3,5-dibenzylidene-1,2,3,5,6,7-hexahydro-8-phenyldicyclopentapyridine | 65758-63-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 3,5-dibenzylidene-1,2,3,5,6,7-hexahydro-8-phenyldicyclopentapyridine
• 英文别名: (4E,12E)-4,12-Dibenzylidene-8-phenyl-2-azatricyclo[7.3.0.03,7]dodeca-1,3(7),8-triene
• CAS: 65758-63-6
• 化学式: C₃₁H₂₅N
• 分子量: 411.546
• InChiKey: YPPVZSOXITUTQJ-XAESMMJOSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.9
• 重原子数：
  32
• 可旋转键数：
  3
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.13
• 拓扑面积：
  12.9
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  3,5-dibenzylidene-1,2,3,5,6,7-hexahydro-8-phenyldicyclopentapyridine 以 乙醇 为溶剂， 生成 (4E,12Z)-4,12-dibenzylidene-8-phenyl-2-azatricyclo[7.3.0.03,7]dodeca-1,3(7),8-triene
  参考文献：
  名称：

  2，6-二苯乙烯基吡啶的结构刚性类似物的蛋白水解性质。通过光化学E→Z异构化和引入能够进行蛋白水解相互作用的取代基来拓宽pH敏感度范围

  摘要：

  系列前瞻性荧光比例宽范围pH指示剂中的蛋白水解相互作用-2,6-二苯乙烯基吡啶的结构刚性类似物-（3E，5E）-3,5-二亚苄基-8-苯基-1,2,3,5,6研究了7,6-六氢二环戊基[b，e]吡啶。与未取代的杂环和2，6-二苯乙烯基吡啶相比，这些化合物中的吡啶氮原子碱性显着较低。研究了光化学E→Z光异构化和侧苯环取代基对酸碱平衡的影响。阐明了多取代化合物酸碱相互作用的复杂多阶段机理。最显着的光谱效应是所研究系列的N，N-二烷基氨基取代的化合物所特有的。

  DOI：

  10.2478/s11532-010-0051-x
• 作为产物：
  描述：

  苯甲醛 、 环戊酮 在 ammonium acetate 作用下， 以 乙醇 为溶剂， 反应 1.0h， 以15%的产率得到3,5-dibenzylidene-1,2,3,5,6,7-hexahydro-8-phenyldicyclopentapyridine
  参考文献：
  名称：

  磷酸二酯的双（烷基胍）受体：抗衡离子、溶剂混合物和腔弹性对络合的影响

  摘要：

  已经合成了四种双（胍）受体，其中胍基团在空间上由八氢吖啶（meso-3 和 d,l-3）或六氢二环戊二烯 [b,e] 吡啶（meso-4 和 d,l-4）预先组织间隔以补充磷酸二酯。这些结构旨在模拟葡萄球菌核酸酶的活性位点，从而与结合的磷酸二酯形成四个氢键，而宿主结构几乎没有重组。合成包括两部分：间隔基的构建和通过胺和硫脲盐之间的分子内环化形成氨基咪唑啉基团

  DOI：

  10.1021/ja00075a021

文献信息

• Photosensitive resin composition, photosensitive element, method for producing substrate with resist pattern, and method for producing printed wiring board
  申请人：HITACHI CHEMICAL COMPANY, LTD.

  公开号：US10564543B2

  公开（公告）日：2020-02-18

  A photosensitive resin composition includes (A) a binder polymer having a structural unit derived from a hydroxyalkyl (meth)acrylate ester having a hydroxyalkyl group having from 1 to 12 carbon atoms, and a structural unit derived from a (meth)acrylic acid; (B) a photopolymerizable compound having an ethylenically unsaturated bond group; (C) a photopolymerization initiator; and (D) a styryl pyridine represented by the Formula (1). In Formula (1), each of R1, R2 and R3 independently represents an alkyl group having from 1 to 20 carbon atoms, an alkoxy group having from 1 to 6 carbon atoms, an alkyl ester group having from 1 to 6 carbon atoms, an amino group, an alkyl amino group having from 1 to 20 carbon atoms, a carboxy group, a ciano group, a nitro group, an acetyl group or a (meth)acryloyl group, each of a, b and c independently represents an integer of from 0 to 5. In a case in which each of a, b and c is independently 2 or more, the plural R1s, R2s, and R3s independently may be the same or different.

  一种光敏树脂组合物包括：(A)一种粘合剂聚合物，其结构单元来源于具有 1 至 12 个碳原子的羟基烷基的羟基烷基（甲基）丙烯酸酯和来源于（甲基）丙烯酸的结构单元；(B)一种具有乙烯不饱和键基的可光聚合化合物；(C)一种光聚合引发剂；以及(D)一种由式(1)表示的苯乙烯基吡啶。在式(1)中，R1、R2 和 R3 各自独立地代表具有 1 至 20 个碳原子的烷基、具有 1 至 6 个碳原子的烷氧基、具有 1 至 6 个碳原子的烷基酯基、氨基、具有 1 至 20 个碳原子的烷基氨基、羧基、腈基、硝基、乙酰基或(甲基)丙烯酰基，a、b 和 c 各自独立地代表 0 至 5 的整数。在 a、b 和 c 中的每一个独立地为 2 或更多的情况下，复数 R1s、R2s 和 R3s 可以独立地相同或不同。
• Composition capillaire comprenant au moins un colorant fluorescent et au moins un agent alcalin hydroxyde, et procédé de mise en forme, de coloration et/ou d'éclaircissement simultanés.
  申请人：L'Oréal

  公开号：EP2018848B1

  公开（公告）日：2013-01-09
• PHOTOSENSITIVE RESIN COMPOSITION, PHOTOSENSITIVE ELEMENT, METHOD FOR PRODUCING SUBSTRATE WITH RESIST PATTERN, AND METHOD FOR PRODUCING PRINTED WIRING BOARD
  申请人：HITACHI CHEMICAL COMPANY, LTD.

  公开号：US20170261851A1

  公开（公告）日：2017-09-14

  A photosensitive res in composition includes (A) a binder polymer having a structural unit derived from a hydroxyalkyl (meth)acrylate ester having a hydroxyalkyl group having from 1 to 12 carbon atoms, and a structural unit derived from a (meth)acrylic acid; (B) a photopolymerizable compound having an ethylenically unsaturated bond group; (C) a photopolymerization initiator; and (D) a styryl pyridine represented by the Formula (1). In Formula (1), each of R 1 , R 2 and R 3 independently represents an alkyl group having from 1 to 20 carbon atoms, an alkoxy group having from 1 to 6 carbon atoms, an alkyl ester group having from 1 to 6 carbon atoms, an amino group, an alkyl amino group having from 1 to 20 carbon atoms, a carboxy group, a ciano group, a nitro group, an acetyl group or a (meth)acryloyl group, each of a, b and c independently represents an integer of from 0 to 5. In a case in which each of a, b and c is independently 2 or more, the plural R 1 s, R 2 s, and R 3 s independently may be the same or different.
• Bis(alkylguanidinium) receptors for phosphodiesters: effect of counterions, solvent mixtures, and cavity flexibility on complexation
  作者：Diane M. Kneeland、Katsuhiko Ariga、Vincent M. Lynch、Chia Yu Huang、Eric V. Anslyn

  DOI：10.1021/ja00075a021

  日期：1993.11

  Four bis(guanidinium) receptors have been synthesized in which the guanidinium groups are spatially preorganized by an octahydroacridine (meso-3 and d,l-3) or hexahydrodicyclopenta[b,e]pyridine (meso-4 and d,l-4) spacer to complement a phosphodiester. These structures are designed to mimic the active site of staphylococcal nuclease and, thereby, form four hydrogen bonds to a bound phosphodiester with

  已经合成了四种双（胍）受体，其中胍基团在空间上由八氢吖啶（meso-3 和 d,l-3）或六氢二环戊二烯 [b,e] 吡啶（meso-4 和 d,l-4）预先组织间隔以补充磷酸二酯。这些结构旨在模拟葡萄球菌核酸酶的活性位点，从而与结合的磷酸二酯形成四个氢键，而宿主结构几乎没有重组。合成包括两部分：间隔基的构建和通过胺和硫脲盐之间的分子内环化形成氨基咪唑啉基团
• Protolytic properties of the structurally rigid analogs of 2,6-distyrylpyridine. Widening the pH sensitivity range by the photochemical E→Z isomerisation and introduction of substituents capable to protolytic interactions
  作者：Oleksiy Grygorovych、Oleksiy Nevskii、Sofia Moskalenko、Vasyl Pivovarenko、Andrey Doroshenko

  DOI：10.2478/s11532-010-0051-x

  日期：2010.8.1

  5-dibenzylidene-8-phenyl-1,2,3,5,6,7-hexahydrodicyclopentano[b,e]pyridine — were investigated. The pyridine nitrogen atom basicity in these compounds is significantly lower in comparison with that of unsubstituted heterocycle and 2,6-distyrylpyridine. The photochemical E→Z photoisomerization and the side benzene rings substituents influence on the acid-base equilibria were studied. The complex multi-stage mechanism

  系列前瞻性荧光比例宽范围pH指示剂中的蛋白水解相互作用-2,6-二苯乙烯基吡啶的结构刚性类似物-（3E，5E）-3,5-二亚苄基-8-苯基-1,2,3,5,6研究了7,6-六氢二环戊基[b，e]吡啶。与未取代的杂环和2，6-二苯乙烯基吡啶相比，这些化合物中的吡啶氮原子碱性显着较低。研究了光化学E→Z光异构化和侧苯环取代基对酸碱平衡的影响。阐明了多取代化合物酸碱相互作用的复杂多阶段机理。最显着的光谱效应是所研究系列的N，N-二烷基氨基取代的化合物所特有的。