but-2-enedioic acid;ethenoxyethene

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: but-2-enedioic acid;ethenoxyethene
• 化学式: C8H10O5
• 分子量: 186.16
• InChiKey: BPMMHGIISLRQDW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.889
• 重原子数：
  13
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  83.8
• 氢给体数：
  2
• 氢受体数：
  5

文献信息

• Oxypurine nucleosides and their congeners, and acyl derivatives thereof, for improvement of hematopoiesis
  申请人：Pro-Neuron, Inc.

  公开号：US20040235782A1

  公开（公告）日：2004-11-25

  The invention relates to certain oxypurine nucleosides, congeners of such oxypurine nucleosides, and acyl derivatives thereof, and compositions which contain at least one of these compounds. The invention also relates to methods of treating or preventing hematopoietic disorders and modifying hematopoiesis, and treating or preventing inflammatory diseases and bacterial infections by administering a compound or composition of the present invention to an animal.

  本发明涉及某些氧杂嘌呤核苷、这些氧杂嘌呤核苷的同系物和酰基衍生物，以及至少含有这些化合物之一的组合物。本发明还涉及通过向动物施用本发明的化合物或组合物来治疗或预防造血障碍和调节造血以及治疗或预防炎症性疾病和细菌感染的方法。
• Silver halide photographic material
  申请人：KONICA CORPORATION

  公开号：EP0089230A1

  公开（公告）日：1983-09-21

  A silver halide photographic material comprising a support and one or more layers, at least one layer containing a compound of the following formula (1) and at least one compound selected from among the compounds of the following formulae (II), (III) and (IV) is disclosed: Formula (I) (wherein A and B each represent non-metallic atoms necessary to form a hereto ring; and X is a negative ion) Formul (II) Wherein R, is a hydrogen atom, a hydroxyl group, the same or different halogen atoms, an alkyl group which may have a substituent, an aralkyl group which may have a substituent, an alkoxy group which may have a substituent, an acyl group which may have a substituent, a carboxymethyl group which may have a substituent, -COOM or -SO3M group, (wherein M is a hydrogen atom, an alkali metal atom or an ammonium group); R2 is a -COOM or S03M group, (wherein M is as defined above); and n is an integer of 1, 2, or 3.) Formula (III) (wherein R3 has the same meaning as R2 defined above; and n2 is the same as n1 defined above) Formula (IV) (wherein R4 has the same meaning as R2 defined above; and n3 and n4 each is an integer of 0 or 1 but they are not both 0, and n5 is an integer of 1 or 2.

  本发明公开了一种卤化银感光材料，它包括一个支撑体和一层或多层，其中至少一层含有下式（1）的化合物和至少一种选自下式（II）、（III）和（IV）的化合物：式 (I) (其中 A 和 B 分别代表形成本征环所必需的非金属原子；X 为负离子） 式（II） 其中 R 是氢原子、羟基、相同或不同的卤素原子、可能具有取代基的烷基、可能具有取代基的芳烷基、可能具有取代基的烷氧基、可能具有取代基的酰基、可能具有取代基的羧甲基、-COOM 或-SO3M 基团（其中 M 是氢原子、碱金属原子或铵基团）；R2 是-COOM 或 S03M 基团（其中 M 如上定义）；以及 n 是 1、2 或 3 的整数。)式（III） (其中 R3 与上文定义的 R2 意义相同；n2 与上文定义的 n1 意义相同） 式（IV） (其中 R4 与上文定义的 R2 意义相同；n3 和 n4 各为 0 或 1 的整数，但不同时为 0，且 n5 为 1 或 2 的整数。
• Sustained-release preparation of basic medical agent hydrochloride
  申请人：SUMITOMO PHARMACEUTICALS COMPANY, LIMITED

  公开号：EP0425298A2

  公开（公告）日：1991-05-02

  A preparation obtained by coating granules containing both a basic medical agent hydrochloride (e.g. arotinolol hydrochloride) and a polyanion the particles of which are present in the form of a discontinuous layer, with a film containing a slightly water-soluble substance, can release the agent at a controlled rate independently of physiological conditions in the gastrointestinal tract of a patient to whom the preparation has been administered orally.

  一种制剂是通过在含有盐酸基本医用制剂（如盐酸阿罗替洛尔）和聚阴离子（其颗粒以不连续层的形式存在）的颗粒上包覆一层含有微水溶性物质的薄膜而获得的，这种制剂可以不受口服制剂的患者胃肠道生理条件的影响，以可控的速度释放制剂。
• Lubricious coatings containing polymers with vinyl and carboxylic aced moieties
  申请人：UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION

  公开号：EP0747071A1

  公开（公告）日：1996-12-11

  Lubricious coatings comprising a binder polymer having a vinyl moiety and a carboxylic acid moiety and a hydrophilic polymer are disclosed. The coatings can be applied to a variety of substrates such as, for example, catheters, stents, dilatation balloons, guide wires, endotracheal tubes, instruments, implants and other biomedical devices and can provide exceptional lubricity and abrasion resistance. Processes for applying the lubricious coatings in either one or two coating steps are also disclosed.

  本发明公开了由具有乙烯基和羧酸基的粘合剂聚合物以及亲水性聚合物组成的润滑涂层。 这种涂层可用于各种基质，例如导管、支架、扩张球囊、导丝、气管导管、器械、植入物和其他生物医学设备，并可提供优异的润滑性和耐磨性。 此外，还公开了通过一个或两个涂敷步骤涂敷润滑涂层的工艺。
• Stabilizers for vinyl ether-based coating systems
  申请人：AlliedSignal Inc.

  公开号：EP0909797A1

  公开（公告）日：1999-04-21

  This invention relates to vinyl ether-based coatings for which properties such as color stability, thermal stability, mechanical stability, hydrolytic stability, and resistance to embrittlement may be maintained and properties hydrogen generation and blocking are minimized. The coatings comprise a vinyl ether-containing composition polymerizable by actinic, gamma ray, or electron beam radiation comprising; (a) an oligomer or a mixture of oligomers which are monofunctional, multifunctional, or a mixture of both monofunctional and multifunctional and which have a reactive functionality chosen from the group consisting of epoxy, acrylate, vinyl ether, maleate, or mixtures thereof, (b) monomers which are monofunctional, multifunctional or a mixture of both monofunctional and multifunctional monomers and which have a reactive functionality chosen from the group consisting of epoxy, acrylate, vinyl ether, maleate, or mixtures thereof, wherein at least one of (a) or (b) must contain a vinyl ether functionality; (c) a photoinitiator, optionally including a sensitizer, chosen from the group consisting of a cationic photoinitiator and a radical photoinitiator; and (d) a thermal oxidation stabilizer. The composition also comprises additives including as hydrogen stabilizers: mixtures of hindered phenols, organic sulfides or disulfides, and transition metal salts of organic compounds. Adhesion to a substrate, particularly glass, is achieved by coupling agents including vinyl ether urethane siloxane compounds.

  本发明涉及以乙烯基醚为基础的涂料，可保持其颜色稳定性、热稳定性、机械稳定性、水解稳定性和抗脆性等特性，并可最大限度地减少氢的生成和阻塞。这种涂料包括一种可通过放 射线、伽马射线或电子束辐射聚合的含乙烯基醚组合物，该组合物包括(a) 低聚物或低聚物混合物，它们是单官能团、多官能团或单官能团和多官能团的混合物，具有选自环氧树脂、丙烯酸酯、乙烯基醚、马来酸盐或其混合物的反应官能团； (b) 单官能团、多官能团或单官能团和多官能团的混合物、(b) 单官能度、多官能度或单官能度和多官能度单体的混合物，其活性官能度可从环 氧、丙烯酸酯、乙烯基醚、马来酸酯或其混合物组成的组中选择，其中 (a) 或 (b) 中至少有一种必须含有乙烯基醚官能度；(c) 光引发剂，可选包括敏化剂，选自由阳离子光引发剂和自由基光引发剂组成 的组；以及 (d) 热氧化稳定剂。该组合物还包括作为氢稳定剂的添加剂：受阻酚、有机硫化物或二硫化物的混合物，以及有机化合物的过渡金属盐。通过偶联剂（包括乙烯基醚聚氨酯硅氧烷化合物）可实现与基材（尤其是玻璃）的粘合。