4-(1-oxa-4,10-dithia-7-azacyclododec-7-yl)benzldehyde | 240797-80-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-(1-oxa-4,10-dithia-7-azacyclododec-7-yl)benzldehyde
• 英文别名: 4-(1-oxa-4,10-dithia-7-azacyclododec-7-yl)benzaldehyde；4-(1-Oxa-4,10-dithia-7-azacyclododec-7-yl)benzaldehyde
• CAS: 240797-80-2
• 化学式: C₁₅H₂₁NO₂S₂
• 分子量: 311.469
• InChiKey: UJIZSVJMWDZNLA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  20
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.53
• 拓扑面积：
  80.1
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  4-(1-oxa-4,10-dithia-7-azacyclododec-7-yl)benzldehyde 在 哌啶 、 溶剂黄146 作用下， 以 乙醇 为溶剂， 反应 10.0h， 生成 1-phenyl-3-(N-phenyl-1,8-naphthalimid-4-yl)5-[4-(1-oxa-4,10-dithia-7-azacyclododec-7-yl)phenyl]-Δ²-pyrazoline
  参考文献：
  名称：

  On the Development of Sensor Molecules that Display Fe^III-amplified Fluorescence

  摘要：

  Incorporation of a tailor-made size-restricted dithia-aza-oxa macrocycle, 1-oxa-4,10-dithia-7aza-cyclocloclecane, via a phenyl linker into two fluorescent sensor molecules with electronically decoupled, rigidly fixed, and sterically preoriented architectures, a 1,3,5-triaryl-Delta(2)-pyrazoline and a meso-substituted boron-dipyrromethene (BDP), yields amplified fluorescence in the red-visible spectral range upon binding of Fe-III ions. The response to Fe-III and potentially interfering metal ions is studied in highly polar aprotic and protic solvents for both probes as well as in neat and buffered aqueous solution for one of the sensor molecules, the BDP derivative. In organic solvents, the fluorescence of both indicators is quenched by an intramolecular charge or electron transfer in the excited state and coordination of Fe-III leads to a revival of their fluorescence without pronounced spectral shifts. Most remarkably, the unbound BDP derivative shows dual emission in water and can be employed for the selective ratiometric signaling of Fe-III in buffered aqueous solutions.

  DOI：

  10.1021/ja050652t
• 作为产物：
  描述：

  N,N-双(2-溴乙基)苯胺 在 sodium isopropylate 、 三氯氧磷 作用下， 以 异丙醇 为溶剂， 生成 4-(1-oxa-4,10-dithia-7-azacyclododec-7-yl)benzldehyde
  参考文献：
  名称：

  On the Development of Sensor Molecules that Display Fe^III-amplified Fluorescence

  摘要：

  Incorporation of a tailor-made size-restricted dithia-aza-oxa macrocycle, 1-oxa-4,10-dithia-7aza-cyclocloclecane, via a phenyl linker into two fluorescent sensor molecules with electronically decoupled, rigidly fixed, and sterically preoriented architectures, a 1,3,5-triaryl-Delta(2)-pyrazoline and a meso-substituted boron-dipyrromethene (BDP), yields amplified fluorescence in the red-visible spectral range upon binding of Fe-III ions. The response to Fe-III and potentially interfering metal ions is studied in highly polar aprotic and protic solvents for both probes as well as in neat and buffered aqueous solution for one of the sensor molecules, the BDP derivative. In organic solvents, the fluorescence of both indicators is quenched by an intramolecular charge or electron transfer in the excited state and coordination of Fe-III leads to a revival of their fluorescence without pronounced spectral shifts. Most remarkably, the unbound BDP derivative shows dual emission in water and can be employed for the selective ratiometric signaling of Fe-III in buffered aqueous solutions.

  DOI：

  10.1021/ja050652t

文献信息

• A new BODIPY-derived ratiometric senor with internal charge transfer (ICT) effect: colorimetric/fluorometric sensing of Ag⁺
  作者：Changli Zhang、Zhong Han、Mengjia Wang、Zhenghao Yang、Xueqin Ran、Weijiang He

  DOI：10.1039/c7dt04345g

  日期：——

  BODIPY was modified with α-4-aminostyryl group to form a colorimetric/fluorometric dual mode ratiometric Ag⁺ sensor, and the sensor-doped PVC film enables the naked-eye Ag⁺ detection in totally aqueous solution.

  BODIPY被修饰为α-4-氨基苯乙烯基团，形成一种颜色计量/荧光计量双模式比率式Ag+传感器，传感器掺杂的PVC薄膜使得在完全水溶液中可以进行肉眼观察的Ag+检测。
• On the Development of Sensor Molecules that Display Fe^III-amplified Fluorescence
  作者：Julia L. Bricks、Anton Kovalchuk、Christian Trieflinger、Marianne Nofz、Michael Büschel、Alexei I. Tolmachev、Jörg Daub、Knut Rurack

  DOI：10.1021/ja050652t

  日期：2005.10.1

  Incorporation of a tailor-made size-restricted dithia-aza-oxa macrocycle, 1-oxa-4,10-dithia-7aza-cyclocloclecane, via a phenyl linker into two fluorescent sensor molecules with electronically decoupled, rigidly fixed, and sterically preoriented architectures, a 1,3,5-triaryl-Delta(2)-pyrazoline and a meso-substituted boron-dipyrromethene (BDP), yields amplified fluorescence in the red-visible spectral range upon binding of Fe-III ions. The response to Fe-III and potentially interfering metal ions is studied in highly polar aprotic and protic solvents for both probes as well as in neat and buffered aqueous solution for one of the sensor molecules, the BDP derivative. In organic solvents, the fluorescence of both indicators is quenched by an intramolecular charge or electron transfer in the excited state and coordination of Fe-III leads to a revival of their fluorescence without pronounced spectral shifts. Most remarkably, the unbound BDP derivative shows dual emission in water and can be employed for the selective ratiometric signaling of Fe-III in buffered aqueous solutions.