5-(Butylamino)-5-oxopentanoic acid | 106754-06-7

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 5-(Butylamino)-5-oxopentanoic acid
• CAS: 106754-06-7
• 化学式: C₉H₁₇NO₃
• mdl: MFCD06065384
• 分子量: 187.24
• InChiKey: MEWUUTJBMVVWDK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.6
• 重原子数：
  13
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.777
• 拓扑面积：
  66.4
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• BIODEGRADABLE POLYESTER- AND POLY(ESTER AMIDE) BASED X-RAY IMAGING AGENTS
  申请人：Clemson University

  公开号：US20150290344A1

  公开（公告）日：2015-10-15

  Biodegradable, radio-opaque polyesters and poly(ester amides) are described herein. The polyesters contain a plurality of radio-opaque agents or radio-opaque agent-containing moieties that are covalently bound along or from the polymer backbone. The agents/moieties may be bound to the termini of the polymer provided they are bound within the polyester backbone as well. The polyester can be aliphatic or aromatic. The polyester and poly(ester amide) is substituted with a plurality of radio-opaque graft agents or prepared from an appropriate radio-opaque monomer agent. The materials can be used for any application where a radio-opaque material is desired or necessary. The materials can be used to form, in whole or in part, a medical device, or coating thereon or therein.

  本文介绍了可生物降解、放射性不透明的聚酯和聚酯酰胺。聚酯中含有多种放射性不透明剂或含有这些剂的官能团，这些剂/官能团沿着或从聚合物骨架上共价结合。这些剂/官能团可以结合到聚合物的末端，只要它们也在聚酯骨架内结合。聚酯可以是脂肪族或芳香族的。聚酯和聚酯酰胺被多种放射性不透明的嫁接剂取代或由适当的放射性不透明单体剂制备而成。这些材料可用于任何需要放射性不透明材料的应用。这些材料可用于制造医疗器械的整体或部分，或用于其内部或外部的涂层。
• Novel peptides as NS3-serine protease inhibitors of hepatitis C virus
  申请人：Saksena K. Anil

  公开号：US20070032433A1

  公开（公告）日：2007-02-08

  The present invention discloses novel compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such compounds as well as methods of using them to treat disorders associated with the HCV protease.

  本发明揭示了具有HCV蛋白酶抑制活性的新化合物，以及制备这些化合物的方法。在另一种实施方式中，本发明揭示了包含这些化合物的药物组合物，以及使用它们治疗与HCV蛋白酶相关的疾病的方法。
• NOVEL PEPTIDES AS NS3-SERINE PROTEASE INHIBITORS OF HEPATITIS C VIRUS
  申请人：Saksena Anil K.

  公开号：US20110117057A1

  公开（公告）日：2011-05-19

  The present invention discloses novel compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such compounds as well as methods of using them to treat disorders associated with the HCV protease.

  本发明披露了具有HCV蛋白酶抑制活性的新化合物，以及制备这些化合物的方法。在另一种实施方式中，本发明披露了包含这些化合物的制药组合物，以及使用它们治疗与HCV蛋白酶相关的疾病的方法。
• REVERSIBLY THERMOCHROMIC COMPOSITION, AND REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT HAVING SAME ENCLOSED THEREIN
  申请人：The Pilot Ink Co., Ltd

  公开号：EP3608386A1

  公开（公告）日：2020-02-12

  [Problems] The present invention provides a highly marketable reversibly color changeable composition which provides a vivid yellow to orange color during color development, turns colorless during decoloration, and improves light resistance and a reversibly thermochromic microcapsule pigment encapsulating the same. [Solution] Disclosed are a reversibly thermochromic composition including: (a) a specific pyridine derivative as an electron-donating color-developing organic compound; (b) an electron-accepting compound; and (c) a reaction medium which reversibly induces an electron transfer reaction between the component (a) and the component (b) in a specific temperature range, and a reversibly thermochromic microcapsule pigment encapsulating the same.

  问题 本发明提供了一种高度市场化的可逆变色组合物，该组合物在显色过程中提供鲜艳的黄色至橙色，在脱色过程中变成无色，并提高了耐光性，还提供了封装该组合物的可逆热变色微胶囊颜料。 [解决方案］ 本发明公开了一种可逆热致变色组合物，包括：（a）作为电子捐赠显色有机化合物的特定吡啶衍生物；（b）电子接受化合物；和（c）在特定温度范围内可逆地诱导组分（a）和组分（b）之间发生电子转移反应的反应介质，以及封装该组合物的可逆热致变色微胶囊颜料。
• REVERSIBLE THERMOCHROMIC COMPOSITION, REVERSIBLE THERMOCHROMIC MICROCAPSULE PIGMENT COMPRISING SAME, AND WRITING INSTRUMENT USING SAME
  申请人：THE PILOT INK CO., LTD.

  公开号：EP3950068A1

  公开（公告）日：2022-02-09

  [Problems] Provided are a highly marketable reversibly thermochromic composition that provides a black color during color development by using a fluoran derivative having a specific structure as an electron-donating color-developing organic compound, turns colorless during decoloration, and is excellent in contrast between a colored state and a decolored state and a microcapsule pigment encapsulating the same. [Solution] Disclosed are a reversibly thermochromic composition including: (a) a fluoran derivative having a specific structure as an electron-donating color-developing organic compound; (b) an electron-accepting compound; and (c) a reaction medium which reversibly induces an electron transfer reaction between the component (a) and the component (b) in a specific temperature range, and a reversibly thermochromic microcapsule pigment encapsulating the same.

  [问题]提供了一种极具市场前景的可逆热致变色组合物，该组合物通过使用具有特定结构的芴衍生物作为电子捐赠显色有机化合物，在显色过程中提供黑色，在脱色过程中变成无色，并且在有色状态和脱色状态之间具有极佳的对比度，同时还提供了封装该组合物的微胶囊颜料。 [解决方案]本发明公开了一种可逆热变色组合物，包括：（a）具有特定结构的氟烷衍生物，作为电子捐赠显色有机化合物；（b）电子接受化合物；以及（c）反应介质，该介质可在特定温度范围内可逆地诱导组分（a）和组分（b）之间的电子转移反应，以及封装该组合物的可逆热变色微胶囊颜料。