N-Acetyl-3-(propyldisulfanyl)alanine

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: N-Acetyl-3-(propyldisulfanyl)alanine
• 英文别名: 2-acetamido-3-(propyldisulfanyl)propanoic acid
• 化学式: C₈H₁₅NO₃S₂
• 分子量: 237.3
• InChiKey: IOXRPLPFAGFDFU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.7
• 重原子数：
  14
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  117
• 氢给体数：
  2
• 氢受体数：
  5

文献信息

• Organosulfur compounds for the prevention and treatment of neurodegenerative diseases
  申请人：Ott David M.

  公开号：US20130143967A1

  公开（公告）日：2013-06-06

  S-allylmercapto-N-acetylcysteine and related compounds are disclosed which can be administered in order to provide protection from the formation of aldehyde-protein adducts, protein carbonylation, protein aggregation, and the resulting neuroinflammation. Various neurodegenerative diseases which are suitable for treatment using these compounds include Alzheimer's disease, senile dementia, Parkinson's disease, multiple sclerosis, Lewy body disease, peripheral neuropathy, spinal cord injury, stroke and cerebral ischemia.
• Organosulfur Compounds for the Prevention and Treatment of Neurodegenerative Diseases
  申请人：Ott David Michael

  公开号：US20130165515A1

  公开（公告）日：2013-06-27

  Divalent salts of S-allylmercapto-N-acetylcysteine and related compositions are disclosed which can be administered in order to provide protection from the formation of aldehyde-protein adducts, protein carbonylation, protein aggregation, and the resulting neuroinflammation. Various neurodegenerative diseases which are suitable for treatment using these compositions include Alzheimer's disease, senile dementia, Parkinson's disease, multiple sclerosis, Lewy body disease, peripheral neuropathy, spinal cord injury, stroke and cerebral ischemia.
• Personal care and medicinal products incorporating bound organosulfur groups
  申请人：Ott David Michael

  公开号：US20140050677A1

  公开（公告）日：2014-02-20

  Personal care products useful for the maintenance of personal appearance and good health and minor treatments that do not require professional health care, as well as products that provide a combination of anti-oxidant, anti-inflammatory, antimicrobial, and anti-aging properties and are suitable for use without a prescription. The products utilize biomembrane permeable organosulfur compounds that can redox cycle between thiol, disulfide, and thiosulfinate forms in response to antioxidants and oxidants that are inside and outside of cells. Example products include an antioxidant skin lotion with anti-inflammatory, antimicrobial, anti-arsenicosis, anti-aging, and deodorant properties.
• ORGANOSULFUR COMPOUNDS FOR THE PREVENTION AND TREATMENT OF NEURODEGENERATIVE DISEASES
  申请人：Ott David Michael

  公开号：US20170100349A1

  公开（公告）日：2017-04-13

  Divalent salts of S-allylmercapto-N-acetylcysteine and related compositions are disclosed which can be administered in order to provide protection from the formation of aldehyde-protein adducts, protein carbonylation, protein aggregation, and the resulting neuroinflammation. Various neurodegenerative diseases which are suitable for treatment using these compositions include Alzheimer's disease, senile dementia, Parkinson's disease, multiple sclerosis, Lewy body disease, peripheral neuropathy, spinal cord injury, stroke and cerebral ischemia.
• US9456999B2
  申请人：——

  公开号：US9456999B2

  公开（公告）日：2016-10-04