Proline, N-methyl-, butyl ester

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: Proline, N-methyl-, butyl ester
• 英文别名: butyl 1-methylpyrrolidine-2-carboxylate
• 化学式: C₁₀H₁₉NO₂
• 分子量: 185.26
• InChiKey: TXARCVDUIMCSNN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  13
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.9
• 拓扑面积：
  29.5
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• [EN] DI-ESTER DERIVATIVES AS SHORT ACTING NEUROMUSCULAR BLOCKERS<br/>[FR] DERIVES DE DIESTER UTILISES EN TANT QUE BLOQUEURS NEUROMUSCULAIRES A ACTION BREVE
  申请人：THERASCI LTD

  公开号：WO2003070243A1

  公开（公告）日：2003-08-28

  The invention relates to substituted di-ester compounds joined by an alkylene linker group, in which each ester group independently is substituted by a nitrogen containing group in which the nitrogen is quaternised or is part of a guanidine group and derivatives, to pharmaceutical compositions, and to their use as medicaments as neuromuscular blocking agents. Preferred pharmaceutical compositions are those which are suitable for parenteral administration by intravenous or intramuscular or subcutaneous injection.