hydrazinecarboxamide of 5-nitro-indol-2,3-dione | 777889-78-8

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: hydrazinecarboxamide of 5-nitro-indol-2,3-dione
• 英文别名: 5-nitro-3-(indolin-2-one)hydrazinecarboxamide；5-nitro-3-[indolin-2-one] of carboxamide；[(5-nitro-2-oxoindol-3-yl)amino]urea
• CAS: 777889-78-8；223591-23-9
• 化学式: C₉H₇N₅O₄
• 分子量: 249.186
• InChiKey: INKFKBAXXXYVGI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.12
• 重原子数：
  18.0
• 可旋转键数：
  2.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  143.21
• 氢给体数：
  3.0
• 氢受体数：
  5.0

反应信息

• 作为反应物：
  描述：

  hydrazinecarboxamide of 5-nitro-indol-2,3-dione 、 manganese(II) chloride tetrahydrate 以 甲醇 为溶剂， 生成 [Mn(hydrazinecarboxamide of 5-nitro-indol-2,3-dione-H)2]
  参考文献：
  名称：

  Garg, Rekha; Saini, Mahesh Kumar; Fahmi, Nighat, Indian Journal of Chemistry, Section A: Inorganic, Physical, Theoretical and Analytical, 2005, vol. 44, # 12, p. 2433 - 2438

  摘要：

  DOI：
• 作为产物：
  描述：

  2-羟基亚氨基-N-(4-硝基苯基)-乙酰胺 在 硫酸 作用下， 以 乙醇 、 水 为溶剂， 反应 0.17h， 生成 hydrazinecarboxamide of 5-nitro-indol-2,3-dione
  参考文献：
  名称：

  Garg, Rekha; Saini, Mahesh Kumar; Fahmi, Nighat, Indian Journal of Chemistry, Section A: Inorganic, Physical, Theoretical and Analytical, 2005, vol. 44, # 12, p. 2433 - 2438

  摘要：

  DOI：

文献信息

• Synthesis and evaluation of isatin derivatives as corrosion inhibitors for Q235A steel in highly concentrated HCl
  作者：Gang Chen、Hui-jun Su、Ying-pan Song、Yu Gao、Jie Zhang、Xiao-jiang Hao、Jing-rui Zhao

  DOI：10.1007/s11164-012-0870-9

  日期：2013.10

  A series of inhibitors—isatin derivatives aimed at anticorrosion of Q235A steel—was synthesized. The molecule structures were analyzed by NMR and MS. The inhibition on the corrosion in a concentrated HCl solution as high as 3 M was studied by weight loss, molecular simulation, and potentiodynamic polarization. The results indicate that isatin derivatives act as mixed type (cathodic/anodic) inhibitors. Several compounds were investigated in the formulations, during which compound 6 shows 95.5 % inhibition efficiency under the concentration of 100 mg/L accompanied by urotropine and 1,4-dihydroxy-2-butyne.

  一系列抑制剂——旨在防止Q235A钢腐蚀的靛红衍生物——被合成出来，并通过NMR和MS分析了分子结构。通过失重法、分子模拟和动电位极化法研究了这些衍生物在高达3M浓盐酸溶液中的抑制腐蚀作用。结果表明，靛红衍生物具有混合型（阴极/阳极）抑制剂的作用。在配方中研究了几种化合物，其中化合物6在100mg/L浓度下与乌洛托品和1,4-二羟基-2-丁炔共同作用时表现出95.5%的抑制效率。
• Synthetic, spectral, and antimicrobial aspects of biologically relevant coordination compounds of dioxomolybdenum(VI) and oxovanadium(V)
  作者：R. Garg、N. Fahmi、R. V. Singh

  DOI：10.1134/s1070328408030093

  日期：2008.3

  Heterocyclic ketimines, 5-nitro-3-(indolin-2-one)hydrazinecarbothioamide (L1H), 5-nitro-3-(indolin-2-one)hydrazinecarboxamide (L2H), 6-nitro-3-(indolin-2-one)hydrazinecarbo-thioamide (L3H), and 6-nitro-3-(indolin-2-one) hydrazinecarboxamide (L4H), were prepared by the condensation of thiosemicarbazide and semicarbazide hydrochloride (in the presence of sodium acetate) in ethanol with the respective ketones. The dioxomolybdenum(VI) complexes and oxovanadium(V) complexes have been prepared by mixing dioxobis(2,4-pentanedinato)molybdenum(VI) in 1: 2 molar ratios and vanadium oxytrichloride in 1: 1 and 1: 2 molar ratios with monobasic bidentate ketimines. The resulting complexes have been characterized by elemental analysis, conductance measurements, and spectral studies, including IR, 1H NMR, and UV spectra. The ketimines and their corresponding metal complexes have been tested on a number of pathogenic bacteria and fungi in order to assess their growth inhibition potency at different concentrations.

  杂环酮亚胺、5-硝基-3-(吲哚啉-2-酮)肼基硫代甲酰胺(L1H)、5-硝基-3-(吲哚啉-2-酮)肼基甲酰胺(L2H)、6-硝基-3-(吲哚啉-2-酮)肼基硫代甲酰胺(L3H)、和 6-硝基-3-（吲哚啉-2-酮）肼甲酰胺（L4H）是由硫代氨基脲和盐酸氨基脲（在乙酸钠存在下）在乙醇中与相应的酮缩合制备的。二氧二钼(VI)络合物和氧钒(V)络合物是通过将摩尔比为 1:2 的二氧双(2,4-戊二酸)钼(VI)和摩尔比为 1:1 和 1:2 的氧三氯化钒与单碱基双齿酮亚胺混合而制备的。通过元素分析、电导测量和光谱研究（包括红外光谱、1H NMR 光谱和紫外光谱），对所得复合物进行了表征。这些酮亚胺及其相应的金属复合物已在一些病原细菌和真菌上进行了测试，以评估它们在不同浓度下的生长抑制效力。
• Coordination chemistry of palladium(II) and platinum(II) complexes with bioactive Schiff bases: Synthetic, spectral, and biocidal aspects
  作者：K. Sharma、M. K. Biyala、M. Swami、N. Fahmi、R. V. Singh

  DOI：10.1134/s1070328409020092

  日期：2009.2

  The Schiff bases, 5-nitro-indol-2,3-dionehydrazinecarboxamide (HSCZ1) and 7-nitro-indol-2,3- dionehydrazinecarboxamide (HSCZ2), have been synthesized by the condensation of 5-nitro-indol-2,3-dione and 7-nitro-1H-indol-2,3-dione with semicarbazide hydrochloride, respectively. The palladium(II) and platinum( II) complexes have been prepared by mixing palladium chloride and platinum chloride in 1: 2 molar

  通过5-硝基-吲哚-2的缩合反应合成了席夫碱5-硝基-吲哚-2，3-二酮肼甲酰胺（HSCZ 1）和7-硝基-吲哚-2，3-二酮肼甲酰胺（HSCZ 2）。 ，3-二酮和7-硝基-1H-吲哚-2,3-二酮分别与盐酸氨基脲一起使用。钯（Ⅱ）和铂（Ⅱ）配合物是通过将氯化钯和氯化铂以1：2摩尔比与一元二齿Schiff碱混合而制得的。钯和铂的配体和配合物已通过元素分析，熔点测定，电导率测定，分子量测定和IR进行了表征11 H NMR和UV光谱研究。这些研究表明，配体以二元二齿模式与金属原子配位，通过氧和氮供体系统配位。因此，已经提出了围绕金属原子的四配位环境。筛选了配体及其配合物对几种病原性真菌和细菌的生物活性，发现它们具有明显的杀真菌和杀菌特性。配体之一及其配合物的植物生长调节活性也已在革兰氏植物上记录，并已讨论了结果。