N-palmitoylaspartic acid | 130056-61-0

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: N-palmitoylaspartic acid
• 英文别名: N-hexadecanoylaspartic acid；2-(hexadecanoylamino)butanedioic acid
• CAS: 130056-61-0
• 化学式: C₂₀H₃₇NO₅
• 分子量: 371.517
• InChiKey: ZYJZBFYRVKLOAA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6
• 重原子数：
  26
• 可旋转键数：
  18
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.85
• 拓扑面积：
  104
• 氢给体数：
  3
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  aspartic acid TMS 、 棕榈酰氯 在 水 作用下， 生成 N-palmitoylaspartic acid
  参考文献：
  名称：

  N-acyl derivatives of D,L-aspartic acid: Synthesis, psychotropic properties, and effect on binding of3H-glutamate to brain membranes

  摘要：

  DOI：

  10.1007/bf00766246

文献信息

• PREPARATION OF AMINO ACID-FATTY ACID AMIDES
  申请人：Chaudhuri Shan

  公开号：US20080200704A1

  公开（公告）日：2008-08-21

  The present invention describes compounds produced from an amino acid molecule and a fatty acid molecule. The compounds being in the form of amino-fatty acid compounds being bound by an amide linkage, or mixtures thereof made by reacting amino acids or derivatives thereof with an appropriate fatty acid previously reacted with a thionyl halide. The administration of such molecules provides supplemental amino acids with enhanced bioavailability and the additional benefits conferred by the specific fatty acid.

  本发明描述了由氨基酸分子和脂肪酸分子产生的化合物。这些化合物采用酰胺键结合的氨基脂肪酸化合物的形式存在，或者是由氨基酸或其衍生物与先前与硫酰卤反应的适当脂肪酸反应而成的混合物。这些分子的使用可提供具有增强生物利用度和特定脂肪酸所赋予的额外益处的补充氨基酸。
• Process for producing polymer particles
  申请人：KAO CORPORATION

  公开号：EP0733648A1

  公开（公告）日：1996-09-25

  A process for producing polymer particles comprising polymerizing a water-soluble polymerizable monomer in a system comprising a hydrophobic organic solvent inert to the polymerization and an aqueous solution of the water-soluble polymerizable monomer, the process being characterized in that the polymerization is carried out in the presence of, as a dispersant, an anionic surface active agent represented by formula (I): wherein R1 represents a straight-chain or branched alkyl, alkenyl or 2-hydroxyalkyl group having 5 to 29 carbon atoms; M1 and M2, which may be the same or different, each represent an alkali metal ion, an ammonium ion or a hydrogen atom; and n represents 1 or 2.

  一种生产聚合物颗粒的工艺，包括在由惰性于聚合的疏水性有机溶剂和水溶性可聚合单体的水溶液组成的体系中聚合水溶性可聚合单体，该工艺的特征在于聚合是在由式(I)代表的阴离子表面活性剂作为分散剂存在的情况下进行的： 其中 R1 代表具有 5 至 29 个碳原子的直链或支链烷基、烯基或 2-羟基烷基；M1 和 M2 可以相同或不同，各自代表碱金属离子、铵离子或氢原子；n 代表 1 或 2。
• Skin model
  申请人：Symrise GmbH & Co. KG

  公开号：EP1927656A1

  公开（公告）日：2008-06-04

  The present invention relates to the use of a pig skin sample as a skin model, particularly for the assessment of pharmacological and cosmetic effects.

  本发明涉及使用猪皮肤样本作为皮肤模型，特别是用于评估药理和美容效果。
• Ex vivo human skin model
  申请人：Symrise GmbH & Co. KG

  公开号：EP2019316A2

  公开（公告）日：2009-01-28

  The present invention relates to the use of an ex vivo human skin sample as a biological model, particularly for the assessment of pharmacological and cosmetic effects.

  本发明涉及使用体外人体皮肤样本作为生物模型，特别是用于评估药理和美容效果。
• HYDROPHOBIC ALGINIC ACID PARTICLE GROUP AND METHOD FOR PRODUCING SAME
  申请人：Nisshinbo Holdings Inc.

  公开号：EP3922666A1

  公开（公告）日：2021-12-15

  The present invention provides a hydrophobic alginic acid particle group which is obtained by subjecting a polyvalent metal alginate to a hydrophobization treatment, and which is configured such that the water absorption per 100 g of the particles is lower than the oil absorption per 100 g of the particles.

  本发明提供了一种疏水性海藻酸粒子群，它是通过对多价金属海藻酸盐进行疏水处理而获得的，其配置使得每 100 克粒子的吸水率低于每 100 克粒子的吸油量。