N-methyl-3-oxoheptaneamide | 1335323-30-2

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: N-methyl-3-oxoheptaneamide
• 英文别名: N-methyl-3-oxoheptanamide
• CAS: 1335323-30-2
• 化学式: C₈H₁₅NO₂
• 分子量: 157.213
• InChiKey: YXOVUJYUNZUQFZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.8
• 重原子数：
  11
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  46.2
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  3-酮庚酸甲酯 、 甲胺 在 raw product 作用下， 以 乙醇 、 水 为溶剂， 反应 72.0h， 以5.9 g of the title compound was obtained的产率得到N-methyl-3-oxoheptaneamide
  参考文献：
  名称：

  Fe(III) complex compounds for the treatment and prophylaxis of iron deficiency symptoms and iron deficiency anemias

  摘要：

  本发明涉及铁（III）配合物化合物和包含它们的药物组合物，用于作为药物，特别是用于治疗和/或预防缺铁症状和缺铁性贫血。

  公开号：

  US09394324B2

文献信息

• Fe(III) Complex Compounds For The Treatment And Prophylaxis Of Iron Deficiency Symptoms And Iron Deficiency Anemias
  申请人：Bark Thomas

  公开号：US20130109662A1

  公开（公告）日：2013-05-02

  The invention relates to iron(III) complex compounds and pharmaceutical compositions comprising them for the use as medicaments, in particular for the treatment and/or prophylaxis of iron deficiency symptoms and iron deficiency anemias.

  这项发明涉及铁（III）配合物和包括它们的药物组合物，用作药物，特别是用于治疗和/或预防缺铁症状和缺铁性贫血。
• Method of preparing a polyamide acid composition for preparing polyimide
  申请人：KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA

  公开号：EP0114059A2

  公开（公告）日：1984-07-25

  A polyamide acid composition for preparing a polyimide which is improved in the stability in a form of solution and can extend the pot life of the composition comprising a solution of a polyamide acid in an organic solvent, the polyamide acid being a precursor of the polyimide, and an N-substituted heterocyclic compound as a chemical treating agent which can lower a rate of conversion of the polyamide acid to the polyimide. The pot life can be extremely extended to give the composition an enough flowability for a long time without reducing the excellent properties such as a heat resistance of the obtained polyimide.

  一种用于制备聚酰亚胺的聚酰胺酸组合物，该组合物在溶液形式下的稳定性得到改善，并可延长其罐装寿命，该组合物包括聚酰胺酸在有机溶剂中的溶液，聚酰胺酸是聚酰亚胺的前体，以及一种 N-取代杂环化合物作为化学处理剂，可降低聚酰胺酸转化为聚酰亚胺的速率。可以极大地延长罐装寿命，使组合物在长时间内具有足够的流动性，而不会降低所获得的聚酰亚胺的优异性能，如耐热性。
• SYNTHETIC INTERMEDIATES FOR PRODUCING MACROCYCLES AS FACTOR XIA INHIBITORS
  申请人：Bristol-Myers Squibb Company

  公开号：EP3786165A1

  公开（公告）日：2021-03-03

  The present invention provides synthetic intermediates useful in the preparation of compounds of Formula (I) or a stereoisomer, a tautomer, or a pharmaceutically acceptable salt thereof, wherein all the variables are as defined herein. These compounds are selective Factor Xia inhibitors or dual inhibitors of fXIa and plasma kallikrein.

  本发明提供了用于制备式（I）化合物或其立体异构体、同分异构体或药学上可接受的盐的合成中间体，其中所有变量如本文所定义。这些化合物是选择性夏因子抑制剂或 fXIa 和血浆钙激酶的双重抑制剂。
• Polyamide acid composition for preparing polyimide and process for preparing polyimide from the same
  申请人：KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA

  公开号：EP0083690B1

  公开（公告）日：1986-03-12
• MACROCYCLES AS FACTOR XIA INHIBITORS
  申请人：Bristol-Myers Squibb Company

  公开号：EP2534154B1

  公开（公告）日：2020-08-05