3,3',4'-Trimethyl-4-methoxybenzophenon | 41321-74-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 3,3',4'-Trimethyl-4-methoxybenzophenon
• 英文别名: (3,4-Dimethylphenyl)-(4-methoxy-3-methylphenyl)methanone
• CAS: 41321-74-8
• 化学式: C₁₇H₁₈O₂
• mdl: MFCD09891311
• 分子量: 254.329
• InChiKey: PXCFVJKIUZFOBB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.3
• 重原子数：
  19
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.235
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  5-溴嘧啶 、 3,3',4'-Trimethyl-4-methoxybenzophenon 在 正丁基锂 作用下， 以 四氢呋喃 、 正己烷 为溶剂， 以36%的产率得到(3,4-Dimethyl-phenyl)-(4-methoxy-3-methyl-phenyl)-pyrimidin-5-yl-methanol
  参考文献：
  名称：

  Aromatase inhibition by 5-substituted pyrimidines and dihydropyrimidines

  摘要：

  The inhibition of estrogen biosynthesis has been suggested to be an effective treatment of hormone-dependent diseases, particularly breast cancer. Several series of 5-substituted pyrimidine derivatives have been synthesized and tested for their ability to inhibit the enzyme aromatase (estrogen synthetase). Compounds were evaluated in an in vitro assay that measured the inhibition of rat ovarian microsomal aromatase activity. Greatest inhibitory activity was achieved in the cases of diarylpyrimidinemethanols and diarylpyrimidinyl methanes which were substituted in the 4- and 4'-positions with electron-withdrawing substituents, particularly Cl.

  DOI：

  10.1021/jm00391a016

文献信息

• METHOD FOR PRODUCING POLYMER ELECTROLYTE MOLDED ARTICLE, POLYMER ELECTROLYTE MATERIAL, POLYMER ELECTROLYTE MEMBRANE, AND POLYMER ELECTROLYTE FUEL CELL
  申请人：Izuhara Daisuke

  公开号：US20090208806A1

  公开（公告）日：2009-08-20

  The present invention relates to a method for producing a polymer electrolyte molded article, which comprises forming a polymer electrolyte precursor having a protective group and an ionic group, and deprotecting at least a portion of protective groups contained in the resulting molded article to obtain a polymer electrolyte molded article. According to the present invention, it is possible to obtain a polymer electrolyte material and a polymer electrolyte molded article, which are excellent in proton conductivity and are also excellent in fuel barrier properties, mechanical strength, physical durability, resistance to hot water, resistance to hot methanol, processability and chemical stability. A polymer electrolyte fuel cell using a polymer electrolyte membrane, polymer electrolyte parts or a membrane electrode assembly can achieve high output, high energy density and long-term durability.

  本发明涉及一种制备聚合物电解质成型品的方法，包括形成具有保护基和离子基的聚合物电解质前体，并去除至少一部分所得成型品中的保护基以获得聚合物电解质成型品。根据本发明，可以获得具有优异的质子导电性、燃料屏障性、机械强度、物理耐久性、耐热水性、耐热甲醇性、可加工性和化学稳定性的聚合物电解质材料和聚合物电解质成型品。使用聚合物电解质膜、聚合物电解质部件或膜电极组件的聚合物电解质燃料电池可以实现高输出、高能量密度和长期耐久性。
• TAYLOR, H. M.;JONES, C. D.;DAVENPORT, J. D.;HIRSCH, K. S.;KRESS, T. J.;WE+, J. MED. CHEM., 30,(1987) N 8, 1359-1365
  作者：TAYLOR, H. M.、JONES, C. D.、DAVENPORT, J. D.、HIRSCH, K. S.、KRESS, T. J.、WE+

  DOI：——

  日期：——
• Block copolymer and use thereof
  申请人：Masui Kentaro

  公开号：US20070281195A1

  公开（公告）日：2007-12-06

  A polymer electrolyte satisfying both of proton conductivity and chemical stability such as water resistance at a high level that is preferable as the polymer electrolyte for fuel cells and the like is provided. The invention includes a block copolymer comprising one or more segments having an ion exchange group and one or more segments having substantially no ion exchange group, wherein at least one of the segments having an ion exchange groupis the segment represented by the following general formula (1A), (1B) or (1C): and the segment has ion exchange group density of 4.0 meq/g or more, and the segments having substantially no ion exchange groupis the segment represented by the following general formula (2):
• Aromatic block copolymer, decomposition method thereof and analysis method using the decomposition method
  申请人：Takigawa Hiroshi

  公开号：US20090197763A1

  公开（公告）日：2009-08-06

  Provided is a decomposition method of an aromatic block copolymer, wherein the aromatic block copolymer comprises a segment 1 represented by the following general formula (1) and a segment 2 comprising a structural unit represented by the following general formula (2) and/or a structural unit represented by the following general formula (3), and the segment 2 is subjected to chemical decomposition. (wherein m represents an integer of 5 or more, Ar 1 represents a divalent aromatic group that may have a substituent, and Ar 1 s of 5 or more may be the same as or different from each other,) Ar 10 —X 10   (2) Ar 20 —Y 20 —Ar 21 —X 20   (3) (wherein Ar 10 , Ar 20 and Ar 21 each independently represent a divalent aromatic group that may have a substituent, X 10 and X 20 each independently represent an oxygen atom, a sulfur atom, an alkylene group having 1 to 10 carbon atoms or a fluorine-substituted alkylene group having 1 to 10 carbon atoms, and Y 20 represents a sulfonyl group, a carbonyl group or a fluorine-substituted alkylene group having 1 to 20 carbon atoms).
• Condensed ring-containing polymer electrolyte and application thereof
  申请人：Yamada Takashi

  公开号：US20100239947A1

  公开（公告）日：2010-09-23

  The polymer electrolyte of the present invention comprises a structural unit represented by the following general formula (1) in weight fraction of 1 to 30% by weight: (in the formula, A-ring and B-ring each independently represent an optionally-substituted aromatic hydrocarbon ring or an optionally-substituted heterocyclic ring; X 1 and X 2 each independently represent —CO—, —SO— or —SO 2 —; n and m each independently represent 0, 1 or 2, and n+m is not less than 1; when n is 2, two X 1 s may be the same as or different from each other; when m is 2, two X 2 s may be the same as or different from each other; and X represents a direct bond or a divalent group). The polymer electrolyte has excellent water resistance while having high ion-conductivity.