肥胖症、糖尿病或炎症，或抑制血小板聚集。
• Secondary phenyl ethanol amines and their pharmaceutical use
  申请人：BEECHAM GROUP PLC

  公开号：EP0070134A1

  公开（公告）日：1983-01-19

  Compounds of formula (II): or salt thereof; wherein R1 is hydrogen or methyl, R2 is hydrogen or methyl, R3 is hydrogen, C1-12 straight or branched alkyl, C3-10 cycloalkyl, phenyl(C1-4)-alkyl or benzyl optionally substituted by C1-4 alkyl, C1-4 alkoxy or halogen; R4 is hydrogen, halogen, hydroxy, C1-4 alkyl or C1-4 alkoxy, R5 is hydrogen or fluorine, R6 is hydrogen or fluorine, R7 is halogen; and n is 1 or 2, have anti-obesity andior anti-hyperglycaemic activity.

  式(II)化合物 或其盐类；其中 R1 是氢或甲基 R2 是氢或甲基 R3 是氢、C1-12 直链或支链烷基、C3-10 环烷基、苯基（C1-4）-烷基或任选被 C1-4 烷基、C1-4 烷氧基或卤素取代的苄基； R4 是氢、卤素、羟基、C1-4 烷基或 C1-4 烷氧基、 R5 是氢或氟 R6 是氢或氟 R7 是卤素 n 为 1 或 2，具有抗肥胖和抗高血糖活性。
• Alicyclic phospholipase A2 inhibitors
  申请人：Bristol-Myers Company

  公开号：EP0629604A2

  公开（公告）日：1994-12-21

  Compounds of Formula I: wherein the bonds between C₂ and C3 and/or between C₄ and C₅ are unsaturated; X = COOH, H, F, Cl, Br, I, COOR'', CONH₂, COR''', CHO, CH₂OH, CH₂OR''', OH, OR''', CF₃, C1-6 alkyl, C1-6 alkenyl, C1-6 haloalkyl, NO₂, P(O)(OH)₂, SO₂H, or SO₃H; R = substituted or unsubstituted alkyl, aryl, arylalkyl, alkenyl, or arylalkenyl groups, with the proviso that each of these groups must have 6 or more carbons (preferably 6 to 30) and R cannot be R' = H or C1-6 alkyl; R'' = H, C1-6 alkyl, C(R³)₂OC(O)R⁴, CH₂CH₂NR⁵R⁶, CH₂CH₂CH₂NR⁵R⁶, CH₂C(O)N(R⁶)₂, or other groups yielding physiologically hydrolyzable esters; R''' = C1-6 alkyl; R³ = H, CH₃, C₂H₅, CH₃CH₂CH₂ (with R³'s being the same or different); R⁴ = C6-12 aryl, C1-7 linear, branched or cyclic alkyl, or C1-7 linear, branched or cyclic alkoxy; R⁵ = R⁶, or when linked with R⁶, is a C₃-C₆ cycloalkyl or a -CH₂CH₂OCH₂CH₂-group; and R⁶ = C1-3 alkyl; and pharmaceutically-acceptable salts thereof are effective phospholipase A₂ (PLA₂) inhibitors.

  式 I 的化合物： 其中 C₂ 与 C3 之间和/或 C₄ 与 C₅ 之间的键为不饱和键； X = COOH、H、F、Cl、Br、I、COOR''、CONH₂、COR'''、CHO、CH₂OH、CH₂OR'''、OH、OR'''、CF₃、C1-6 烷基、C1-6 烯基、C1-6 卤代烷基、NO₂、P(O)(OH)₂、SO₂H 或 SO₃H； R = 取代或未取代的烷基、芳基、芳烷基、烯基或芳烷烯基，但这些基团都必须具有 6 个或更多的碳原子（最好是 6 至 30 个），且 R 不能是 R' = H 或 C1-6 烷基； R''=H、C1-6 烷基、C(R³)₂OC(O)R⁴、CH₂CH₂NR⁵R⁶、CH₂CH₂CH₂NR⁵R⁶、CH₂C(O)N(R⁶)₂ 或其他可产生生理性水解酯的基团； R''' = C1-6 烷基； R³ = H、CH₃、C₂H₅、CH₃CH₂CH₂（R³'s 相同或不同）； R⁴ = C6-12 芳基，C1-7 直链、支链或环状烷基，或 C1-7 直链、支链或环状烷氧基； R⁵ = R⁶，或当与 R⁶ 连接时，为 C₃-C₆ 环烷基或-CH₂CH₂OCH₂CH₂基团；以及 R⁶ = C1-3 烷基； 及其药学上可接受的盐是有效的磷脂酶 A₂（PLA₂）抑制剂。
• Polyurea compositions and compounds for the preparation thereof
  申请人：Sawyer, Kenneth I.

  公开号：EP2289962A2

  公开（公告）日：2011-03-02

  The invention is directed to novel compounds that are used in the formation of polyurea compositions, including one-part and two-part polyurea compositions. The invention is also directed to polyureas formed from such compounds, cross-linked polyureas, and UV-stabilized polyureas.

  本发明涉及用于形成聚脲组合物（包括单组分和双组分聚脲组合物）的新型化合物。本发明还涉及由此类化合物形成的聚脲、交联聚脲和紫外线稳定聚脲。