Methyl 2-oxo-1-(3-phenylpropanoyl)imidazolidine-4-carboxylate

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: Methyl 2-oxo-1-(3-phenylpropanoyl)imidazolidine-4-carboxylate
• 化学式: C₁₄H₁₆N₂O₄
• 分子量: 276.29
• InChiKey: ZJVZAJZTMLOELN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1
• 重原子数：
  20
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  75.7
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• [EN] DIRHODIUM CATALYST COMPOSITIONS AND METHODS FOR USING SAME<br/>[FR] COMPOSITIONS CATALYTIQUES AU DIRHODIUM ET PROCEDES D'UTILISATION
  申请人：UNIV NEW YORK STATE RES FOUND

  公开号：WO2003018183A2

  公开（公告）日：2003-03-06

  Disclosed is method for increasing the efficiency of a dirhodium catalyst. The method includes providing a dirhodium catalyst, providing an organic ester, and contacting the dirhodium catalyst and the organic ester under conditions effective to increase the efficiency of the dirhodium catalyst. The organic ester is selected such that it is not a substrate for catalysis by the dirhodium catalyst. Dirhodium catalyst compositions which include a dirhodium catalyst and an organic ester are also disclosed. In these compositions, the organic ester is not a substrate for catalysis by the dirhodium catalyst. The method and compositions can be used in a number of reactions, including insertion reactions (e.g., C-H insertions, Si-H insertions, O-H insertions, and N-H insertions) cyclopropanation reactions, annulations (e.g., [3 + 2] annulations and [3 + 4] annulations), and φ, φ-diarylalkanoate syntheses.
• [EN] SOLID SUPPORT DIRHODIUM CATALYST COMPOSITIONS AND METHODS FOR MAKING AND USING SAME<br/>[FR] COMPOSITIONS CATALYTIQUES DE DIRHODIUM A SUPPORT SOLIDE ET PROCEDES DE PRODUCTION ET D'UTILISATION DE CES DERNIERES
  申请人：UNIV NEW YORK STATE RES FOUND

  公开号：WO2003018184A2

  公开（公告）日：2003-03-06

  Disclosed are dirhodium catalyst compositions. One such dirhodium catalyst composition includes a dirhodium catalyst and a solid support. The dirhodium catalyst includes a Rh-Rh moiety and four bridging ligand moieties. The dirhodium catalyst and the solid support are bound together, but they are not covalently bound together via one or more of the bridging ligand moieties. Another such dirhodium catalyst composition includes a dirhodium tetracarboxylate catalyst and a solid support, and the dirhodium tetracarboxylate catalyst and the solid support are bound together. Yet another such dirhodium catalyst composition includes a dirhodium catalyst and a solid support, where the dirhodium catalyst includes a Rh-Rh moiety and where the dirhodium catalyst and the solid support are bound together via at least one of the rhodiums' axial positions. The compositions can be used in a number of reactions, including insertion reactions (e.g., C-H insertions, Si-H insertions, O-H insertions, and N-H insertions), cyclopropanation reactions, annulations (e.g., [3 + 2] annulations and [3 + 4] annulations), and φ,φ-diarylalkanoate synthesis. Methods for making the dirhodium catalyst compositions are also disclosed.
• [EN] 4-SUBSTITUTED AND 7-SUBSTITUTED INDOLES, BENZOFURANS, BENZOTHIOPHENES, BENZIMIDAZOLES, BENZOXAZOLES, AND BENZOTHIAZOLES AND METHODS FOR MAKING SAME<br/>[FR] INDOLES, BENZOFURANES, BENZOTHIOPHENES, BENZIMIDAZOLES, BENZOXAZOLES ET BENZOTHIAZOLES 4-SUBSTITUES ET 7-SUBSTITUES ET PROCEDES DE FABRICATION DE CEUX-CI
  申请人：UNIV NEW YORK STATE RES FOUND

  公开号：WO2006135804A1

  公开（公告）日：2006-12-21

  [EN] Disclosed are 4 -substituted and 7-substituted indoles, benzofurans, benzothiophenes, benzimidazoles, benzoxazoles, and benzothiazoles. Also disclosed are methods for making 4 -substituted and 7-substituted indoles, benzofurans, benzothiophenes, benzimidazoles, benzoxazoles, and benzothiazoles, including those having the formulae. The methods include contacting a 4- substituted-6, 7-dihydro indole, benzofuran, benzothiophene, benzimidazole, benzoxazole, or benzothiazole compound or a 7 -substituted- 4, 5-dihydro indole, benzofuran, benzothiophene, benzimidazole, benzoxazole, or benzothiazole compound with a vinyldiazo compound in the presence of a dirhodium catalyst.
  [FR] L'invention concerne des indoles, benzofuranes, benzothiophènes, benzimidazoles, benzoxazoles et benzothiazoles 4 substitués et 7-substitués. L'invention concerne également des procédés de fabrication des indoles, benzofuranes, benzothiophènes, benzimidazoles, benzoxazoles et benzothiazoles 4 substitués et 7-substitués, notamment ceux des formules selon l'invention. Les procédés consistent à mettre en contact un composé d'indole, benzofurane, benzothiophène, benzimidazole, benzoxazole ou benzothiazole 4- substitués-6, 7-dihydro ou un composé d'indole, benzofurane, benzothiophène, benzimidazole, benzoxazole ou benzothiazole 7 -substitué- 4, 5-dihydro avec un composés de vinyldiazo en présence d'un catalyseur de dirhodium.