5-Amino-1-tert-butylimidazole-4-carboxamide

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 5-Amino-1-tert-butylimidazole-4-carboxamide
• 化学式: C₈H₁₄N₄O
• 分子量: 182.22
• InChiKey: YAAJLHMJFQQKSE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.3
• 重原子数：
  13
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  86.9
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• NUCLEOSIDE DERIVATIVES FOR TREATMENT OF CALICIVIRIDAE INFECTIONS, INCLUDING NOROVIRUS INFECTIONS
  申请人：Schinazi Raymond F.

  公开号：US20090280084A1

  公开（公告）日：2009-11-12

  A method and composition for treating a host infected with a Caliciviridae virus, such as a Norovirus, comprising administering an effective treatment amount of a described modified nucleoside or a pharmaceutically acceptable salt thereof, is provided.
• DC-SIGN ANTIBODY CONJUGATES COMPRISING STING AGONISTS
  申请人：NOVARTIS AG

  公开号：US20210170043A1

  公开（公告）日：2021-06-10

  Provided herein are immunoconjugates comprising an anti-DC-SIGN antibody conjugated to a STING agonist. Also disclosed are methods of making the immunoconjugates and methods of treating cancer using the immunoconjugates.
• US8415321B2
  申请人：——

  公开号：US8415321B2

  公开（公告）日：2013-04-09