S-[2-[3-[[4-[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-2-hydroxy-3,3-dimethylbutanoyl]amino]propanoylamino]ethyl] 3-hydroxy-3-(4-hydroxy-3-methoxyphenyl)propanethioate

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: S-[2-[3-[[4-[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-2-hydroxy-3,3-dimethylbutanoyl]amino]propanoylamino]ethyl] 3-hydroxy-3-(4-hydroxy-3-methoxyphenyl)propanethioate
• 化学式: C₃₁H₄₆N₇O₂₀P₃S
• 分子量: 961.7
• InChiKey: SDNPOBCYTJKZSD-HRCMCYLASA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -5.2
• 重原子数：
  62
• 可旋转键数：
  24
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.55
• 拓扑面积：
  439
• 氢给体数：
  11
• 氢受体数：
  25

文献信息

• Genetic engineering of Pseudomonas putida KT2440 for rapid and high yield production of vanillin from ferulic acid
  申请人：BASF SE

  公开号：US10036044B2

  公开（公告）日：2018-07-31

  The present invention relates to an improved biocatalytic process for producing vanillin from ferulic acid based on a genetically engineered Pseudomonas strains, as well as to said Pseudemonas strains.

  本发明涉及一种基于基因工程假单胞菌菌株以及所述假单胞菌菌株从阿魏酸生产香兰素的改良生物催化工艺。
• Bacterial strains for the production of vanillin
  申请人：LESAFFRE ET COMPAGNIE

  公开号：US10450591B2

  公开（公告）日：2019-10-22

  The invention relates to an Amycolatopsis strain derived from the Amycolatopsis Zyl 926 strain having at least one additional copy of the FCS and ECH genes encoding feruloyl-CoA-synthetase and enoyl-CoA-hydratase/aldolase integrated at the integration site of the φC31 phage. The invention also relates to the method for producing such strains, the integration cassette of the FCS and ECH genes, the use of said strains in a method for producing vanillin, and a method for producing vanillin.

  本发明涉及一种来源于Amycolatopsis Zyl 926菌株的Amycolatopsis菌株，该菌株在φC31噬菌体的整合位点上整合了至少一个额外拷贝的编码阿魏酰-CoA-合成酶和烯酰-CoA-水解酶/醛醇酶的FCS和ECH基因。本发明还涉及生产这种菌株的方法、FCS 和 ECH 基因的整合盒、在生产香兰素的方法中使用所述菌株以及生产香兰素的方法。
• Process for converting ferulic acid into vanillin
  申请人：Symrise AG

  公开号：EP3000888B1

  公开（公告）日：2018-12-05
• GENETIC ENGINEERING OF PSEUDOMONAS PUTIDA KT2440 FOR RAPID AND HIGH YIELD PRODUCTION OF VANILLIN FROM FERULIC ACID
  申请人：BASF SE

  公开号：EP3024939B1

  公开（公告）日：2018-11-28
• NOVEL BACTERIAL STRAINS FOR THE PRODUCTION OF VANILLIN
  申请人：LESAFFRE ET COMPAGNIE

  公开号：US20180320204A1

  公开（公告）日：2018-11-08

  The invention relates to an Amycolatopsis strain derived from the Amycolatopsis Zyl 926 strain having at least one additional copy of the FCS and ECH genes encoding feruloyl-CoA-synthetase and enoyl-CoA-hydratase/aldolase integrated at the integration site of the φC31 phage. The invention also relates to the method for producing such strains, the integration cassette of the FCS and ECH genes, the use of said strains in a method for producing vanillin, and a method for producing vanillin.