N-Propyl-9-octadecenamide

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: N-Propyl-9-octadecenamide
• 英文别名: N-propyloctadec-9-enamide
• 化学式: C₂₁H₄₁NO
• 分子量: 323.6
• InChiKey: OGWMUXVWUHUNMI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.9
• 重原子数：
  23
• 可旋转键数：
  17
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  29.1
• 氢给体数：
  1
• 氢受体数：
  1

文献信息

• [EN] ANTIMICROBIAL CONJUGATES, METHOD FOR PRODUCTION AND USES THEREOF<br/>[FR] CONJUGUÉS ANTIMICROBIENS, PROCÉDÉ DE PRODUCTION ET UTILISATIONS DE CEUX-CI
  申请人：SEC DEP FOR HEALTH

  公开号：WO2015136311A1

  公开（公告）日：2015-09-17

  The present disclosure relates to polyamine conjugates, its isomers, prodrugs and pharmaceutically acceptable salts thereof. The present disclosure also relates to process of preparation of polyamine conjugates, its stereoisomers, prodrugs, pharmaceutically acceptable salts thereof,and to pharmaceutical compositions containing them. The compounds of the present disclosure are useful in the treatment, prevention or suppression of diseases mediated by microbes.

  本公开涉及聚胺共轭物、其异构体、前药和其药用盐。本公开还涉及聚胺共轭物、其立体异构体、前药、其药用盐的制备方法，以及含有它们的药物组合物。本公开的化合物在治疗、预防或抑制由微生物介导的疾病方面具有用途。
• A METHOD OF TREATING PERIPHERAL INFLAMMATORY DISEASE
  申请人：Dublin City University

  公开号：EP3095444A1

  公开（公告）日：2016-11-23

  An active for use in the treatment or inhibition of an inflammatory disease associated with over-activation of Toll-like Receptor 4 (TLR4), Toll-like Receptor 2 (TLR2) and Myeloid differentiating protein 88 (Myd88) adaptor-like protein (Mal) while maintaining a subject's ability to respond normally to a pathogen, in which the active is an oleamide or a derivative thereof.

  一种用于治疗或抑制与Toll样受体4（TLR4）、Toll样受体2（TLR2）和髓样分化蛋白88（Myd88）适配样蛋白（Mal）过度激活相关的炎症性疾病，并同时保持受试者对病原体正常反应能力的活性物质为油酰胺或其衍生物。
• [EN] ORGANOSILICON COMPOUNDS AND COMPOSITIONS<br/>[FR] COMPOSÉS ET COMPOSITIONS D'ORGANOSILICIUM
  申请人：DITECPESA S A

  公开号：WO2019020770A1

  公开（公告）日：2019-01-31

  The present invention relates to organosilicon compounds of formula (I) as well as to compositions, bitumens and asphalt compositions comprising said organosilicon compounds, and to the use of said asphalt compositions in construction.

  本发明涉及具有式(I)的有机硅化合物，以及包括所述有机硅化合物的组合物、沥青和沥青组合物，以及所述沥青组合物在建筑中的使用。
• RUBBER COMPOSITION AND PNEUMATIC TIRE
  申请人：BRIDGESTONE CORPORATION

  公开号：EP1083199A1

  公开（公告）日：2001-03-14

  There are provided a rubber composition having a high modulus of elasticity and a good workability, and a pneumatic tire. A rubber composition comprising at least one of natural rubber and synthetic diene rubbers as a rubber ingredient, at least one maleimide compound, and at least one nitrogen-containing compound selected from the group consisting of polyaniline, hydrazide, and amine compound is used in a tread.

  提供了一种具有高弹性模量和良好加工性能的橡胶组合物以及一种充气轮胎。 一种橡胶组合物包含天然橡胶和合成二烯橡胶中的至少一种橡胶成分、至少一种马来酰亚胺化合物和至少一种从聚苯胺、酰肼和胺化合物组成的组中选出的含氮化合物，用于胎面。
• Polymaleimide-containing rubber composition and tire
  申请人：BRIDGESTONE CORPORATION

  公开号：EP1199331A1

  公开（公告）日：2002-04-24

  A rubber composition comprises at least one rubber ingredient selected from natural rubber and synthetic rubbers, and a polymaleimide synthesized by reacting at least one of anhydrous maleic acid and anhydrous citraconic acid with methylene polyaniline.

  一种橡胶组合物包含至少一种橡胶成分，选自天然橡胶和合成橡胶，以及一种聚马来酰亚胺，由无水马来酸和无水柠檬酸中的至少一种与亚甲基聚苯胺反应合成。