5,5,7,7-Tetramethyl-6-oxa-5,7-disilahexacyclo[9.6.6.02,10.04,8.012,17.018,23]tricosa-2,4(8),9,12,14,16,18,20,22-nonaene | 1254084-31-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 蒽
• 英文名称: 5,5,7,7-Tetramethyl-6-oxa-5,7-disilahexacyclo[9.6.6.02,10.04,8.012,17.018,23]tricosa-2,4(8),9,12,14,16,18,20,22-nonaene
• CAS: 1254084-31-5
• 化学式: C₂₄H₂₄OSi₂
• 分子量: 384.625
• InChiKey: NINMSGQIZAJLLJ-UHFFFAOYSA-N

物化性质

• 熔点：
  264-266 °C
• 沸点：
  426.4±34.0 °C(predicted)
• 密度：
  1.17±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.53
• 重原子数：
  27
• 可旋转键数：
  0
• 环数：
  7.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  1-吡咯甲酸叔丁酯 、 5,5,7,7-Tetramethyl-6-oxa-5,7-disilahexacyclo[9.6.6.02,10.04,8.012,17.018,23]tricosa-2,4(8),9,12,14,16,18,20,22-nonaene 在 三氟甲磺酸 、 碘苯二乙酸 、 potassium fluoride 、 四丁基氟化铵 作用下， 以 二氯甲烷 、 四氢呋喃 为溶剂， 以55%的产率得到Tert-butyl 25-azaheptacyclo[10.6.6.15,8.02,11.04,9.013,18.019,24]pentacosa-2(11),3,6,9,13,15,17,19,21,23-decaene-25-carboxylate
  参考文献：
  名称：

  Oxadisilole Fused Triptycene and Extended Triptycene: Precursors of Triptycyne and Extended Triptycyne

  摘要：

  With benzobisoxadisilole 1 as a 1,4-benzdiyne equivalent, oxadisilole fused triptycene Sand extended triptycene 6 were synthesized. Triptycenes 5 and 6 are new precursors of triptycyne 7 and extended triptycyne 8 respectively via the phenyliodination/fluoride induced elimination protocol. Using these two arynes, a series or triptycene derivatives Were synthesized.

  DOI：

  10.1021/jo1016025
• 作为产物：
  描述：

  1,3,5,7-tetrahydro-1,1,3,3,5,5,7,7-octamethylbenzo[1,2-c:4,5-c']bis[1,2,5]oxadisilole 、 蒽 在 三氟甲磺酸 、 碘苯二乙酸 、 potassium fluoride 、 四丁基氟化铵 作用下， 以 二氯甲烷 、 四氢呋喃 为溶剂， 反应 10.0h， 以82%的产率得到5,5,7,7-Tetramethyl-6-oxa-5,7-disilahexacyclo[9.6.6.02,10.04,8.012,17.018,23]tricosa-2,4(8),9,12,14,16,18,20,22-nonaene
  参考文献：
  名称：

  Oxadisilole Fused Triptycene and Extended Triptycene: Precursors of Triptycyne and Extended Triptycyne

  摘要：

  With benzobisoxadisilole 1 as a 1,4-benzdiyne equivalent, oxadisilole fused triptycene Sand extended triptycene 6 were synthesized. Triptycenes 5 and 6 are new precursors of triptycyne 7 and extended triptycyne 8 respectively via the phenyliodination/fluoride induced elimination protocol. Using these two arynes, a series or triptycene derivatives Were synthesized.

  DOI：

  10.1021/jo1016025

文献信息

• Anthracene Capped Isobenzofuran: A Synthon for the Preparations of Iptycenes and Iptycene Quinones
  作者：Bao-Jian Pei、Wing-Hong Chan、Albert W. M. Lee

  DOI：10.1021/ol200309v

  日期：2011.4.1

  Anthracene capped isobenzofuran 5 (5,6-(9,10-dihydroanthracen-9,10-yl)isobenzofuran) was synthesized for the first time. It is a highly reactive and versatile synthon for the synthesis of iptycene derivatives via Diels−Alder reactions. Cycloadducts 10 could be readily deoxygenated to iptycenes 11. Two new reactions of PhI(OAc)2/TfOH have been explored. Endoxides 10 were directly oxidized to iptycene

  首次合成了蒽封端的异苯并呋喃5（5,6-（9,10-二氢蒽-9,10-基）异苯并呋喃）。它是一种高反应性且用途广泛的合成子，可通过Diels-Alder反应合成iptycene衍生物。Cycloadducts 10可以容易地脱氧到iptycenes 11。已探索了PhI（OAc）2 / TfOH的两个新反应。内氧化物10被直接氧化为并茂苯醌12，而异苯并呋喃5方便地转化为三并苯二醛16。H形中央延伸的戊烯并茂醌13和14 也被合成了。
• Oxadisilole Fused Triptycene and Extended Triptycene: Precursors of Triptycyne and Extended Triptycyne
  作者：Bao-Jian Pei、Wing-Hong Chan、Albert W. M. Lee

  DOI：10.1021/jo1016025

  日期：2010.11.5

  With benzobisoxadisilole 1 as a 1,4-benzdiyne equivalent, oxadisilole fused triptycene Sand extended triptycene 6 were synthesized. Triptycenes 5 and 6 are new precursors of triptycyne 7 and extended triptycyne 8 respectively via the phenyliodination/fluoride induced elimination protocol. Using these two arynes, a series or triptycene derivatives Were synthesized.