3-(4-Cinnamylpiperazino)-N~1~-phenylpropanamide

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 3-(4-Cinnamylpiperazino)-N~1~-phenylpropanamide
• 英文别名: N-phenyl-3-[4-[(E)-3-phenylprop-2-enyl]piperazin-1-yl]propanamide
• 化学式: C₂₂H₂₇N₃O
• 分子量: 349.5
• InChiKey: ZDXSNDXZLWQXLG-JXMROGBWSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  26
• 可旋转键数：
  7
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.32
• 拓扑面积：
  35.6
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• NEUROACTIVE COMPOUNDS AND METHODS OF USING THE SAME
  申请人：THE GENERAL HOSPITAL CORPORATION

  公开号：US20170247383A1

  公开（公告）日：2017-08-31

  The invention described herein relates generally to neuroactive compounds and compositions for the treatment psychotic disorders, methods for treating psychosis using these neuroactive compounds, and methods for screening for novel neuroactive compounds. Certain aspects are directed to a family of compounds called “finazines.” Certain aspects are directed to in vivo screening methods using high-through-put behavioral assays in zebrafish.