1-bromo-3-chloro-1,1,3,3-tetrafluoropropane | 460-87-7

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 有机氟化物
• 英文名称: 1-bromo-3-chloro-1,1,3,3-tetrafluoropropane
• 英文别名: 1-bromo-3-chloro-1,1,3,3-tetrafluoro-propane；1-Brom-3-chlor-1,1,3,3-tetrafluor-propan
• CAS: 460-87-7
• 化学式: C₃H₂BrClF₄
• 分子量: 229.399
• InChiKey: IYZDWHRLNGZSAI-UHFFFAOYSA-N

物化性质

• 沸点：
  79 °C
• 密度：
  1.7890 g/cm3(Temp: 25 °C)

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  9
• 可旋转键数：
  2
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  1-bromo-3-chloro-1,1,3,3-tetrafluoropropane 在 氢氧化钾 、 四丁基氢氧化铵 作用下， 以83%的产率得到3-氯-1,1,3,3-四氟-1-丙烯
  参考文献：
  名称：

  Perfluoro-4-methyl-1,3-dioxole: a new monomer for high-Tg amorphous fluoropolymers

  摘要：

  A 4-Chloro-5-trifluoromethyl-2,2,4-trifluoro-1,3-dioxolane (1) was synthesised by reaction of CF2(OF)(2) with CF3-CH=CFCl; the elimination of HCl from (1) in basic conditions led to the formation of dioxole perfluoro-4-methyl-1,3-dioxole (2). Both these synthetic steps gave the corresponding product in high yield.A new synthetic route for the preparation of CF3-CH=CFCl, starting from CF2ClBr and CH2=CF2, together with some examples of polymerisation products obtained by reaction of dioxole (2) with fluoroolefins are also reported. (C) 2003 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.jfluchem.2003.10.009
• 作为产物：
  描述：

  二氟一氯溴甲烷 、 偏氟乙烯 在 二叔丁基过氧化物 作用下， 110.0 ℃ 、2.03 MPa 条件下， 反应 8.0h， 以62%的产率得到1-bromo-3-chloro-1,1,3,3-tetrafluoropropane
  参考文献：
  名称：

  Perfluoro-4-methyl-1,3-dioxole: a new monomer for high-Tg amorphous fluoropolymers

  摘要：

  A 4-Chloro-5-trifluoromethyl-2,2,4-trifluoro-1,3-dioxolane (1) was synthesised by reaction of CF2(OF)(2) with CF3-CH=CFCl; the elimination of HCl from (1) in basic conditions led to the formation of dioxole perfluoro-4-methyl-1,3-dioxole (2). Both these synthetic steps gave the corresponding product in high yield.A new synthetic route for the preparation of CF3-CH=CFCl, starting from CF2ClBr and CH2=CF2, together with some examples of polymerisation products obtained by reaction of dioxole (2) with fluoroolefins are also reported. (C) 2003 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.jfluchem.2003.10.009

文献信息

• Free Radical Additions Involving Fluorine Compounds. III. The Addition of Bromochlorodifluoromethane to Olefins^1,2
  作者：Paul Tarrant、Alan M. Lovelace

  DOI：10.1021/ja01608a076

  日期：1955.2.1
• Perfluoro-4-methyl-1,3-dioxole: a new monomer for high-Tg amorphous fluoropolymers
  作者：Antonio Russo、Walter Navarrini

  DOI：10.1016/j.jfluchem.2003.10.009

  日期：2004.1

  A 4-Chloro-5-trifluoromethyl-2,2,4-trifluoro-1,3-dioxolane (1) was synthesised by reaction of CF2(OF)(2) with CF3-CH=CFCl; the elimination of HCl from (1) in basic conditions led to the formation of dioxole perfluoro-4-methyl-1,3-dioxole (2). Both these synthetic steps gave the corresponding product in high yield.A new synthetic route for the preparation of CF3-CH=CFCl, starting from CF2ClBr and CH2=CF2, together with some examples of polymerisation products obtained by reaction of dioxole (2) with fluoroolefins are also reported. (C) 2003 Elsevier B.V. All rights reserved.