Furfural-(2,4-dinitro-phenylhydrazon) | 16416-22-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Furfural-(2,4-dinitro-phenylhydrazon)
• 英文别名: (E)-1-(2,4-dinitrophenyl)-2-(furan-2-ylmethylene)hydrazine；furfural 2,4-dinitrophenylhydrazone；furfural-((E)-2,4-dinitro-phenylhydrazone)；furfural-(2,4-dinitro-phenylhydrazone)；Furfural-((E)-2,4-dinitro-phenylhydrazon)；Furfural-<(E)-2,4-dinitrophenylhydrazon>；N-[(E)-furan-2-ylmethylideneamino]-2,4-dinitroaniline
• CAS: 16416-22-1
• 化学式: C₁₁H₈N₄O₅
• 分子量: 276.208
• InChiKey: JLMSXDMAAIAPCZ-KPKJPENVSA-N

物化性质

• 沸点：
  442.4±45.0 °C(Predicted)
• 密度：
  1.53±0.1 g/cm3(Predicted)
• 溶解度：
  可溶于氯仿（少许）、DMSO（少许）

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  20
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  129
• 氢给体数：
  1
• 氢受体数：
  7

反应信息

• 作为反应物：
  描述：

  乙酸酐 、 Furfural-(2,4-dinitro-phenylhydrazon) 在 吡啶 作用下， 生成 furfural-[acetyl-(2,4-dinitro-phenyl)-hydrazone]
  参考文献：
  名称：

  Bredereck, Chemische Berichte, 1932, vol. 65, p. 1833,1837

  摘要：

  DOI：
• 作为产物：
  描述：

  1-氯-2,4-二硝基苯 在 乙醇 、 硫酸 、 一水合肼 作用下， 生成 Furfural-(2,4-dinitro-phenylhydrazon)
  参考文献：
  名称：

  Purgotti, Gazzetta Chimica Italiana, 1894, vol. 24 I, p. 568

  摘要：

  DOI：

文献信息

• Phase-Transfer Catalyzed Synthesis of 1,2-Disubstituted Aziridines from Sulfuranes and Schiff Bases or Aldehyde Arylhydrazones
  作者：Ram S. Tewari、Alok K. Awasthi、Anita Awasthi

  DOI：10.1055/s-1983-30330

  日期：——
• Darzens synthesis of 2,2-dichloro-3-(2-furyl)-3-hydroxypropionic acid derivatives
  作者：V. A. Mamedov、V. N. Valeeva、L. A. Antokhina、A. V. Chernova、R. R. Shagidullin、G. M. Doroshkina、I. A. Nuretdinov

  DOI：10.1007/bf00703696

  日期：1994.8

  Esters and amides of 2,2-dichloro-3-(2-furyl)-3-hydroxypropionic acid were prepared by the reaction of furfural with dichloroacetic acid derivatives under the conditions of the Darzens condensation. The structures of the reaction products were confirmed by their H-1 NMR and IR spectra and chemical transformations.
• SYNTHESIS AND ANTIFUNGAL ACTIVITY OF DIARYL HYDRAZONES FROM 2,4-DINITROPHENYLHYDRAZINE
  作者：SERGIO ORTIZ、RONALD NELSON、VÍCTOR KESTERNICH、MARCIA PÉREZ-FEHRMANN、PHILIPPE CHRISTEN、LAURENCE MARCOURT

  DOI：10.4067/s0717-97072016000300015

  日期：——

  A new series of diarylhydrazones derived from 2,4-dinitrophenylhydrazine were synthesized via condensation with aromatic aldehydes whose structures have been determined by mass spectrometry, infrared spectroscopy, and nuclear magnetic resonance spectra. Yields were 50-99%. All compounds were screened in vitro for their antifungal activity. Preliminary results indicated that compounds 3g and 3h exhibited promising antifungal potency. Understanding of the structure of these compounds establishes a preliminary structure-activity relationship to form the basis of further investigation.
• Spectrophotometric Studies of Some 2,4-Dinitrophenylhydrazones
  作者：L. A. Jones、J. C. Holmes、R. B. Seligman

  DOI：10.1021/ac60110a013

  日期：1956.2.1
• Formation, Separation, and Identification of 2,4-Dinitrophenylhydrazones
  作者：L. I. Braddock、K. Y. Garlow、L. I. Grim、A. F. Kirkpatrick、S. W. Pease、A. J. Pollard、E. F. Price、T. L. Reissmann、H. A. Rose、M. L. Willard

  DOI：10.1021/ac60074a025

  日期：1953.2.17