Pentadecyl pentanoate

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: Pentadecyl pentanoate
• 化学式: C₂₀H₄₀O₂
• 分子量: 312.5
• InChiKey: ZDYLNFIQQYOUMX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.6
• 重原子数：
  22
• 可旋转键数：
  18
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.95
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• MODULATION OF THE IMMUNE RESPONSE
  申请人：Nguyen David-Huy Nhu

  公开号：US20120009222A1

  公开（公告）日：2012-01-12

  The present invention provides lipidoids that can be used to modulate the immune response in a subject. Lipidoids are prepared by the conjugate addition of an amine to an acrylate to acrylamide. The lipidoids form complexes or particles with an immunostimulatory polynucleotide, which are then administerd to a subject. Such compositions have been found to stimulate the production of cytokines and increase both humoral and cell-mediate immune response. The invention also provides pharmaceuti-cal compositions thereof and methods for using the same.
• [EN] THERAPEUTIC COMPOSITIONS<br/>[FR] COMPOSITIONS THÉRAPEUTIQUES
  申请人：SHIRE HUMAN GENETIC THERAPIES

  公开号：WO2009097332A2

  公开（公告）日：2009-08-06

  Therapeutic compositions containing therapeutic agents and nitrogen-containing lipids are described. These tertiary amine-containing polymers are preferably biodegradable and biocompatible. Nanoparticles, microparticles, and complexes containing lipid/therapeutic agent complexes are also described.