7,8-bis(benzyloxy)-6-methoxy-2-phenylhexahydropyrano[3,2-b]pyran-4-one | 1400906-94-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 7,8-bis(benzyloxy)-6-methoxy-2-phenylhexahydropyrano[3,2-b]pyran-4-one
• 英文别名: (2S,3R,4S,4aS,6S,8aS)-2-methoxy-6-phenyl-3,4-bis(phenylmethoxy)-3,4,4a,6,7,8a-hexahydro-2H-pyrano[3,2-b]pyran-8-one
• CAS: 1400906-94-6
• 化学式: C₂₉H₃₀O₆
• 分子量: 474.554
• InChiKey: YRMDVCHKHFZIQN-SLXMPOKMSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  35
• 可旋转键数：
  8
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.34
• 拓扑面积：
  63.2
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  1-methyl-2,3,4-tri-O-benzyl-7-deoxy-7-diazo-α-D-glucoheptopyran-6-ulose 在 tetrakis(trifluoroacetato)rhodium(II) 作用下， 以 二氯甲烷 为溶剂， 反应 0.25h， 生成 7,8-bis(benzyloxy)-6-methoxy-2-phenylhexahydropyrano[3,2-b]pyran-4-one 、 7,8-bis(benzyloxy)-6-methoxy-2-phenylhexahydropyrano[3,2-b]pyran-4-one
  参考文献：
  名称：

  Study on Metal-Induced Reactions of α-Diazocarbonyl Glucosides

  摘要：

  Conversions of diazocarbonyl carbohydrate compounds catalyzed by a series of rhodium and copper catalysts in conventional heating or microwave conditions were investigated. C-H insertion product was obtained in the presence of Rh-2(OAc)(4). Intermolecular reactions rather than intramolecular reactions occurred in the presence of copper catalysts.

  DOI：

  10.1021/jo300986c

文献信息

• Study on Metal-Induced Reactions of α-Diazocarbonyl Glucosides
  作者：Zhu Guan、Li-He Zhang、Pierre Sinaÿ、Yongmin Zhang

  DOI：10.1021/jo300986c

  日期：2012.10.19

  Conversions of diazocarbonyl carbohydrate compounds catalyzed by a series of rhodium and copper catalysts in conventional heating or microwave conditions were investigated. C-H insertion product was obtained in the presence of Rh-2(OAc)(4). Intermolecular reactions rather than intramolecular reactions occurred in the presence of copper catalysts.