1-(2-hydroxypropyl)-5-methylimidazolidin-2-one | 6497-75-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑烷类
• 英文名称: 1-(2-hydroxypropyl)-5-methylimidazolidin-2-one
• CAS: 6497-75-2
• 化学式: C₇H₁₄N₂O₂
• 分子量: 158.2
• InChiKey: GHSSGQJZCZSFFH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.5
• 重原子数：
  11
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  52.6
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  二氧化碳 、 异丙醇胺 180.0 ℃ 、10.0 MPa 条件下， 反应 24.0h， 以37.9%的产率得到5-甲基-1,3-恶唑烷-2-酮
  参考文献：
  名称：

  合成 尿素在不存在的情况下来自胺和CO 2的衍生物催化剂 和 溶剂

  摘要：

  尿素 从 脂肪族伯胺用CO 2在没有任何催化剂， 有机的 溶剂或其他添加剂。为了优化反应条件，研究了温度，压力，胺浓度，反应时间等实验变量。在优化的条件下获得了令人满意的产量，与存在下的可比性相当。催化剂 和 溶剂。对反应机理的初步研究表明，烷基氨基甲酸烷基铵迅速形成了中间体，然后通过分子内脱水形成了最终产物。

  DOI：

  10.1039/c0gc00059k

文献信息

• [EN] PROCESS TO PREPARE PROPYLENE AMINES AND PROPYLENE AMINE DERIVATIVES<br/>[FR] PROCÉDÉ DE PRÉPARATION DE PROPYLÈNE AMINES ET DE DÉRIVÉS DE PROPYLÈNE AMINES
  申请人：AKZO NOBEL CHEMICALS INT BV

  公开号：WO2019030197A1

  公开（公告）日：2019-02-14

  The present invention relates to a process to prepare propylene amines of the formula NH2-(A-NH-)pR, wherein R is a hydrogen atom or an alkyl group, p is at least 1 when R is an alkyl group, and at least 2 when R is a hydrogen atom, or derivatives or precursors thereof wherein one or more units -NH-A-NH-may be present as a cyclic urea unit. (I) or a cyclic unit (ll) or between two units –NH-A-NH-a carbonyl bond is present, each unit –A-can be independently an alkylene unit and at least one unit –A-is a -C3H6- unit, wherein each -C3H6- unit can be linear or branched, by reacting (i) at least one of a hydroxy-functional compound chosen from the alkanolamine-functional compounds, and dihydroxyalkylene compounds, with (ii) an amine-functional compound,in the presence of (iii) a carbon oxide delivering agent, wherein at least one of the alkanolamine-functional compound, the amine-functional compound and/or the carbon oxide delivering agent contains at least one alkylene unit (A) that is a propylene unit

  本发明涉及一种制备丙烯胺的方法，其化学式为NH2-(A-NH-)pR，其中R是氢原子或烷基，当R是烷基时，p至少为1，当R是氢原子时至少为2，或其衍生物或前体，其中一个或多个单位-NH-A-NH-可以作为环状尿素单位存在。其中一个或两个单位之间存在一个羰基键，每个单位-A-可以独立地是一个烷基单位，至少一个单位-A-是一个-C3H6-单位，其中每个-C3H6-单位可以是直链或支链，通过在(i)至少一种从烷基胺基化合物和二羟基烷基化合物中选择的羟基官能化合物之一，与(ii)胺基官能化合物反应，在(iii)碳氧化物传递剂的存在下，其中至少一种烷基胺基化合物、胺基官能化合物和/或碳氧化物传递剂含有至少一个丙烯基(A)单位。
• Unsaturated compounds containing carbamate terminal groups or urea terminal groups
  申请人：——

  公开号：US20040097642A1

  公开（公告）日：2004-05-20

  A compound contains at least one unsaturated free-radically or cationically polymerizable group and at least one carbamate or urea end group.

  一种化合物含有至少一个不饱和自由基或阳离子可聚合基团和至少一个氨基甲酸酯或脲末端基团。
• PROCESS TO PREPARE PROPYLENE AMINES AND PROPYLENE AMINE DERIVATIVES
  申请人：NOURYON CHEMICALS INTERNATIONAL B.V.

  公开号：US20200361910A1

  公开（公告）日：2020-11-19

  A process is provided to prepare propylene amines of the formula NH 2 —(A—NH—) p R, wherein R is a hydrogen atom or an alkyl group, p is at least 1 when R is an alkyl group, and at least 2 when R is a hydrogen atom, or derivatives or precursors thereof wherein one or more units —NH—A—NH— may be present as a cyclic urea unit or a cyclic unit or between two units —NH—A—NH— a carbonyl bond is present, each unit —A— can be independently an alkylene unit and at least one unit —A— is a —C 3 H 6 — unit, wherein each —C 3 H 6 — unit can be linear or branched. The process includes reacting (i) at least one of a hydroxy-functional compound chosen from the alkanolamine-functional compounds, and dihydroxyalkylene compounds, with (ii) an amine-functional compound, in the presence of (iii) a carbon oxide delivering agent, wherein at least one of the alkanolamine-functional compound, the amine-functional compound and/or the carbon oxide delivering agent contains at least one alkylene unit (A) that is a propylene unit
• US6916854B2
  申请人：——

  公开号：US6916854B2

  公开（公告）日：2005-07-12
• Synthesis of urea derivatives from amines and CO2 in the absence of catalyst and solvent
  作者：Chaoyong Wu、Haiyang Cheng、Ruixia Liu、Qiang Wang、Yufen Hao、Yancun Yu、Fengyu Zhao

  DOI：10.1039/c0gc00059k

  日期：——

  Urea derivatives are obtained in mild to good yield from the reactions of primary aliphatic amines with CO2 in the absence of any catalysts, organic solvents or other additives. To optimize reaction conditions, experimental variables including temperature, pressure, the concentration of amine, reaction time etc. were studied. Satisfactory yields were obtained at the optimized conditions that are comparable

  尿素 从 脂肪族伯胺用CO 2在没有任何催化剂， 有机的 溶剂或其他添加剂。为了优化反应条件，研究了温度，压力，胺浓度，反应时间等实验变量。在优化的条件下获得了令人满意的产量，与存在下的可比性相当。催化剂 和 溶剂。对反应机理的初步研究表明，烷基氨基甲酸烷基铵迅速形成了中间体，然后通过分子内脱水形成了最终产物。