2-[(E)-3-(furan-2-yl)prop-2-enoyl]indene-1,3-dione

• 分子结构分类: 有机化合物 - 苯类化合物 - 茚满类
• 英文名称: 2-[(E)-3-(furan-2-yl)prop-2-enoyl]indene-1,3-dione
• 化学式: C₁₆H₁₀O₄
• 分子量: 266.25
• InChiKey: KDHIKSJDTLPCPE-BQYQJAHWSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  20
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.06
• 拓扑面积：
  64.4
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• Treating and/or preventing insulin-resistance related weight gain
  申请人：University of South Florida

  公开号：US10688063B2

  公开（公告）日：2020-06-23

  Provided herein are methods of preventing or reducing weight gain in a subject in need thereof by administering 2-acetylcyclopentane-1,3-dione (ACPD).

  本文提供了通过施用 2-乙酰基环戊烷-1,3-二酮（ACPD）来防止或减少有需要的受试者体重增加的方法。
• TREATING AN ATYPICAL PROTEIN KINASE C ENZYME ABNORMALITY
  申请人：UNIVERSITY OF SOUTH FLORIDA

  公开号：US20160175274A1

  公开（公告）日：2016-06-23

  Provided herein are compounds, compositions, pharmaceutical formulations, methods of treating and methods of using aPKC inhibitors for treating and/or preventing of aPKC abnormalities.
• TREATING AND/OR PREVENTING INSULIN-RESISTANCE RELATED WEIGHT GAIN
  申请人：Farese Robert Vito

  公开号：US20180028488A1

  公开（公告）日：2018-02-01

  Provided herein are methods of preventing or reducing weight gain in a subject in need thereof by administering 2-acetylcyclopentane-1,3-dione (ACPD).
• US9795584B2
  申请人：——

  公开号：US9795584B2

  公开（公告）日：2017-10-24
• [EN] TREATING AN ATYPICAL PROTEIN KINASE C ENZYME ABNORMALITY<br/>[FR] TRAITEMENT D'UNE ANOMALIE DE L'ENZYME PROTÉINE KINASE C ATYPIQUE
  申请人：UNIV SOUTH FLORIDA A FLORIDA NON PROFIT CORP

  公开号：WO2015017549A1

  公开（公告）日：2015-02-05

  Provided herein are compounds, compositions, pharmaceutical formulations, methods of treating and methods of using aPKC inhibitors for treating and/or preventing of aPKC abnormalities.