1,1,13,13-tetraphenyl-4,7,10-trioxa-1,12-tridecadiene | 1224127-32-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1,1,13,13-tetraphenyl-4,7,10-trioxa-1,12-tridecadiene
• 英文别名: [3-[2-[2-(3,3-Diphenylprop-2-enoxy)ethoxy]ethoxy]-1-phenylprop-1-enyl]benzene；[3-[2-[2-(3,3-diphenylprop-2-enoxy)ethoxy]ethoxy]-1-phenylprop-1-enyl]benzene
• CAS: 1224127-32-5
• 化学式: C₃₄H₃₄O₃
• 分子量: 490.642
• InChiKey: LYMVAOFZDFAONQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.8
• 重原子数：
  37
• 可旋转键数：
  14
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.18
• 拓扑面积：
  27.7
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  3,6-dioxaocta-1,8-diyl bis(3-oxobutanoate) 、 1,1,13,13-tetraphenyl-4,7,10-trioxa-1,12-tridecadiene 在 manganese(III) triacetate dihydrate 、 溶剂黄146 作用下， 反应 0.67h， 以33%的产率得到15,31-dimethyl-3,6,9,12,16,20,23,26,30-nonaoxa-2,13-dioxo-17,17,29,29-tetraphenyltricyclo[26.3.0.0(14,18)]hentriaconta-14,31-diene
  参考文献：
  名称：

  Efficient macrocyclization using methylene-tethered terminal dienes and bis(manganese(III)-enolate)s

  摘要：

  Macrocyclic compounds, which have two fused dihydrofuran rings, were synthesized with complete control by the oxidation of alpha,alpha,omega,omega-tetraaryl-alpha(omega-1)-alkadienes 1(x) with manganese(III)-oligomethylenebis(enolate) complexes directly formed by the reaction of the ohgomethylene bis(3-oxobutanoate)s 2(y) with manganese(III) acetate in situ The oxamethylene-tethered macrodiolides 5 and 7 were also produced in good to moderate yields by a similar oxidation The key intermediate, an election donor-acceptor-like complex, was proposed for the efficient macrocyclization reaction (C) 2010 Elsevier Ltd. All rights reserved

  DOI：

  10.1016/j.tet.2010.02.022
• 作为产物：
  描述：

  3-bromo-1,1-diphenyl-1-propene 、 二乙二醇 生成 1,1,13,13-tetraphenyl-4,7,10-trioxa-1,12-tridecadiene
  参考文献：
  名称：

  Efficient macrocyclization using methylene-tethered terminal dienes and bis(manganese(III)-enolate)s

  摘要：

  Macrocyclic compounds, which have two fused dihydrofuran rings, were synthesized with complete control by the oxidation of alpha,alpha,omega,omega-tetraaryl-alpha(omega-1)-alkadienes 1(x) with manganese(III)-oligomethylenebis(enolate) complexes directly formed by the reaction of the ohgomethylene bis(3-oxobutanoate)s 2(y) with manganese(III) acetate in situ The oxamethylene-tethered macrodiolides 5 and 7 were also produced in good to moderate yields by a similar oxidation The key intermediate, an election donor-acceptor-like complex, was proposed for the efficient macrocyclization reaction (C) 2010 Elsevier Ltd. All rights reserved

  DOI：

  10.1016/j.tet.2010.02.022

文献信息

• Efficient macrocyclization using methylene-tethered terminal dienes and bis(manganese(III)-enolate)s
  作者：Yosuke Ito、Tomomi Yoshinaga、Hiroshi Nishino

  DOI：10.1016/j.tet.2010.02.022

  日期：2010.4

  Macrocyclic compounds, which have two fused dihydrofuran rings, were synthesized with complete control by the oxidation of alpha,alpha,omega,omega-tetraaryl-alpha(omega-1)-alkadienes 1(x) with manganese(III)-oligomethylenebis(enolate) complexes directly formed by the reaction of the ohgomethylene bis(3-oxobutanoate)s 2(y) with manganese(III) acetate in situ The oxamethylene-tethered macrodiolides 5 and 7 were also produced in good to moderate yields by a similar oxidation The key intermediate, an election donor-acceptor-like complex, was proposed for the efficient macrocyclization reaction (C) 2010 Elsevier Ltd. All rights reserved