methyl 5-methyl-4-oxohexanoate | 77342-49-5

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: methyl 5-methyl-4-oxohexanoate
• 英文别名: 1-Hydroxy-6-methyl-2,5-heptandion；1-Hydroxy-6-methylheptane-2,5-dione
• CAS: 77342-49-5
• 化学式: C₈H₁₄O₃
• 分子量: 158.197
• InChiKey: ATHTWJQVHGWXFP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.1
• 重原子数：
  11
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  54.4
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  5-methyl-4-(6-phenanthridinylmethoxy)hexanal 在 溴 、 碳酸氢钠 作用下， 以 水 、 乙腈 为溶剂， 反应 0.25h， 生成 methyl 5-methyl-4-oxohexanoate
  参考文献：
  名称：

  Photolytic generation of ketones from 6-phenanthridinylmethyl ethers of secondary alcohols

  摘要：

  Ketones are generated by photolysis (> 320 nm) of 6-phenanthridinylmethyl ethers of secondary alcohols. The 6-phenanthridinylmethyl group may therefore be utilized as a latent carbonyl function, especially as the 6-phenanthridinyl-methyl group is chemically inert toward hydroboration, Grignard additions, LiAlH4-reduction, bromination or ozonolysis at other parts of the molecule.

  DOI：

  10.1016/s0040-4020(01)88353-8

文献信息

• Stetter, Hermann; Mohrmann, Karl-Heinrich; Schlenker, Walter, Chemische Berichte, 1981, vol. 114, # 2, p. 581 - 596
  作者：Stetter, Hermann、Mohrmann, Karl-Heinrich、Schlenker, Walter

  DOI：——

  日期：——
• STETTER H.; MOHRMANN K.-H.; SCHLENKER W., CHEM. BER., 1981, 114, NO 2, 581-596
  作者：STETTER H.、 MOHRMANN K.-H.、 SCHLENKER W.

  DOI：——

  日期：——
• Photolytic generation of ketones from 6-phenanthridinylmethyl ethers of secondary alcohols
  作者：Vatcharin Rukachaisirikul、Reinhard W. Hoffmann

  DOI：10.1016/s0040-4020(01)88353-8

  日期：1992.11

  Ketones are generated by photolysis (> 320 nm) of 6-phenanthridinylmethyl ethers of secondary alcohols. The 6-phenanthridinylmethyl group may therefore be utilized as a latent carbonyl function, especially as the 6-phenanthridinyl-methyl group is chemically inert toward hydroboration, Grignard additions, LiAlH4-reduction, bromination or ozonolysis at other parts of the molecule.