hexadecanoic acid;octadec-9-enoic acid

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: hexadecanoic acid;octadec-9-enoic acid
• 化学式: C34H66O4
• 分子量: 538.9
• InChiKey: IPVSQRLZENDNRL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  12.206
• 重原子数：
  38
• 可旋转键数：
  29
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.88
• 拓扑面积：
  74.6
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• [EN] FATTY ACID SYNTHASE INHIBITORS<br/>[FR] INHIBITEURS DE L'ACIDE GRAS SYNTHASE
  申请人：UNIV DUKE

  公开号：WO2017184844A1

  公开（公告）日：2017-10-26

  The present disclosure relates to a method for inhibiting Fatty Acid. Synthase (FASN) with, a FASN inhibitor, methods for treating cancer and viral infections with a FASN inhibitor, and compounds and compositions inhibiting FASN,

  本公开涉及一种使用FASN抑制剂抑制脂肪酸合酶（FAtty Acid Synthase，FASN）的方法，使用FASN抑制剂治疗癌症和病毒感染的方法，以及抑制FASN的化合物和组合物。
• Use of polyamine compounds in prevention of mastitis
  申请人：Merck & Co., Inc.

  公开号：EP0032031A2

  公开（公告）日：1981-07-15

  1-amino-3-[1,5-di-(4-isopropylphenyl)-pent-3-ylamino]-propan-2-ol and its salts are used as an udder wash and teat dip for mastitis prevention in lactating cows. Compositions for such use are disclosed. The compounds and compositions are of low toxicity.

  1-氨基-3-[1,5-二(4-异丙基苯基)-戊-3-基氨基]-2-丙醇及其盐类可用作乳房清洗剂和乳头浸剂，用于预防哺乳母牛乳腺炎。公开了用于这种用途的组合物。这些化合物和组合物毒性低。
• ORAL APPLIZIERBARE PHARMAZEUTISCHE DARREICHUNGSFORM MIT MODIFIZIERTER FREISETZUNG
  申请人：Bayer Aktiengesellschaft

  公开号：EP3826619A1

  公开（公告）日：2021-06-02
• Relationship of a specific metabolite to insulin resistance
  申请人：Newgard B. Christopher

  公开号：US20070110716A1

  公开（公告）日：2007-05-17

  Provided are methods and reagents for reducing ketone levels (for example, β-hydroxybutyrate) in skeletal muscle. Also provided are methods and reagents for treating insulin resistant states, such as diabetes. Further provided are screening methods for identifying compounds to reduce skeletal muscle ketone levels and/or to treat insulin resistance, for example, insulin resistance associated with diabetes.
• Antibody Selective for a Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand Receptor and Uses Thereof
  申请人：Zhou Tong

  公开号：US20070298039A1

  公开（公告）日：2007-12-27

  An antibody of the invention interacts with human DR5 to produce agonistic or antagonistic effects downstream of o the receptor including inhibition of cell proliferation and apoptosis. Nucleic acid sequences and amino acid sequences of anti-DR5 antibodies have been elucidated and vectors and cells containing and expressing these sequences have been generated. Methods and uses for the antibodies are detailed including treatment of apoptosis-related disease and treatment of dysregulated cell growth.