2-[(2S)-piperidin-2-yl]acetamide

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 2-[(2S)-piperidin-2-yl]acetamide
• 化学式: C₇H₁₄N₂O
• 分子量: 142.2
• InChiKey: RNGRYWXHDOJTFX-LURJTMIESA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.4
• 重原子数：
  10
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  55.1
• 氢给体数：
  2
• 氢受体数：
  2

文献信息

• [EN] DUAL AMYLIN AND CALCITONIN RECEPTOR AGONISTS AND USES THEREOF<br/>[FR] DOUBLES AGONISTES DU RÉCEPTEUR DE LA CALCITONINE ET DE L'AMYLINE ET LEURS UTILISATIONS
  申请人：[en]ELI LILLY AND COMPANY

  公开号：WO2022133187A1

  公开（公告）日：2022-06-23

  The present disclosure related to the field of medicine. More particularly, the disclosure is in the field of treatment of diabetes, obesity, and/or dyslipidemia. The disclosure relates to compounds that agonize both the calcitonin and amylin receptors and can lower food intake, body weight, glucose and/or triglycerides, so can be used to treat diabetes, obesity and/or dyslipidemia. The present disclosure also includes pharmaceutical compositions containing such compounds and therapeutic uses of such compounds and compositions.