2-[2-(Dimethylamino)ethenyl]-1-(4-methylphenyl)-3-nitroindol-6-ol

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯
• 英文名称: 2-[2-(Dimethylamino)ethenyl]-1-(4-methylphenyl)-3-nitroindol-6-ol
• 化学式: C19H19N3O3
• 分子量: 337.4
• InChiKey: GWJHMQLHNMFLKV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  25
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.16
• 拓扑面积：
  74.2
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• SERUM-FREE EXPANSION OF CELLS IN CULTURE
  申请人：Choongwae Pharma Corporation

  公开号：EP1960777B1

  公开（公告）日：2009-10-21
• Serum-free expansion of cells in culture
  申请人：Kahn Michael

  公开号：US20070128669A1

  公开（公告）日：2007-06-07

  Methods and agents are disclosed for modulating the interaction of β-catenin or γ-catenin with CBP or p300. Agents that increase the binding of CBP to β-catenin are associated with enhancing the β-catenin-related proliferation of adult stem cells, including hematopoietic stem cells, neural stem cells, skin stem cells, and pancreatic stem cells, as well as embryonic stem cells.