Cu-GHK

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: Cu-GHK
• 英文别名: 6-amino-2-[[2-[(2-aminoacetyl)amino]-3-(1H-imidazol-5-yl)propanoyl]amino]hexanoic acid;copper
• 化学式: C14H24CuN6O4
• 分子量: 403.92
• InChiKey: DIWZQABMLHSNJR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.91
• 重原子数：
  25
• 可旋转键数：
  11
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.57
• 拓扑面积：
  176
• 氢给体数：
  6
• 氢受体数：
  7

文献信息

• Compositions and methods for treatment of psoriasis
  申请人：Patt M. Leonard

  公开号：US20050197282A1

  公开（公告）日：2005-09-08

  A method for treating psoriasis of the skin of a patient employs topically applying to the affected skin a composition comprising at least one peptide copper complex. In other embodiments, the present invention is directed to such a method where the composition used therefor further comprises certain disclosed active agents, including active drug and active cosmetic substances. In a related aspect, further embodiments of the present invention are directed to compositions comprising at least one peptide copper complex and certain active drug and active cosmetic substances that render the compositions particularly effective in treating psoriasis.

  一种治疗患者皮肤银屑病的方法，是将一种包含至少一种肽铜复合物的组合物局部涂抹在患处皮肤上。在其他实施方案中，本发明涉及这样一种方法，其中使用的组合物进一步包含某些已公开的活性剂，包括活性药物和活性化妆品物质。在一个相关方面，本发明的进一步实施方案涉及包含至少一种肽铜复合物和某些活性药物和活性化妆品物质的组合物，这些组合物使其在治疗牛皮癣方面特别有效。
• Encapsulated peptide copper complexes and compositions and methods related thereto
  申请人：Patt M. Leonard

  公开号：US20050260275A1

  公开（公告）日：2005-11-24

  This invention relates to compositions comprising encapsulated peptide copper complexes, and, additionally, to such compositions formulated for use as pharmaceutical and cosmetic products, as well as to medical devices that comprise such compositions.

  本发明涉及包含封装肽铜复合物的组合物，此外，还涉及配制成药物和化妆品使用的此类组合物，以及包含此类组合物的医疗器械。
• Polyethylene glycol - peptide copper complexes and compositions and methods related thereto
  申请人：Patt M. Leonard

  公开号：US20060052287A1

  公开（公告）日：2006-03-09

  This invention relates to compositions comprising polyethylene glycol molecules coupled to peptide copper complexes, and, additionally, to such compositions formulated for use as pharmaceutical and cosmetic products, as well as to medical devices that comprise such compositions.

  本发明涉及由聚乙二醇分子与多肽铜络合物偶联而成的组合物，还涉及配制成药物和化妆品的此类组合物，以及包含此类组合物的医疗器械。
• PRESERVED AND STABLE COMPOSITIONS CONTAINING PEPTIDE COPPER COMPLEXES AND METHODS RELATED THERETO
  申请人：PROCYTE CORPORATION

  公开号：EP1613302B1

  公开（公告）日：2009-12-23
• COMPOSITIONS AND METHODS FOR TREATMENT OF ROSACEA
  申请人：PROCYTE CORPORATION

  公开号：EP1633385A1

  公开（公告）日：2006-03-15