1,2,3-tris-(4-hydroxy-benzoyloxy)-propane | 133081-95-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1,2,3-tris-(4-hydroxy-benzoyloxy)-propane
• 英文别名: 1,2,3-Tris-(4-hydroxy-benzoyloxy)-propan；2,3-Bis[(4-hydroxybenzoyl)oxy]propyl 4-hydroxybenzoate
• CAS: 133081-95-5
• 化学式: C₂₄H₂₀O₉
• 分子量: 452.417
• InChiKey: LCPVXFCFVFOPSE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.9
• 重原子数：
  33
• 可旋转键数：
  11
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  140
• 氢给体数：
  3
• 氢受体数：
  9

反应信息

• 作为产物：
  描述：

  2,3-Bis[(4-phenylmethoxybenzoyl)oxy]propyl 4-phenylmethoxybenzoate 在 palladium 10% on activated carbon 、 氢气 作用下， 以 四氢呋喃 、 甲醇 为溶剂， 反应 15.0h， 生成 1,2,3-tris-(4-hydroxy-benzoyloxy)-propane
  参考文献：
  名称：

  多酚类化合物及其制备方法和应用

  摘要：

  本发明涉及多酚类化合物及其制备方法和应用。所述多酚类化合物具有如以下通式I所示的结构，并且所述多酚类化合物具有抗病毒，特别是抗流感病毒和冠状病毒活性。

  公开号：

  CN114685574A

文献信息

• A case controlled study of laparoscopic incisional hernia repair
  作者：R. Chari、V. Chari、M. Eisenstat、R. Chung

  DOI：10.1007/s004649900079

  日期：2000.2

  Background: Although the feasibility of laparoscopic incisional herniorrhaphy has been demonstrated, its advantages over the open technique are still unproven,Methods: Fourteen consecutive laparoscopic incisional hernia repairs were compared with 14 matched controls of the open repair done by the same surgeon at the same institution. The controls were selected by a medical record technician not connected with the study, The cases were selected to match diagnoses, ASA status, and body weight as closely as possible. The outcome data for operating time, blood loss, hospitalization, resumption of oral intake, and postoperative complications were analyzed for statistically significant differences.Results: There was no statistical difference between the two groups in the parameters of blood loss, hospital days, or days to oral intake, The laparoscopic operation took 40% longer. Similar complications were seen in both groups. No mortality or early recurrences occurred in either group.Conclusion: Laparoscopic incisional hernia repair of at least moderate complexity had no demonstrable advantage over the open repair in the present study.
• 多酚类化合物及其制备方法和应用
  申请人：中国科学院上海药物研究所

  公开号：CN114685574A

  公开（公告）日：2022-07-01

  本发明涉及多酚类化合物及其制备方法和应用。所述多酚类化合物具有如以下通式I所示的结构，并且所述多酚类化合物具有抗病毒，特别是抗流感病毒和冠状病毒活性。