5-氨基-6-氧代-2-苯基-1(6h)-嘧啶乙酸盐酸盐 | 439910-97-1

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 中文名称: 5-氨基-6-氧代-2-苯基-1(6h)-嘧啶乙酸盐酸盐
• 英文名称: 5-amino-6-oxo-2-phenyl-1,6-dihydropyrimidin-1-ylacetic acid hydrochloride
• 英文别名: 2-(5-Amino-6-oxo-2-phenylpyrimidin-1-yl)acetic acid;hydrochloride
• CAS: 439910-97-1
• 化学式: C₁₂H₁₁N₃O₃*ClH
• 分子量: 281.699
• InChiKey: XGGPKDXOAHOBGW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.0
• 重原子数：
  19
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.08
• 拓扑面积：
  96
• 氢给体数：
  3
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  hydrochloric acid-ethyl acetate 、 4-chloro-5-benzyloxycarbonylamino-6-oxo-2-phenyl-1,6-dihydropyrimidin-1-ylacetic acid 生成 5-氨基-6-氧代-2-苯基-1(6h)-嘧啶乙酸盐酸盐
  参考文献：
  名称：

  摘要：

  DOI：

文献信息

• Pyrimidine derivatives and process for preparing the same
  申请人：——

  公开号：US20040063936A1

  公开（公告）日：2004-04-01

  A pyrimidine derivative compound of formula (I) or a salt thereof and a method for the preparation thereof. The pyrimidine derivative of formula (I) or a salt thereof is useful as important synthetic intermediate for a pharmaceutical a drug. The method for the preparation of the present invention can provide the compound of formula (E), which is useful as a pharmaceutical drug, more efficiently than conventional method does. (All symbols in the formulae have the same meaning as depicted in the specification) 1

  公式（I）的嘧啶衍生物化合物或其盐以及其制备方法。公式（I）的嘧啶衍生物或其盐在药物制剂中作为重要的合成中间体。本发明的制备方法比传统方法更高效地提供公式（E）的化合物，该化合物在药物制剂中具有重要作用。（公式中的所有符号与说明书中描述的含义相同）1
• PYRIMIDINE DERIVATIVES AND PROCESS FOR PREPARING THE SAME
  申请人：ONO PHARMACEUTICAL CO., LTD.

  公开号：EP1346985A1

  公开（公告）日：2003-09-24

  A pyrimidine derivative compound of formula (I) or a salt thereof and a method for the preparation thereof. The pyrimidine derivative of formula (I) or a salt thereof is useful as important synthetic intermediate for a pharmaceutical a drug. The method for the preparation of the present invention can provide the compound of formula (E), which is useful as a pharmaceutical drug, more efficiently than conventional method does. (All symbols in the formulae have the same meaning as depicted in the specification)

  一种式（I）的嘧啶衍生物化合物或其盐及其制备方法。 式（I）的嘧啶衍生物或其盐可用作药物的重要合成中间体。与传统方法相比，本发明的制备方法能更有效地提供可用作药物的式 (E) 化合物。 (式中所有符号的含义与说明书中描述的相同）