1-Acetoxy-2,3-diphenylpyrrolo[1,2-b]pyridazine | 135613-53-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯
• 英文名称: 1-Acetoxy-2,3-diphenylpyrrolo[1,2-b]pyridazine
• 英文别名: (6,7-Diphenylpyrrolo[1,2-b]pyridazin-5-yl) acetate
• CAS: 135613-53-5
• 化学式: C₂₁H₁₆N₂O₂
• 分子量: 328.37
• InChiKey: IQWJITMJTXMVPQ-UHFFFAOYSA-N

物化性质

• 密度：
  1.19±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  25
• 可旋转键数：
  4
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.05
• 拓扑面积：
  43.6
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  二苯基环丙烯酮 在 吡啶 作用下， 以 1,4-二氧六环 、 甲醇 为溶剂， 反应 1.0h， 生成 1-Acetoxy-2,3-diphenylpyrrolo[1,2-b]pyridazine
  参考文献：
  名称：

  Indolizines. 5. Preparation and structural assignments of azaindolizinols

  摘要：

  Diphenylcyclopropenone reacts smoothly with a variety of aromatic N-heterocycles to provide aza- and benzazaindolizinols. Although known in the literature, these compounds had been assigned incorrect structures. The preparation and physical properties of a number of derivatives, along with unequivocal assignments of structure based on a variety of NMR techniques, is described herein.

  DOI：

  10.1021/jo00019a024

文献信息

• Indolizines. 5. Preparation and structural assignments of azaindolizinols
  作者：Charles H. Weidner、Frank M. Michaels、Douglas J. Beltman、Cheryl J. Montgomery、Donald H. Wadsworth、Brian T. Briggs、Matthew L. Picone

  DOI：10.1021/jo00019a024

  日期：1991.9

  Diphenylcyclopropenone reacts smoothly with a variety of aromatic N-heterocycles to provide aza- and benzazaindolizinols. Although known in the literature, these compounds had been assigned incorrect structures. The preparation and physical properties of a number of derivatives, along with unequivocal assignments of structure based on a variety of NMR techniques, is described herein.