4-(phenylthio)benzene-1,3-diol | 5633-58-9

• 分子结构分类: 有机化合物 - 有机硫化合物 - 硫醚类
• 英文名称: 4-(phenylthio)benzene-1,3-diol
• 英文别名: 4-Phenylsulfanylbenzene-1,3-diol
• CAS: 5633-58-9
• 化学式: C₁₂H₁₀O₂S
• 分子量: 218.276
• InChiKey: BOKVDWIVXHAHQI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.3
• 重原子数：
  15
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  65.8
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  苯硫酚 、 间苯二酚 在 碘 、 二甲基亚砜 作用下， 以 neat (no solvent) 为溶剂， 反应 3.0h， 以89%的产率得到4-(phenylthio)benzene-1,3-diol
  参考文献：
  名称：

  Iodine catalyzed cross-dehydrogenative C–S coupling by C(sp²)–H bond activation: direct access to aryl sulfides from aryl thiols

  摘要：

  一种高效、简单且便利的绿色协议，利用分子碘在无溶剂、无金属和有氧条件下直接将易得的芳基硫醇与富电子物种进行砜化反应，可高产得各种芳基硫醚。

  DOI：

  10.1039/c5gc00403a

文献信息

• TBAI–HBr system mediated generation of various thioethers with benzenesulfonyl chlorides in PEG₄₀₀
  作者：Dingyi Wang、Shengmei Guo、Rongxing Zhang、Sen Lin、Zhaohua Yan

  DOI：10.1039/c6ra02302a

  日期：——

  An efficient procedure for the formation of C–S bonds via C–H functionalization was developed for the synthesis of aryl sulfides in good to excellent yields using TBAI–HBr system promoted direct sulfenylation of various compounds, such as phenols, pyrazolones, indoles and related heteroarenes. Low cost and widely available arylsulfonyl chlorides were used as the sulfur source to provide various sulfur-containing

  开发了一种通过C–H功能化形成C–S键的有效方法，以使用TBAI–HBr系统促进各种化合物（例如苯酚，吡唑啉酮，吲哚及相关化合物）的直接亚硫基化来合成芳基硫化物，具有良好至优异的收率。杂芳烃。低成本和广泛使用的芳基磺酰氯被用作硫源以提供各种含硫化合物。本协议的特点是方便，绿色，高效，适用范围广，反应时间短。
• Iodine-mediated thiolation of phenol/phenylamine derivatives and sodium arylsulfinates in neat water
  作者：Dingyi Wang、Rongxing Zhang、Sen Lin、Zhaohua Yan、Shengmei Guo

  DOI：10.1039/c5ra24351c

  日期：——

  An efficient and convenient protocol for iodine-mediated thiolation of phenols/phenylamines with sodium benzene-sulfinates in water has been achieved.

  在水中，通过碘介导的苯磺酸钠对酚/苯胺进行硫化的高效便捷协议已经实现。
• Synthesis of Asymmetric Diaryl Sulfides via HI-Mediated C(sp²)-H Sulfenylation of Arenes with Sodium Sulfinates
  作者：Shengnan Sun、Hexia Ye、Tengfei Mao、Yongbiao Guo、Haibo Liu、Junchen Li、Xiaojing Bi

  DOI：10.1021/acs.joc.2c02374

  日期：——

  A novel hydroiodic acid-promoted metal-free C(sp2)-H sulfenylation of electron-rich arenes was developed using stable and easy-to-handle sodium sulfinates as sulfur sources. Diverse kinds of asymmetric aryl sulfides were afforded in good yields from various commercially available aromatic substrates under mild conditions. Comprehensive mechanistic experiments demonstrate that RSO2SR and RSSR are the

  使用稳定且易于处理的亚磺酸钠作为硫源，开发了一种新型氢碘酸促进的富电子芳烃的无金属 C(sp 2 )-H 亚磺酰化反应。在温和条件下，从各种市售芳烃底物中以良好的产率提供了多种不对称芳基硫化物。综合机理实验表明，RSO 2 SR 和 RSSR 是负责氧化还原过程的关键中间体。
• Structure of phosphorous-containing functionalized poly(arylene ether) and compositions prepared therefrom
  申请人：Jiangsu Yoke Technology Co., Ltd

  公开号：US10563019B2

  公开（公告）日：2020-02-18

  A structure of phosphorous-containing functionalized poly(arylene ether), a preparation method thereof, and a composition prepared therefrom are provided. The curable (cross-linkable) composition includes an unsaturated monomer and a phosphorous-containing functionalized poly(arylene ether) having a polymerizable group and a molecular weight between 500 and 20,000. The composition provides excellent fluidity and fast curing rate. After curing, the composition exhibits excellent low dielectric coefficient and dielectric loss, high heat resistance and flame retardancy. It is suitable for prepregs, laminated sheets for printed circuits or the like.

  本发明提供了一种含磷官能化聚芳基醚的结构、制备方法以及由此制备的组合物。固化（可交联）组合物包括不饱和单体和含磷官能化聚（芳基醚），后者具有可聚合基团，分子量在 500 到 20,000 之间。该组合物具有优异的流动性和快速固化率。固化后，该组合物具有优异的低介电系数和介电损耗、高耐热性和阻燃性。它适用于预浸料、印刷电路层压板等。
• Structure of phosphorous-containing functionalized poly(arylene ether), composition containing the same, and copper clad laminate
  申请人：Jiangsu Yoke Technology Co., Ltd

  公开号：US10844180B2

  公开（公告）日：2020-11-24

  A structure of phosphorous-containing functionalized poly(arylene ether), a preparation method thereof, and a composition prepared therefrom are provided. The curable (cross-linkable) composition includes an unsaturated monomer and a phosphorous-containing functionalized poly(arylene ether) having a polymerizable group and a molecular weight between 500 and 20,000. The composition provides excellent fluidity and fast curing rate. After curing, the composition exhibits excellent low dielectric coefficient and dielectric loss, high heat resistance and flame retardancy. It is suitable for prepregs, laminated sheets for printed circuits or the like.

  本发明提供了一种含磷官能化聚芳基醚的结构、制备方法以及由此制备的组合物。固化（可交联）组合物包括不饱和单体和含磷官能化聚（芳基醚），后者具有可聚合基团，分子量在 500 到 20,000 之间。该组合物具有优异的流动性和快速固化率。固化后，该组合物具有优异的低介电系数和介电损耗、高耐热性和阻燃性。它适用于预浸料、印刷电路层压板等。