Furan-2-carboxylic acid [5-(4-methoxy-phenyl)-[1,3,4]thiadiazol-2-yl]-amide

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: Furan-2-carboxylic acid [5-(4-methoxy-phenyl)-[1,3,4]thiadiazol-2-yl]-amide
• 英文别名: N-[5-(4-methoxyphenyl)-1,3,4-thiadiazol-2-yl]furan-2-carboxamide
• 化学式: C₁₄H₁₁N₃O₃S
• 分子量: 301.32
• InChiKey: SDGHWFHXBAMOOO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  21
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.07
• 拓扑面积：
  106
• 氢给体数：
  1
• 氢受体数：
  6

文献信息

• NOVEL EFFECTIVE ANTIVIRAL COMPOUNDS AND METHODS USING SAME
  申请人：THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA

  公开号：US20170114060A1

  公开（公告）日：2017-04-27

  The present invention includes compounds that are useful in preventing or treating viral infections caused by an enveloped RNA virus, such as viral infections caused by a Filovirus, arenavirus, rhabdovirus, paramyxovirus, orthomyxovirus and/or retrovirus. The present invention further includes compositions comprising such compounds, and methods of treating a viral infection in a subject using such compounds.
• [EN] NOVEL EFFECTIVE ANTIVIRAL COMPOUNDS AND METHODS USING SAME<br/>[FR] NOUVEAUX COMPOSÉS ANTIVIRAUX EFFICACES ET LEURS MÉTHODES D'UTILISATION
  申请人：UNIV PENNSYLVANIA

  公开号：WO2015187827A1

  公开（公告）日：2015-12-10

  The present invention includes compounds that are useful in preventing or treating viral infections caused by an enveloped RNA virus, such as viral infections caused by a filovirus, arenavirus, rhabdovirus, paramyxovirus, orthomyxovirus and/or retrovirus. The present invention further includes compositions comprising such compounds, and methods of treating a viral infection in a subject using such compounds.