6-(3,4-dimethylphenyl)-1,4,5,7-tetramethyl-6H-pyrrolo[3,4-d]pyridazine

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯
• 英文名称: 6-(3,4-dimethylphenyl)-1,4,5,7-tetramethyl-6H-pyrrolo[3,4-d]pyridazine
• 英文别名: 6-(3,4-dimethylphenyl)-1,4,5,7-tetramethylpyrrolo[3,4-d]pyridazine
• 化学式: C₁₈H₂₁N₃
• 分子量: 279.4
• InChiKey: JVDMFNQDRKCPDC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  21
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  30.7
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• Antifungal agents and uses thereof
  申请人：University of Massachusetts

  公开号：US10350217B2

  公开（公告）日：2019-07-16

  Antimicrobial agents, compositions that include the agent(s) and use(s) thereof are provided. Also disclosed are screening assays for identifying antimicrobial agents.

  提供了抗菌剂、包括抗菌剂的组合物及其用途。还公开了用于鉴定抗菌剂的筛选测定法。
• ANTIFUNGAL AGENTS AND USES THEREOF
  申请人：University of Massachusetts

  公开号：US20140142107A1

  公开（公告）日：2014-05-22

  Antimicrobial agents, compositions that include the agent(s) and use(s) thereof are provided. Also disclosed are screening assays for identifying antimicrobial agents.
• US7465730B2
  申请人：——

  公开号：US7465730B2

  公开（公告）日：2008-12-16
• US9648880B2
  申请人：——

  公开号：US9648880B2

  公开（公告）日：2017-05-16
• [EN] TREATMENT OF NEUROPATHIC PAIN WITH 6H-PYRROLO[3,4-D]PYRIDAZINE COMPOUNDS<br/>[FR] TRAITEMENT DE LA DOULEUR NEUROPATHIQUE AU MOYEN DE COMPOSES 6H-PYRROLO[3,4-D]PYRIDAZINE
  申请人：MERCK & CO INC

  公开号：WO2004006836A2

  公开（公告）日：2004-01-22

  6H-pyrrolo[3,4-d]pyridazine compounds and methods of their use of as ligands of voltage gated calcium channels (VGCC), useful in the treatment of neuropathic pain, and psychiatric and mood disorders such as, for example, schizophrenia, anxiety, depression, panic, and bipolar disorder, as well as in the treatment of pain, Parkinson s disease, cognitive dysfunction, epilepsy, circadian rhythm disorders, drug addiction, drug abuse, drug withdrawal and other