4-Guanidinobutylmyristoylamide | 160854-59-1

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 4-Guanidinobutylmyristoylamide
• 英文别名: N-[4-(diaminomethylideneamino)butyl]tetradecanamide
• CAS: 160854-59-1
• 化学式: C₁₉H₄₀N₄O
• 分子量: 340.5
• InChiKey: WWADPIBIXCUBNP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5
• 重原子数：
  24
• 可旋转键数：
  17
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.89
• 拓扑面积：
  93.5
• 氢给体数：
  3
• 氢受体数：
  2

文献信息

• Production process for a guanidine derivative containing an amido group and for a salt thereof
  申请人：Ajinomoto Co., Inc.

  公开号：EP1270552A2

  公开（公告）日：2003-01-02

  A guanidine derivative containing an amido group, represented by is produced by reacting a guanidine derivative containing an amino group represented by with a fatty acid halide or a fatty acid ester.

  一种含有酰胺基的胍衍生物，由含有氨基的胍衍生物与脂肪酸卤化物或脂肪酸酯反应制得。
• Production process of guanidine derivative containing amido group and salt thereof
  申请人：Ajinomoto Co., Inc.

  公开号：US20040092599A1

  公开（公告）日：2004-05-13

  A guanidine derivative containing an amido group, represented by 1 is produced by reacting a guanidine derivative containing an amino group represented by 2 with a fatty acid halide or a fatty acid ester.

  一种含有氨基的胍衍生物，其代表为 1 代表的含有氨基的胍衍生物反应制得。 2 与脂肪酸卤化物或脂肪酸酯反应制得。
• PREPARATION OF LIPID NANOPARTICLES AND METHODS OF ADMINISTRATION THEREOF
  申请人：ModernaTX, Inc.

  公开号：US20210378980A1

  公开（公告）日：2021-12-09

  The present disclosure provides methods of producing lipid nanoparticle (LNP) formulations and the produced LNP formulations thereof. The present disclosure also provides therapeutic and diagnostic uses related to the produced LNP formulations.
• [EN] PREPARATION OF LIPID NANOPARTICLES AND METHODS OF ADMINISTRATION THEREOF<br/>[FR] PRÉPARATION DE NANOPARTICULES LIPIDIQUES ET LEURS MÉTHODES D'ADMINISTRATION
  申请人：MODERNATX INC

  公开号：WO2020061457A1

  公开（公告）日：2020-03-26

  The present disclosure provides methods of producing lipid nanoparticle (LNP) formulations and the produced LNP formulations thereof. The present disclosure also provides therapeutic and diagnostic uses related to the produced LNP formulations.