Gorlic acid | 502-31-8

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: Gorlic acid
• 英文别名: (E)-13-cyclopent-2-en-1-yltridec-6-enoic acid
• CAS: 502-31-8
• 化学式: C₁₈H₃₀O₂
• 分子量: 278.4
• InChiKey: XADKGDBMULSEAC-DUXPYHPUSA-N

物化性质

• 熔点：
  6 °C
• 沸点：
  232.5 °C
• 密度：
  0.9364 g/cm3(Temp: 18 °C)
• 保留指数：
  2205.1

计算性质

• 辛醇/水分配系数(LogP)：
  6.1
• 重原子数：
  20
• 可旋转键数：
  12
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.72
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

安全信息

• 海关编码：
  2916209090

文献信息

• FATTY ACID CONJUGATES OF QUETIAPINE, PROCESS FOR MAKING AND USING THE SAME
  申请人：KemPharm, Inc.

  公开号：US20170247368A1

  公开（公告）日：2017-08-31

  The presently described technology provides a novel class of prodrugs of quetiapine that can be synthesized by chemically conjugating fatty acids to quetiapine. Pharmaceutical compositions and methods of synthesizing conjugates of the present technology are also provided. Methods of treating patients with the compositions of the present technology are also provided.

  目前所描述的技术提供了一种新型的奎硫平前药类，可以通过将脂肪酸与奎硫平进行化学共轭来合成。同时，还提供了制备本技术共轭物的药物组合物和方法。还提供了使用本技术组合物治疗患者的方法。
• BIODEGRADABLE COMPOSITIONS AND MATERIALS
  申请人：Putnam David Aaron

  公开号：US20100104625A1

  公开（公告）日：2010-04-29

  The present invention provides compounds of Formula I, materials comprising one or more compounds of Formula I and one or more biologically active agents, pharmaceutical compositions comprising an inventive material and a pharmaceutically acceptable excipient, methods of making compounds of Formula I, methods of making inventive materials, and methods of using pharmaceutical compositions comprising an inventive material and a pharmaceutically acceptable excipient.
• Fatty Acid Conjugates of Quetiapine, Process for Making and Using the Same
  申请人：Mickle Travis

  公开号：US20110223207A1

  公开（公告）日：2011-09-15

  The presently described technology provides a novel class of prodrugs of quetiapine that can be synthesized by chemically conjugating fatty acids to quetiapine. Pharmaceutical compositions and methods of synthesizing conjugates of the present technology are also provided. Methods of treating patients with the compositions of the present technology are also provided.
• US8900604B2
  申请人：——

  公开号：US8900604B2

  公开（公告）日：2014-12-02
• US9511149B2
  申请人：——

  公开号：US9511149B2

  公开（公告）日：2016-12-06