Pyretrin II | 121-29-9

• 物质功能分类: 化学农药原药 - 杀虫剂 - 拟除虫菊脂杀虫剂
• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: Pyretrin II
• 英文别名: [2-methyl-4-oxo-3-[(2E)-penta-2,4-dienyl]cyclopent-2-en-1-yl] 3-[(E)-3-methoxy-2-methyl-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate
• CAS: 121-29-9
• 化学式: C₂₂H₂₈O₅
• 分子量: 372.5
• InChiKey: VJFUPGQZSXIULQ-VKTMSVCMSA-N

物化性质

• 比旋光度：
  D19 +14.7° (isooctane-ether)
• 沸点：
  bp0.007 192-193°
• 密度：
  1.12±0.1 g/cm3(Predicted)
• 溶解度：
  可溶于氯仿（少许）、DMSO（少许）、甲醇（少许）
• 颜色/状态：
  Viscous liquid
• 蒸汽压力：
  3.98X10-7 mm Hg at 25 °C
• 稳定性/保质期：
  Oxidizes rapidly and becomes inactive in air.
• 旋光度：
  Specific optical rotation: -6 deg at 20 °C/D (diethyl ether, percentage concentration = 5%)
• 分解：
  When heated to decomp it emits acrid smoke and irritating fumes.
• 腐蚀性：
  Non-corrosive
• 折光率：
  Index of refraction: 1.5258 at 20 °C/D
• 保留指数：
  2615;2629

计算性质

• 辛醇/水分配系数(LogP)：
  4.4
• 重原子数：
  27
• 可旋转键数：
  9
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  69.7
• 氢给体数：
  0
• 氢受体数：
  5

安全信息

• 危险等级：
  6.1(b)
• 危险品标志：
  Xn,N
• 安全说明：
  S13,S60,S61
• 危险类别码：
  R20/21/22
• 海关编码：
  29183000
• 危险品运输编号：
  UN 2902
• 包装等级：
  III
• 危险类别：
  6.1(b)

制备方法与用途

根据提供的信息,可以总结除虫菊素的几个关键点:

1. 除虫菊素主要存在于白花除虫菊花中,含量约为0.9-1.3%。

2. 生产方法:

   • 可用石油醚回流萃取、浓缩、脱蜡和脱色等步骤精制得到高纯度产品。
   • 或者使用混合溶剂抽提,如甲醇/煤油、石油醚/乙腈等。

3. 除虫菊素为神经毒剂,见光易分解。应避免阳光直射和高温保存。

4. 毒性:接触皮肤会引起刺痛感;大量摄入可引起全身症状如头痛、恶心等。

5. 主要用途:

   • 生产气雾杀虫剂
   • 制作蚊香
   • 制造动物香波
   • 用于绿色农药

6. 注意事项:

   • 避免与碱性农药混用
   • 施药时应尽量让药剂接触害虫

7. 使用方法:

   • 按照不同害虫类型选择合适的稀释倍数和施药时间
   • 喷洒在傍晚效果更好

8. 急救:无特殊解毒剂,主要对症治疗。

文献信息

• Ectoparasiticidal compositions and methods of their use
  申请人：——

  公开号：US20030040504A1

  公开（公告）日：2003-02-27

  The present invention provides compositions and methods for killing mammalian ectoparasites and eggs. The present invention provides compositions comprising active ingredients, such as, for example, terpenes, such as dipentene and/or D limonene; and/or terpene-ols, such as, for example, terpineol and 1-terpinen-4-ol; and/or 1,2,3,4,-tetrahydronaphthalene; and/or aromatic alcohols; and/or essential oils. The present invention also provides, compositions and methods for killing mammalian ectoparasites and eggs which are resistant to ingredient(s) in established insecticides, such as for example, malathion, permethrin and/or lindane.

  本发明提供了用于杀死哺乳动物寄生虫和卵的组合物和方法。本发明提供了包含活性成分的组合物，例如萜烯，如二戊烯和/或D-柠檬烯；和/或萜烯醇，例如萜烯醇和1-萜烯-4-醇；和/或1,2,3,4-四氢萘；和/或芳香醇；和/或精油。本发明还提供了用于杀死哺乳动物寄生虫和卵的组合物和方法，这些寄生虫和卵对已有杀虫剂成分，例如马拉硫磷、氯菊酯和/或林丹，具有抗药性。
• COMPOSITIONS AND METHODS FOR TREATING SURFACES INFECTED WITH ECTOPARASITIC INSECTS AND/OR PREVENTING RE-INFESTATION BY THE SAME
  申请人：——

  公开号：US20020009476A1

  公开（公告）日：2002-01-24

  Compositions and methods are disclosed for treating a hair-bearing surface of a warm-blooded animal, including humans, dogs and cats infested with an ectoparasitic insect, such as lice and/or fleas. Compositions and methods are also disclosed for preventing the infestation or re-infestation of an ectoparasitic insect, such as lice and/or fleas on a hair-bearing surface of a warm-blooded animal, including humans, dogs and cats. The compositions include either a water-soluble polyalkylene glycol or a water-soluble polyalkylene oxide mixed with a polymer or copolymer comprising polyalkylene oxide having carboxylic acid-containing residues. Methods of the invention include topical application to a hair-bearing surface of an effective amount of a composition of this invention, and maintaining the same on the surface for a sufficient period of time to treat the surface. Further optional steps include washing or rinsing the composition from the surface, as well as combing the hair associated with the treated surface.

  本发明公开了用于治疗温血动物（包括人、狗和猫）受体外寄生昆虫（如虱子和/或跳蚤）侵扰的毛发表面的组合物和方法。本发明还公开了用于防止体外寄生昆虫（如虱子和/或跳蚤）在温血动物（包括人、狗和猫）的毛发表面寄生或再次寄生的组合物和方法。组合物包括水溶性聚亚烷基二醇或水溶性聚环氧烷与聚合物或共聚物混合，聚合物或共聚物包括具有含羧酸残留物的聚环氧烷。本发明的方法包括在毛发表面局部施用有效量的本发明组合物，并在毛发表面保持足够的时间以处理毛发表面。进一步的可选步骤包括清洗或冲洗表面的组合物，以及梳理与处理过的表面相关的头发。
• COMPOSITIONS AND METHODS FOR DELOUSING
  申请人：——

  公开号：US20020022014A1

  公开（公告）日：2002-02-21

  Compositions and methods are disclosed for delousing warm-blooded animals, in need thereof, including humans. The compositions include either a water-soluble polyalkylene glycol or a water-soluble polyalkylene oxide mixed with a polymer or copolymer comprising polyalkylene oxide having carboxylic acid-containing residues. Methods of the invention include topical application to a hair-bearing surface of an effective amount of a composition of this invention, and maintaining the same on the surface for a sufficient period of time to delouse the surface. Further optional steps include washing or rinsing the composition from the surface, as well as combing the hair associated with the treated surface.

  本发明公开了用于给包括人类在内的需要脱毛的温血动物脱毛的组合物和方法。这些组合物包括水溶性聚亚烷基二醇或水溶性聚环氧烷与含有含羧酸残基的聚环氧烷的聚合物或共聚物混合。本发明的方法包括在毛发表面局部施用有效量的本发明组合物，并在毛发表面保持足够的时间使毛发表面脱毛。进一步的可选步骤包括清洗或冲洗表面的组合物，以及梳理与处理过的表面相关的头发。
• [EN] COMPOSITIONS AND METHODS FOR CONTROLLING ECTOPARASITIC INSECTS<br/>[FR] COMPOSITIONS ET PROCEDES UTILISES POUR LA LUTTE CONTRE LES INSECTES ECTOPARASITES
  申请人：BELL, Thomas, A.

  公开号：WO1999029174A1

  公开（公告）日：1999-06-17

  (EN) Compositions and methods are disclosed for treating a hair-bearing surface of a warm-blooded animal, including humans, dogs and cats infested with an ectoparasitic insect, such as lice and/or fleas. Compositions and methods are also disclosed for preventing the infestation or re-infestation of an ectoparasitic insect, such as lice and/or fleas on a hair-bearing surface of a warm-blooded animal, including humans, dogs and cats. The compositions include either a water-soluble polyalkylene glycol or a water-soluble polyalkylene oxide mixed with a polymer or copolymer comprising polyalkylene oxide having carboxylic acid-containing residues. Methods of the invention include topical application to a hair-bearing surface of an effective amount of a composition of this invention, and maintaining the same of the surface for a sufficient period of time to treat the surface. Further optional steps include washing or rinsing the composition from the surface, as well as combing the hair associated with the treated surface.(FR) L'invention concerne des compositions et des procédés pour le traitement d'une surface poilue ou chevelue d'un animal à sang chaud, dont les humains, les chiens et les chats, infestés par un insecte ectoparasite, tel que les poux et/ou les puces. Elle porte aussi sur des compositions et des procédés pour prévenir l'infestation ou la réinfestation par un insecte ectoparasite, tel que les poux et/ou les puces, sur une surface poilue ou chevelue d'un animal à sang chaud, dont les humains, les chiens et les chats. Lesdites compositions comprennent, soit du polyalkylène glycol hydrosoluble, soit un oxyde de polyalkylène hydrosoluble mélangé à un polymère ou à un copolymère comprenant de l'oxyde de polyalkylène comportant des résidus contenant de l'acide carboxylique. Les procédés de l'invention consistent à appliquer localement sur une surface poilue ou chevelue, une dose efficace d'une composition de l'invention, et à maintenir ladite composition sur ladite surface pendant suffisamment de temps pour que la surface soit traitée. Les procédés peuvent éventuellement comprendre des étapes supplémentaires, comme le lavage ou le rinçage, de sorte que la composition soit enlevée de la surface, ainsi que le peignage des poils ou des cheveux associés à la surface traitée.